Protein Alignment KaiR1D and Nmdar1

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 945
• Identity: 231/945 - (24%)
• Similarity: 394/945 - (41%)
• Gaps: 187/945 - (19%)

  Fly     6 VLVLPLLLLQLIL--------NCRKAQSLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILP 62
            |...||..|.::|        ....|...|....|||:...:|..:.  |...:..:|.|:..:|
  Fly     7 VFCRPLFGLAIVLLVAPIDAAQRHTASDNPSTYNIGGVLSNSDSEEH--FSTTIKHLNFDQQYVP 69

  Fly    63 RS-------------------------------KLVAQIERISPFDSFHAGKRVCGLLNIGVAAI 96
            |.                               .:|...|:.|...|..|.....|..:|.|..|
  Fly    70 RKVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGI 134

  Fly    97 FGPQSSHTASHVQSICDNMEIPHLENRWDYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGWKTFT 161
                ||..|:....   |:.:..|..            |..|.|.   :..:::::.|:.:....
  Fly   135 ----SSRDAAFSDK---NIHVSFLRT------------VPPYYHQ---ADVWLEMLSHFAYTKVI 177

  Fly   162 IIYENN-DGIVRLQELLKAHGMTPFPITVRQLSDSGDYRPLLKQI----------------KNSA 209
            ||:.:: ||...|..         |..|.:...|..|.|..::.|                ..:|
  Fly   178 IIHSSDTDGRAILGR---------FQTTSQTYYDDVDVRATVELIVEFEPKLESFTEHLIDMKTA 233

  Fly   210 EAHI-VLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLINEKI 273
            ::.: ::..|||....:.:.|.:..|..:.|.::||...|.:.|..:      .:.|.:|  |..
  Fly   234 QSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPD------GVLGLQL--EHA 290

  Fly   274 VSDVVRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPISC-DGQSTW 337
            .||         ||.:|               |:|::.|.|:.::.:::.|...|..| |....|
  Fly   291 HSD---------KGHIR---------------DSVYVLASAIKEMISNETIAEAPKDCGDSAVNW 331

  Fly   338 QHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTP------AGIRKIGTWNSTLPDGI 396
            :.|..|..|:|...:.|.|..:.||..|.|.....|::.:..      .|.....:..:.:...|
  Fly   332 ESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRI 396

  Fly   397 NFTRTF--SQKQQEIEANLKNKTLVVTTILSNPY------------CMRKESAIPLSGN-----D 442
            |.:...  .:::::.|..:....|.:.||...|:            |...|...||..|     :
  Fly   397 NDSEIIWPGKQRRKPEGIMIPTHLRLLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNSDATAN 461

  Fly   443 QF--EGYAVDLIHEISKSLGFNYKIQLVPDGSYGS--LNKLTG------EWNGMIRELLEQRADL 497
            :|  .||.:||:.|:||.:.|.|.:.|.|||.:|.  |...||      ||.|:|.||:.:|||:
  Fly   462 EFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADM 526

  Fly   498 AIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVL 562
            .:|.|||..||.:.::|:.||...|::||.:|| .:...|.|||.|.|..:||.:..:...|:::
  Fly   527 IVAPLTINPERAEYIEFSKPFKYQGITILEKKP-SRSSTLVSFLQPFSNTLWILVMVSVHVVALV 590

  Fly   563 LFILAKFTPYE--WPAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGC-DFLPKALSTRMVAGIWW 624
            |::|.:|:|:.  ..:::|::.||.   ..|.:.:|||.|.|:..|. :..|::.|.|::..:|.
  Fly   591 LYLLDRFSPFGRFKLSHSDSNEEKA---LNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWA 652

  Fly   625 FFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQT---RIKYGALKGGSTAAFFRDSKISTYQ 686
            .|.:|:::||||||||||.:||..:.:....|...:.   .:....:||.|...:||  :.....
  Fly   653 GFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFR--RQVELS 715

  Fly   687 RMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVGGMLDTKSYGI 751
            .|:..||:..    .|:..:.::.|.||| ..||:.:|:.:||...::|||...|.:.....|||
  Fly   716 NMYRTMEANN----YATAEQAIQDVKKGK-LMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGI 775

  Fly   752 ATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVF 816
            .....||:..|:...||:..|.|.:..|..:|.........|.:    .....|.|||.|:.|||
  Fly   776 GLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCEL----FEKTPNTLGLKNMAGVF 836

  Fly   817 VV----LMGGMGVACVIAVCEFVWKSRKVAVEERL 847
            ::    :.||:|    :.:.|.::|..:|..::||
  Fly   837 ILVGVGIAGGVG----LIIIEVIYKKHQVKKQKRL 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	80/424 (19%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	126/402 (31%)
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	80/432 (19%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	126/411 (31%)
		CaM_bdg_C0	854..882	CDD:402271	4/14 (29%)