DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment KaiR1D and si:ch211-251b21.1

DIOPT Version :9

Sequence 1:	NP_650925.1	Gene:	KaiR1D / 42473	FlyBaseID:	FBgn0038837	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001138274.1	Gene:	si:ch211-251b21.1 / 571720	ZFINID:	ZDB-GENE-060809-5	Length:	458	Species:	Danio rerio

Alignment Length:	432	Identity:	158/432 - (36%)
Similarity:	243/432 - (56%)	Gaps:	28/432 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   418 LVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTGE 482
            |.||||...||.|.|.|        :.||:.:|::..||..|||.|.:.||.||.||..:. :|.
Zfish    25 LKVTTIKEEPYAMSKGS--------ELEGFCIDMLSAISNKLGFKYDVHLVKDGRYGKTDD-SGN 80

  Fly   483 WNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLF-SFLSPLSL 546
            |||||.|::...||:|:|.||:|.:||..||.:.|||..|:|.:.||.:....:.| |.|...|.
Zfish    81 WNGMIGEVVRGEADIAVAPLTLTAQREAVVDMSKPFMQTGLSFIMRKDLGSDDSQFLSLLKLFST 145

  Fly   547 DVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGCDFLP 611
            ::|:.:..|||..|:.:|::::.:|.||     ...||..:.|||.:..|:.:|:|..||....|
Zfish   146 EMWMGVLVAYLLTSICIFLVSRISPCEW-----EQPEKDNNSFTLSHSFWYTVGALTLQGAGPHP 205

  Fly   612 KALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTRIKYGALKGGSTAAF 676
            ||||.|::..|||.|:|::::.|.|||:.:|..:.....|::.||||.|..|:||.:|..|:..|
Zfish   206 KALSGRVITSIWWIFSLVLLACYFANLSLWLHSDNQQLSIKTFEDLANQNVIEYGTIKDSSSFNF 270

  Fly   677 FRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVG 741
            |::|...||.|::..::.|:.  ::.:..||..|..  ||:|||:.||.|::....|.|.||:..
Zfish   271 FKNSNNPTYHRIYEHIKEAQS--YSLNAAEGFRRAQ--KGNYAFIGESVSLDLAVARYCNLTRAP 331

  Fly   742 GMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANE 806
            .::..:.|.||.|..||....::..||:|.|.|:|...::|||     ...|..:.||.:    .
Zfish   332 EIIGMRGYSIAAPLGSPLIKNLSVAILRLSESGELDYFRSKWW-----ASSCVAKDSKGA----P 387

  Fly   807 LGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKVAVEERLS 848
            |..|::.|||::|..|:|:...:|:.|...||||||..|:.|
Zfish   388 LKPASLKGVFLLLAFGLGLGIFLALMELAAKSRKVANSEQKS 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..397	CDD:107377
		ANF_receptor	42..378	CDD:279440
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:304360	136/367 (37%)
		Lig_chan	547..823	CDD:278489	92/275 (33%)
si:ch211-251b21.1	NP_001138274.1	PBP2_iGluR_non_NMDA_like	25..375	CDD:270403	137/372 (37%)
si:ch211-251b21.1	NP_001138274.1	Lig_chan	146..396	CDD:278489	88/267 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.770