Protein Alignment KaiR1D and grin3ba

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_021323058.1
• Gene: grin3ba / 566411
• ZFINID: ZDB-GENE-070912-354
• Length: 1118
• Species: Danio rerio
• Alignment Length: 959
• Identity: 216/959 - (22%)
• Similarity: 369/959 - (38%)
• Gaps: 241/959 - (25%)

  Fly    20 CRKAQSLPDIIKIGGLFHPADDHQELAFRQAVDR--------------INADRSILPRSKLVAQI 70
            |.....:...:::|.|.   ...|:...:.|::|              .|....:|.|..|....
Zfish    34 CHILARIGHTVRLGALL---PTRQQSRIQGALNRALVHLRQSGNNFLPYNLSLEVLSREPLNGDP 95

  Fly    71 ERISPFDSFHAGKRVC-GLLNIGVAAIFG-PQSSHTASHVQSICDNMEIPHL-----------EN 122
            |  |.|      :.|| .::..||:|:.. |||......|:.:...:|||.:           :|
Zfish    96 E--SMF------RCVCQDIVVQGVSAVLAFPQSHEELIQVEFMSSFLEIPFISIIEQGEPLKTQN 152

  Fly   123 RWDYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGWK--TFTII-YENNDGIVRLQELLK------ 178
            |:..:      ::...| |:.||...:.::...||:  ..|:. ...|.|:  |:||.:
Zfish   153 RFHLQ------MMTRMP-PSGLSDLLLAVLLRGGWQGGAATVCPGGGNTGM--LEELQQRGHLGL 208

  Fly   179 --AHGMTPFPITVRQLSD--SGD-----YRPLLKQIKNSAEAHIVL-----DCSTERIHEVLKQA 229
              ||......:.:.:|.:  |.|     ...||.:..::..:.:||     :|:.    .||..|
Zfish   209 DGAHWHLWETLNLSRLEENISEDKVMELLSQLLSRTPSAPASSVVLFGSDPECTA----TVLHCA 269

  Fly   230 QQI-GMMSDYH---SYLVTSLDLHTVN--LDEFRYGGTNITGFRLINEKIVSDVVRQWSIDEKGL 288
            .|: |.:...|   .|.::...||::.  |....||.        :|.|.::..:|    |...|
Zfish   270 HQLSGTLPPMHWIMGYPLSLDSLHSIGSPLGLMAYGE--------VNRKPLNFYIR----DTLQL 322

  Fly   289 LRSA--NLTTVRSETALMYDAVHLFAKA-LHDLD------------------------------- 319
            :..|  ..|.||.:.||:.:.|:.|.|. .|:|.
Zfish   323 IGRAVYAATMVRPDLALIQNMVNCFDKPNKHELPSSGQYLARFLSNTSFTGLTGPVRVERSFSRV 387

  Fly   320 -TSQQIDIHPISCD--GQSTWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAG 381
             |||:..|..:..|  ||.:|....|..:....:|.:||...:. .||  |.|         ..|
Zfish   388 LTSQRFHIWSLQRDPLGQPSWVTVASWQSGRLELEEQGLWPGVT-QHQ--RED---------GPG 440

  Fly   382 IRKIGTWNSTLPDGINFTRTFSQKQQEIEANLKNKTLVVTTILSNPYCMRKE------------- 433
            ||..|.|.:.||                   :....|.|.|::.:|:...:|
Zfish   441 IRLGGRWQAGLP-------------------VAGSRLRVVTLVEHPFVFTREVDEEGQCPAGQLC 486

  Fly   434 -----------------------SAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVPDGSYGS 475
                                   |::|........||.:||:.::::.:.|.:.:.:|.||.||:
Zfish   487 LDPQTNNSEVLNQLFRELEQTNSSSLPTDMRKCCYGYCIDLLEKLAEDMHFEFDLYIVGDGKYGA 551

  Fly   476 LNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSF 540
            ..  .|.|:|::.:||...||:|:...:|...|.:.:|||:||.:..:.||.|......| :.:|
Zfish   552 WK--GGRWSGLVGDLLSGVADMAVTSFSINSARSRVIDFTSPFFSTSLGILVRSKDTAAP-IGAF 613

  Fly   541 LSPLSLDVWIYMATAYLGVSVLLFILAKF-TPYEW--PAYTDAHGE---KVESQFTLLN-CMWFA 598
            :.||...:|:       |:.|.|.|.|.| |.|||  |.....||.   :|.|..:.|| |....
Zfish   614 MWPLHWSMWV-------GIFVALHITALFITLYEWNSPFGMTPHGRNRIRVFSYSSALNLCYAIL 671

  Fly   599 IGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLA---KQ 660
            .|..:   ....||..:.|.:..:|..|.|:::|||||||||.:..|:....:....|:.   ..
Zfish   672 FGRTV---ASKTPKCWTGRFLMNLWAIFCLLVLSSYTANLAAVMVGEKTFEEVSGIHDVKLHHPS 733

  Fly   661 TRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSY-AFLMES 724
            ...::|.::..|...:.:.|....::.|..|.:...|        :||..:....... ||:|:.
Zfish   734 LGFRFGTVRESSAEDYVKKSFPEMHEYMRRFNKPTTP--------DGVSTLKTDPPQLDAFIMDK 790

  Fly   725 TSIEYVT--ERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEK 787
            ..::|..  :.:|:|..||.....:.|||..|.|||....::..:.:.:.:|.:.:|..||:|.
Zfish   791 ALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTRNVSEYVSRYKSDGYMDMLHDKWYKV- 854

  Fly   788 RGGGKCRVETSKSSSAANE---LGLANVGGVFVVLMGGMGVACVIAVCE 833
                   |...|...|..|   :|:.:..|:||:|..|:..|.:..:.|
Zfish   855 -------VPCGKRVFAVTETLQMGIQHFSGLFVLLCVGVAGALLTLLGE 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	99/461 (21%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	103/418 (25%)
grin3ba	XP_021323058.1	Periplasmic_Binding_Protein_type1	36..427	CDD:471960	87/426 (20%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	102/415 (25%)
		Lig_chan	618..885	CDD:459656	74/292 (25%)