DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment KaiR1D and grik5-like.1

DIOPT Version :9

Sequence 1:	NP_650925.1	Gene:	KaiR1D / 42473	FlyBaseID:	FBgn0038837	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001072565.1	Gene:	grik5-like.1 / 780020	XenbaseID:	XB-GENE-5860197	Length:	479	Species:	Xenopus tropicalis

Alignment Length:	446	Identity:	159/446 - (35%)
Similarity:	261/446 - (58%)	Gaps:	26/446 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 KQQEIEANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVP 469
            |::|.......|.|.||||:..|:.|:.||.:        ||:.:||:.|:::||||||.|:.|.
Frog    30 KEKERSKRQALKHLTVTTIMEQPFSMKTESGM--------EGFCIDLLSELAQSLGFNYTIKEVK 86

  Fly   470 DGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRK-PIKQ 533
            ||.||:.:: .|.||||:.|:|.:.||||:|.||||..||:.:.||.|||..|:|||.|| .:.:
Frog    87 DGRYGAKDQ-DGNWNGMVGEVLRKEADLAVAPLTITGARERELAFTKPFMQTGISILLRKDDVSE 150

  Fly   534 PPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVESQFTLLNCMWFA 598
            ...||.||:|.|.:.||.:..||:..|:.||::.:.:|.||   |:...|  ::.|..||.:||.
Frog   151 NSYLFGFLTPFSKETWIGILVAYVVTSLCLFLVGRLSPCEW---TELSTE--QNNFNFLNSLWFG 210

  Fly   599 IGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSP-IESAEDLAKQTR 662
            :|:...||.:..||::|.|::|.|||.|:::::::|.|:.||||..:.|.:. |::.|||..|..
Frog   211 VGAFTLQGAEPHPKSVSARIIAVIWWIFSIVLVAAYIASFAAFLNSDSMQTTNIQTFEDLVNQRT 275

  Fly   663 IKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSI 727
            :::|.:...||..||::||..||:.::.:|:..:..:...|..|||.||.  :.:||||.||...
Frog   276 LEFGTINSSSTFQFFKNSKNPTYRMIYEYMDKRKDELLVKSFAEGVRRVK--ESNYAFLGESVMQ 338

  Fly   728 EYVTERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGK 792
            :.:..::|:|.:...::..:.||||...:||....::..||:..|.|.:..|:.|||     ...
Frog   339 DIMVAKHCDLVRAPQIIAGRGYGIAASLDSPLIKPLSVAILEQTESGNIEYLRKKWW-----DNT 398

  Fly   793 CRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKVAVEERLS 848
            |.:   |.|:..|.:....:||:|::|..|:.:..:.|:.|.|.|:|..|.:::.|
Frog   399 CNM---KRSAGWNPVQPHTLGGIFLILGIGLALGVIAALVELVLKARNNADQQKKS 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..397	CDD:107377
		ANF_receptor	42..378	CDD:279440
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:304360	140/371 (38%)
		Lig_chan	547..823	CDD:278489	87/276 (32%)
grik5-like.1	NP_001072565.1	PBP2_iGluR_non_NMDA_like	41..396	CDD:270403	141/375 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910