Protein Alignment KaiR1D and grin1a

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_073791110.1
• Gene: grin1a / 767745
• ZFINID: ZDB-GENE-051202-1
• Length: 966
• Species: Danio rerio
• Alignment Length: 947
• Identity: 224/947 - (23%)
• Similarity: 389/947 - (41%)
• Gaps: 195/947 - (20%)

  Fly    11 LLLLQLILNCR--KAQSLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRSKL-VAQIER 72
            ||||..:.:|.  :....|.|:.||.:.  :....|..|:.||.:.|   .:..|.|. :..|..
Zfish     3 LLLLAALFSCSCVRGGCEPKIVNIGAVL--SQKRYEQVFKDAVTQAN---QVYGRDKFKLTAISV 62

  Fly    73 ISPFDSFHAGKRVC-GLLNIGVAAIF---GPQS---------SHTASHVQ----------SICDN 114
            ....::......|| .|::..|.||.   .|||         |:||...:          ||..:
Zfish    63 THKANAIQMALSVCEDLISSQVYAILVSHPPQSNDHLTPTPVSYTAGFYRIPVVGLTTRMSIYSD 127

  Fly   115 MEIPHLENRWDYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGWKTFTII---------------- 163
            ..| ||           |.|..:.|:.:. :..:.|::|.:.|....:|
Zfish   128 KSI-HL-----------SFLRTVPPYSHQ-AHVWFDMMREFRWNHIILIVSDDHEGRAAQKRLET 179

  Fly   164 -------------YENNDGIVRLQELLKAHGMTPFPITVRQLSDSGDYRPLLKQIKNSAEAHIVL 215
                         |||.|      :|...:...|....|.|.:...:...||.:.|......|:|
Zfish   180 LLEERETKNKKRNYENQD------QLSYDNKRGPKAEKVLQFNQETNLTALLLEAKELEARVIIL 238

  Fly   216 DCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLINEKIVSDVVRQ 280
            ..|.|....|.|.|:.:.|....:.:||...::....|.|...|   :.|.:|||.|
Zfish   239 SASEEDAAAVYKTARFLNMTGSGYVWLVGEREMSGKALSEAPDG---LIGLQLINGK-------- 292

  Fly   281 WSIDEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPISCDGQST-WQHG--FS 342
                              :|:|.:.|||.:.|:::.:|...:.|...|..|.|.:. |:.|  |.
Zfish   293 ------------------NESAHISDAVAVVAQSIQELFEKENITEPPRGCVGNTNIWKTGPLFK 339

  Fly   343 LINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAGIRKIGTWNSTLPDGINFTRTFSQKQQ 407
            .: .|.....:|||..::|:..|.|......|:....:.:.::|.:|.        |:....||:
Zfish   340 RV-LMSSKYPEGLTGRVEFNDDGDRKYAHYSILNYQKSRLIQVGIYNG--------TQVVMNKQR 395

  Fly   408 EI----------EANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFE----------------- 445
            :|          .....:..|.:.||...|:...|.:.:..:..:::.
Zfish   396 KIIWPGGETERPRGFQMSTRLKIVTIHQEPFVYVKPTTLEGTCKEEYTPNGVLIKKVICTGPNET 460

  Fly   446 ------------GYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTG----EWNGMIRELLEQR 494
                        |:.:||:.:::.::.|.|::.||.||.:|:..::..    |||||:.|||...
Zfish   461 IPGRPIVPQCCYGFCIDLLIKLALTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLGGL 525

  Fly   495 ADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGV 559
            ||:.:|.|||..||.|.::|:.||...|::||.:|.|.: ..|.||:.|....:|:.:..:...|
Zfish   526 ADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPR-STLDSFMQPFQSTLWLLVGLSVHVV 589

  Fly   560 SVLLFILAKFTPYEWPAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGC-DFLPKALSTRMVAGIW 623
            :|:|::|.:|:|:  ..:.....|:.|...||.:.|||:.|.|:..|. :..|::.|.|::..:|
Zfish   590 AVMLYLLDRFSPF--GRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVW 652

  Fly   624 WFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTRIK-------YGALKGGSTAAFF-RDS 680
            ..|.:|:::||||||||||.::|.:..|....|    .|::       |..:|..|...:| |..
Zfish   653 AGFAMIIVASYTANLAAFLVLDRPEERITGIND----PRLRNPSDKFIYATVKQSSVDIYFRRQV 713

  Fly   681 KISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVGGMLD 745
            ::||   |:..||...    ..|..|.::.|...| .:||:.:|..:|:...:.|:|...|.:..
Zfish   714 ELST---MYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEFEASQKCDLVTTGELFF 770

  Fly   746 TKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLA 810
            ...:||....:||::..::..||...|.|.:..|...|.:.:        |....|:|...|...
Zfish   771 RSGFGIGMRKDSPWKQNVSLAILSSHENGFMEDLDKTWVRYQ--------ECDSRSNAPATLTFE 827

  Fly   811 NVGGVFVVLMGGMGVACVIAVCEFVWKSRKVAVEERL 847
            |:.|||:::.||:.....:...|..:|..|.|..:::
Zfish   828 NMAGVFMLVAGGIAAGIFLIFIEIAYKRHKDARRKQM 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	87/424 (21%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	112/411 (27%)
grin1a	XP_073791110.1	None