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Protein Alignment KaiR1D and Gria3

DIOPT Version :9

Sequence 1:	NP_650925.1	Gene:	KaiR1D / 42473	FlyBaseID:	FBgn0038837	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001268858.2	Gene:	Gria3 / 53623	MGIID:	95810	Length:	888	Species:	Mus musculus

Alignment Length:	856	Identity:	331/856 - (38%)
Similarity:	512/856 - (59%)	Gaps:	54/856 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRS-KLVAQIERISPFDSFHAGKRVCGLLN 90
            |:.|.|||||......:..|||.||...|.:::...:. .|...::.:...:||......|...:
Mouse    25 PNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFS 89

  Fly    91 IGVAAIFGPQSSHTASHVQSICDNME----IPHLENRWDYRLRRESCLVNLYPHPNTLSKAYVDI 151
            .||.||||.....:.:.:.|.|..:.    .|......|.:.     ::.:.|   .|..|.:.:
Mouse    90 RGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQF-----VIQMRP---ALKGAILSL 146

  Fly   152 VRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPFPITVR---QLSDSGDYRPLLKQIKNSAEAHI 213
            :.::.|:.|..:|:...|...||.:::|.....:.:|.|   .:.|..::|.:::::....|...
Mouse   147 LGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQEFRRIIEEMDRRQEKRY 211

  Fly   214 VLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLINEK--IVSD 276
            ::||..|||:.:|:|...:|..|..:.|::.:|....:.|:...:||.|||||:::|.:  :|..
Mouse   212 LIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQ 276

  Fly   277 VVRQW-SIDEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPISCDGQS----- 335
            .:::| .:||:....:.| ..::..:||.:||:.:.|:|...| ..|::|:......|..
Mouse   277 FIQRWVRLDEREFPEAKN-APLKYTSALTHDAILVIAEAFRYL-RRQRVDVSRRGSAGDCLANPA 339

  Fly   336 -TWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAGIRKIGTWNSTLPDGINFT 399
             .|..|..:...:|:|:::|:|..|:||..|.||::.:|:.|:..:|.||.|.||       .:.
Mouse   340 VPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWN-------EYE 397

  Fly   400 RTFSQKQQEI---EANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGF 461
            |......|:|   .::.:|:|:||||||.:||.|.|::...|.||:::|||.|||.:||:|.:..
Mouse   398 RFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRI 462

  Fly   462 NYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSIL 526
            .||:.:|.||.||:.:..|..||||:.||:..|||:|:|.||||..||:.:||:.|||:||:||:
Mouse   463 KYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIM 527

  Fly   527 YRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVE----- 586
            .:||.|..|.:||||.||:.::|:.:..||:||||:||::::|:||||  :.:.:.|:..
Mouse   528 IKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW--HLEDNNEEPRDPQSP 590

  Fly   587 ----SQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERM 647
                ::|.:.|.:||::|:.||||||..|::||.|:|.|:|||||||:|||||||||||||||||
Mouse   591 PDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERM 655

  Fly   648 DSPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVA 712
            .|||||||||||||.|.||.|..|||..|||.|||:.|::|||:|:||.|||||.:..:||.||.
Mouse   656 VSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVR 720

  Fly   713 KGKGSYAFLMESTSIEYVTERN-CELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKL 776
            |.||.:|||:|||..||:.:|. |:..:|||.||:|.||:|||..|..||.:|..:|||.|:|.|
Mouse   721 KSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGIL 785

  Fly   777 HILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKV 841
            ..||.|||.:|   |:|..:.|.|....:.|.|:||.|||.:|:||:|:|.::|:.||.:|||
Mouse   786 DKLKNKWWYDK---GECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSR-- 845

  Fly   842 AVEERLSAILN 852
            |..:|:....|
Mouse   846 AESKRMKLTKN 856

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.