Protein Alignment KaiR1D and Ir25a

DIOPT Version :9

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 870
• Identity: 237/870 - (27%)
• Similarity: 394/870 - (45%)
• Gaps: 169/870 - (19%)

  Fly    77 DSFHAGKRVCGLL-----NIGVAAIFGPQSSH----------TASHVQSICDNMEIPHLE----- 121
            ||..|.|....:|     |....:|...|:.|          .:..|:|....:.:|.:.
  Fly    73 DSIEANKSDAKVLLEAICNKYATSIEKKQTPHLILDTTKSGIASETVKSFTQALGLPTISASYGQ 137

  Fly   122 ----NRW-DYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHG 181
                .:| |....::..|:.:.|..:.:.:|...||.|.......|:|:::        .:..|
  Fly   138 QGDLRQWRDLDEAKQKYLLQVMPPADIIPEAIRSIVIHMNITNAAILYDDS--------FVMDH- 193

  Fly   182 MTPFPITVRQLSDSGDYRPLLKQIKNSAEAHIVL----DCSTERIHEVLK--------------- 227
                           .|:.||:.|:.   .|::.    |...||..::.|
  Fly   194 ---------------KYKSLLQNIQT---RHVITAIAKDGKREREEQIEKLRNLDINNFFILGTL 240

  Fly   228 QAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLINEKIVSDVVRQWSIDEKGLLRSA 292
            |:.::.:.|...:|...:...|.:..:|............:..:.:.....|    |..||||:.
  Fly   241 QSIRMVLESVKPAYFERNFAWHAITQNEGEISSQRDNATIMFMKPMAYTQYR----DRLGLLRTT 301

  Fly   293 -NLTTVRSETALMYDAVHLFAKALHDLDTSQQI--------DIHPISCD---GQSTWQHGFSLIN 345
             ||......::..|     |..||....|.:::        |:..::||   |.:|.|....|.:
  Fly   302 YNLNEEPQLSSAFY-----FDLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRD 361

  Fly   346 YM-KIVEMKGLTNVIKFD-----------HQGFRTDFMLDIVEL---TPAGIRKIGTWNSTLPDG 395
            |. ||.|.   |:...||           |...:.:..::::::   :....:.||.|.|    |
  Fly   362 YFTKITEP---TSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKSIGKWIS----G 419

  Fly   396 INFTRTFSQKQQEIEANLKNKTLV-VTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSL 459
            :|  .....|.:|...||...|:. :.|::..|:.||.|:| |..    ::||.:|||:||:..:
  Fly   420 LN--SELIVKDEEQMKNLTADTVYRIFTVVQAPFIMRDETA-PKG----YKGYCIDLINEIAAIV 477

  Fly   460 GFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNL-GV 523
            .|:|.||.|.||.:|:::: .|:|||::::|::::||:.:..:::..|||..:|||.|:.:| |:
  Fly   478 HFDYTIQEVEDGKFGNMDE-NGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGI 541

  Fly   524 SILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVES- 587
            :|:.::| ..|.:||.||:.|..:||:.:..||...|.|::|..:::||.:....:.:.:..|.
  Fly   542 TIMMQRP-SSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKR 605

  Fly   588 QFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIE 652
            :|.|..|:||.:.||..||....||.||.|:||..||.|..|:|:||||||||||||.|:|:|:|
  Fly   606 EFNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVE 670

  Fly   653 SAEDLAKQTRIKYGALKGGSTAAFF--------------RD------------SKIST------- 684
            |.:|||||.:|.|..|.|.|...:|              :|            ||::.
  Fly   671 SLDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSD 735

  Fly   685 -YQRMWSFMESARPSVFTASNGEGVERVAKGKGS--YAFLMESTSIEYVTERNCELTQVGGMLDT 746
             |.:||..|:.|:   ..|:..|.|.||.....:  :|||.::|.|.|:...||:|..||.....
  Fly   736 KYTKMWQAMQEAK---LPATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTNCDLQVVGEEFSR 797

  Fly   747 KSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLAN 811
            |.|.||....|..:...|:.||.|..:.:|..||.||||......||    .|....::.:.:.|
  Fly   798 KPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKC----DKPEDQSDGISIQN 858

  Fly   812 VGGVFVVLMGGMGVACVIAVCEFVW 836
            :||||:|:..|:|:||:..|.|:.|
  Fly   859 IGGVFIVIFVGIGMACITLVFEYWW 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..397	CDD:107377	70/390 (18%)
		ANF_receptor	42..378	CDD:279440	65/371 (18%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:304360	144/408 (35%)
		Lig_chan	547..823	CDD:278489	108/312 (35%)
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	71/397 (18%)
		PBP2_iGluR_putative	438..836	CDD:270435	144/407 (35%)
		Lig_chan	565..870	CDD:278489	108/311 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I1556
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.960