Protein Alignment KaiR1D and GluRIID

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_651982.1
• Gene: GluRIID / 44483
• FlyBaseID: FBgn0028422
• Length: 902
• Species: Drosophila melanogaster
• Alignment Length: 837
• Identity: 331/837 - (39%)
• Similarity: 504/837 - (60%)
• Gaps: 53/837 - (6%)

  Fly    30 IKIGGLFHPADDHQELAFRQAVDRINADRSILPRSKLVAQIERISPFDSFHAGKRVCGLLNIGVA 94
            |::|.:...|.|.....|..|:..:|.:..:    .||.:.|:::..:|..|..::|.|:..||.
  Fly    34 IRLGLITDDATDRIRQTFEHAISVVNNELGV----PLVGETEQVAYGNSVQAFAQLCRLMQSGVG 94

  Fly    95 AIFGPQSSHTASHVQSICDNMEIPHLENRWDYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGWKT 159
            |:|||.:.|||||:.:.||:.:||.:.....:....:.  .||:|.|..::.|..|||..:.|..
  Fly    95 AVFGPAARHTASHLLNACDSKDIPFIYPHLSWGSNPDG--FNLHPSPEDIANALYDIVNQFEWSR 157

  Fly   160 FTIIYENNDGIVRLQELLKAHGMTPFPITVRQ--LSDSGDYRPLLKQIKNSAEAHIVLDCSTERI 222
            |...||:.:.:..|..|:..:|:....|.|.:  |:.:|:|:.:|::|:.|.::.||:..||..:
  Fly   158 FIFCYESAEYLKILDHLMTRYGIKGPVIKVMRYDLNLNGNYKSVLRRIRKSEDSRIVVVGSTTGV 222

  Fly   223 HEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLI--NEKIVSDVVRQ--WSI 283
            .|:|:||||:|:|::.::|::.:|:|||.:|:|::|...||||.|:.  :::.|.|::.:  ..:
  Fly   223 AELLRQAQQVGIMNEDYTYIIGNLNLHTFDLEEYKYSEANITGIRMFSPDQEEVRDLMEKLHQEL 287

  Fly   284 DEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHP--ISCDGQ--STWQHGFSLI 344
            .|...:.|.: |.:..|.||.||||.:.|      :|::.:...|  ::|..:  :....|.:..
  Fly   288 GESEPVNSGS-TFITMEMALTYDAVRVIA------ETTKHLPYQPQMLNCSERHDNVQPDGSTFR 345

  Fly   345 NYMKIVEMKGLTNVIKFDHQG-FRTDFMLDIVELTPAGIRKIGTWNSTLPDGINFTRTFSQKQQE 408
            |||:.:|:|..|...:...:| .|..|..|::||..:|:.|:|||.    :|.:|  .|.:..|.
  Fly   346 NYMRSLEIKEKTITGRIYFEGNVRKGFTFDVIELQTSGLVKVGTWE----EGKDF--EFQRPPQA 404

  Fly   409 IEAN------LKNKT-LVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQ 466
            :..|      |.||| :|:.::.:.||....||...|.||:||:||.||||.|::..||||:..:
  Fly   405 VNFNDIDDGSLVNKTFIVLISVATKPYASLVESIDTLIGNNQFQGYGVDLIKELADKLGFNFTFR 469

  Fly   467 LVPDG--SYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRK 529
               ||  .|||.||.|...:||::|::|.||||||.|||||.|||:.:||:.||||||::|||.|
  Fly   470 ---DGGNDYGSFNKTTNSTSGMLKEIVEGRADLAITDLTITSEREEVIDFSIPFMNLGIAILYVK 531

  Fly   530 PIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEW--PAYTDAHGEKVESQFTLL 592
            |.|.||.||||:.|.|.:||:|:..||||||:..||:.:.:|.||  |.......|::|:|||:.
  Fly   532 PQKAPPALFSFMDPFSSEVWLYLGIAYLGVSLCFFIIGRLSPIEWDNPYPCIEEPEELENQFTIN 596

  Fly   593 NCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDL 657
            |.:||..|:|:|||.:..|||||||.::.|||||||||:||||||||||||:|...|||.|.:||
  Fly   597 NSLWFTTGALLQQGSEIAPKALSTRTISAIWWFFTLIMVSSYTANLAAFLTIENPTSPINSVKDL 661

  Fly   658 A-KQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFL 721
            | .:..::|||.:.|||..||..|:...|.:|..:: :|.|.:...:|.:||::|..|. .||||
  Fly   662 ADNKDDVQYGAKRTGSTRNFFSTSEEPIYIKMNEYL-NAHPEMLMENNQQGVDKVKSGT-KYAFL 724

  Fly   722 MESTSIEYVTERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKE 786
            |||||||:.|.|.|.||:||..||.|.||||...|.|||...|..:|:|||:|.|..||.|||.|
  Fly   725 MESTSIEFNTVRECNLTKVGDPLDEKGYGIAMVKNWPYRDKFNKALLELQEQGVLARLKNKWWNE 789

  Fly   787 KRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAV---CEFVWKSRK 840
            . |.|.|..::  .....:|||:.|:.|::|||:.|..::.:|::   |.||:|..|
  Fly   790 V-GAGVCSAKS--DDDGPSELGVDNLSGIYVVLVIGSIISIIISILCWCYFVYKKAK 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	112/379 (30%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	194/375 (52%)
GluRIID	NP_651982.1	PBP1_iGluR_Kainate	35..400	CDD:380605	113/383 (30%)
		PBP2_iGluR_Kainate	417..788	CDD:270432	194/375 (52%)
		Lig_chan	547..819	CDD:459656	134/276 (49%)