Protein Alignment KaiR1D and clumsy

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Alignment Length: 858
• Identity: 374/858 - (43%)
• Similarity: 536/858 - (62%)
• Gaps: 39/858 - (4%)

  Fly    11 LLLLQLILNCRKAQSLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRS-KLVAQIERIS 74
            |:.|.::.:..::|.:     :|.:|....|..|:|||.||||.|    ||.|: :||..:...:
  Fly    11 LIALPVLADIDRSQFM-----VGSIFTSDKDESEIAFRTAVDRAN----ILERNVELVPIVVYAN 66

  Fly    75 PFDSFHAGKRVCGLLNIGVAAIFGPQSSHTASHVQSICDNMEIPHLENRW-------DYRLRRES 132
            ..|||...|.||.|::.||.|||||.:..::..:.||||.::|||:...|       |    ||.
  Fly    67 TDDSFIMEKMVCNLISQGVIAIFGPSTGSSSDIIASICDTLDIPHIVYDWIPNESIPD----REH 127

  Fly   133 CLVNLYPHPNT--LSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPFPITVRQLSDS 195
            ..:.|..||:.  ||:...:||:.:.|::||::||.:..:.:||::|:.......|.||:||...
  Fly   128 STMTLNVHPDNLLLSQGLAEIVQSFAWRSFTVVYETDKELQQLQDILQVGEPISNPTTVKQLGPG 192

  Fly   196 GDYRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGG 260
            .|:||.||:||.|.:..::|.|:.:.:.::|:||.::.|:.:|.|..:..||.|:::..|.....
  Fly   193 DDHRPFLKEIKLSTDNCLILHCAPDNLLKILQQANELKMLGEYQSVFIPLLDTHSIDFGELSGVE 257

  Fly   261 TNITGFRLI--NEKIVSDVVRQWSIDEK--GLLRSANLTTVRSETALMYDAVHLFAKALHDLDTS 321
            .|||..||:  ::..|.:||..|...||  |.....:...|:|:..|:.|||.||:|.|.:|...
  Fly   258 ANITTVRLMDPSDFHVKNVVHDWEEREKREGRYFKVDPNRVKSQMILLNDAVWLFSKGLTELGIF 322

  Fly   322 QQIDIHPISCDGQSTWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAGIRKIG 386
            :::....:.|..:..|..|..:|.::|....:..|..|.|:..|.|:.|.|..:||...|...:.
  Fly   323 EELTAPDLECRRKKPWPFGKRIIEFIKARSEETSTGRIDFNENGQRSFFTLRFMELNSDGFLDLA 387

  Fly   387 TWNSTLPDGINFTRTFSQKQQEIEANLKNKTLVVTTILSNPYCMRKESAIP-----LSGNDQFEG 446
            ||:..  :|::......:.::.:...|.|||.:|::.|..|:...:|   |     |:||.::||
  Fly   388 TWDPV--NGLDVLNDDEESEKRVGQKLSNKTFIVSSRLGAPFLTLRE---PQEGEILTGNSRYEG 447

  Fly   447 YAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQA 511
            |::|||:||:|.|.|.::.::.|||.||:|||:|..|:|::|:|::..|||.|.|||:|..|.||
  Fly   448 YSIDLINEIAKMLNFKFEFRMSPDGKYGALNKVTQTWDGIVRQLIDGNADLGICDLTMTSSRRQA 512

  Fly   512 VDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWP- 575
            ||||.|||.||:|||:.||...|.:|||||||.||||||||.:|||.:|:|||.||:..|.:|.
  Fly   513 VDFTPPFMTLGISILFSKPPTPPTDLFSFLSPFSLDVWIYMGSAYLFISLLLFALARMAPDDWEN 577

  Fly   576 AYTDAHGEKVESQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAA 640
            .:.....|:||:.::::|..|.:|||||.||||.||||.|||:|.|:||||.|:|::||||||||
  Fly   578 PHPCKEPEEVENIWSIMNTTWLSIGSLMGQGCDILPKAASTRLVTGMWWFFALMMLNSYTANLAA 642

  Fly   641 FLTVERMDSPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNG 705
            |||..|..:.|.||||||.|::|||||:.||||..|||||..||||:||:.||||.|||||.:|.
  Fly   643 FLTNSRQANSINSAEDLAAQSKIKYGAMAGGSTMGFFRDSNFSTYQKMWTAMESASPSVFTKTND 707

  Fly   706 EGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKL 770
            ||||||.|||..||||||||::||..||.|:|.|:||.||.||||||.|.|||||..|::.:|||
  Fly   708 EGVERVQKGKNLYAFLMESTTLEYNVERKCDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLKL 772

  Fly   771 QEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFV 835
            .|.|:|..||.|||||..|||.|. ::.:......||||.||||||:||..|:..|.|:...||:
  Fly   773 GELGQLAELKRKWWKEMHGGGNCE-KSDEDGGDTPELGLENVGGVFLVLGLGLLSAMVLGCTEFL 836

  Fly   836 WKSRKVAVEERLS 848
            |..:.||:||::|
  Fly   837 WNVKSVAIEEKIS 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	123/382 (32%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	217/375 (58%)
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	27..397	CDD:380605	123/379 (32%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	217/375 (58%)