Protein Alignment KaiR1D and Ir93a

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Alignment Length: 965
• Identity: 194/965 - (20%)
• Similarity: 380/965 - (39%)
• Gaps: 226/965 - (23%)

  Fly     1 MRSSGVLVLPLLLLQL-ILNCRKAQSLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRS 64
            ||.|..|:| |..||| ||...:|......:..........||:.:.       ::.:..:....
  Fly     6 MRPSACLLL-LAGLQLSILVPTEANDFSSFLSANASLAVVVDHEYMT-------VHGENILAHFE 62

  Fly    65 KLVAQIERIS--------PFDSFHAGKRVCGLLNIGVAAI----------FGPQSSHTASHVQSI 111
            |:::.:.|.:        .:.|::|.:    |....:|||          |...:..|:..:.:|
  Fly    63 KILSDVIRENLRNGGINVKYFSWNAVR----LKKDFLAAITVTDCENTWNFYKNTQETSILLIAI 123

  Fly   112 CDN----------MEIPHLENRWDYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGWKTFTI---- 162
            .|:          :.:|.:||..::              |..:..|.|..:.:  |||..:
  Fly   124 TDSDCPRLPLNRALMVPIVENGDEF--------------PQLILDAKVQQILN--WKTAVVFVDQ 172

  Fly   163 -IYENNDGIVR--LQELLKAHGMTPFPITVRQLSDS--------------GDYRPLLKQIKNSAE 210
             |.|.|..:|:  :.|.:..| :||..:.:.:::||              ..:.|  |:.:...:
  Fly   173 TILEENALLVKSIVHESITNH-ITPISLILYEINDSLRGQQKRVALRQALSQFAP--KKHEEMRQ 234

  Fly   211 AHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDL---------HTVNLDEFRYGGTNITGF 266
            ..:|:....|.|.|:   |:.:.|....:.:::..||:         .|:||||    |.|| .|
  Fly   235 QFLVISAFHEDIIEI---AETLNMFHVGNQWMIFVLDMVARDFDAGTVTINLDE----GANI-AF 291

  Fly   267 RLINEKIVSDVVRQWSID------EKGLLRSANLTTVRSETAL------MYDAVHLF--AKALHD 317
            .| ||   :|...|.|::      ...|:.:.:..||..|:..      .::|:...  .|....
  Fly   292 AL-NE---TDPNCQDSLNCTISEISLALVNAISKITVEEESIYGEISDEEWEAIRFTKQEKQAEI 352

  Fly   318 LDTSQQIDIHPISCDGQSTWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAGI 382
            |:..::.......|...:.|:.. :.|.:.|..|.:...:..:.|.:....:|:
  Fly   353 LEYMKEFLKTNAKCSSCARWRVE-TAITWGKSQENRKFRSTPQRDAKNRNFEFI----------- 405

  Fly   383 RKIGTWNSTLPDGINFTRTFSQKQQE-----IEANLKNKTLVVTTILSNPYCMRKESAIPLSGND 442
             .||.|...|    .|.      .||     ||.:.:|.|:.:.|:.:.|:.:       |:.|.
  Fly   406 -NIGYWTPVL----GFV------CQELAFPHIEHHFRNITMDILTVHNPPWQI-------LTKNS 452

  Fly   443 -----QFEGYAVDLIHEISKSLGFNYKI----------QLVPDGSYGSLNKLTGEWNGMIR---- 488
                 :.:|..::::.|:|::|.|:|.:          .|.........::|.|.....|.
  Fly   453 NGVIVEHKGIVMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAGGNESDELVGSMTFRIPYRVV 517

  Fly   489 ELLEQRADLAIADLTITFE--REQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIY 551
            |:: |.....||.:..|.|  .::..::|.|......|.:.||| .:...::.|.:|.:::.|..
  Fly   518 EMV-QGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKP-DEVSRIYLFTAPFTVETWFC 580

  Fly   552 MATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGCDFLPKALST 616
            :....|..:..|:.:.:..|.:        ..::....|:.:|.|:..|:|:|||..:||.|.|.
  Fly   581 LMGIILLTAPTLYAINRLAPLK--------EMRIVGLSTVKSCFWYIFGALLQQGGMYLPTADSG 637

  Fly   617 RMVAGIWWFFTLIMISSYTANLAAFLTVERMD------SPIESAEDLAKQTRIKYGALKGGSTAA 675
            |:|.|.||...::::::|..||.||||..:..      :.:|..:|:     ::|| |:.|:
  Fly   638 RLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDI-----VQYG-LRNGT--- 693

  Fly   676 FF-RDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIE----------- 728
            || |..:.:|.:....::|.|:  ::.::..|.:|.|.:|        |..:|:
  Fly   694 FFERYVQSTTREDFKHYLERAK--IYGSAQEEDIEAVKRG--------ERINIDWRINLQLIVQR 748

  Fly   729 -YVTERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWK-EKRGGG 791
             :..|:.|...........:...:..|..|.|...:|..|..:...|.:.    :|.: .....|
  Fly   749 HFEREKECHFALGRESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIE----RWHQMNLPSAG 809

  Fly   792 KCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKVAVEER 846
            ||..::::.....:::.:.::.|.|:||:.|..:|.:| ||...|..|..|..:|
  Fly   810 KCNGKSAQRQVTNHKVNMDDMQGCFLVLLLGFTLALLI-VCGEFWYRRFRASRKR 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	77/440 (18%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	85/409 (21%)
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:473866	66/293 (23%)
		Lig_chan	574..836	CDD:459656	60/292 (21%)