Protein Alignment KaiR1D and Nmdar2

DIOPT Version :9

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Alignment Length: 863
• Identity: 190/863 - (22%)
• Similarity: 333/863 - (38%)
• Gaps: 201/863 - (23%)

  Fly    89 LNIGVAAI--------FGPQSSHTASHVQSICDNMEIPHLENRW-------DYRLRRESCLVNLY 138
            |.:.|:||        || .|:.:|.:...:...:.||.:.  |       :.|..:.:..:.|.
  Fly   172 LRVNVSAILYMMNNEQFG-HSTASAQYFLQLAGYLGIPVIS--WNADNSGLERRASQSTLQLQLA 233

  Fly   139 PHPNTLSKAYVDIVRHWGWKTFTIIYENNDG-----------IVRLQELLKAHGMTPFPITVRQL 192
            |.....|.|.:.|:..:.|..|:::.....|           :..:||..|...:.  .|.|.:.
  Fly   234 PSIEHQSAAMLSILERYKWHQFSVVTSQIAGHDDFVQAVRERVAEMQEHFKFTILN--SIVVTRT 296

  Fly   193 SDSGDYRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVT-----SLDLHTVN 252
            ||      |::.:.:.|...::....||.| .:|:.|:::.:..:.:.::|:     ..|.|:
  Fly   297 SD------LMELVNSEARVMLLYATQTEAI-TILRAAEEMKLTGENYVWVVSQSVIEKKDAHS-- 352

  Fly   253 LDEFRYGGTNI----TGFRLINEKIVSDVVRQWSIDEKGLL-----RSANLTTVRSETALMYDAV 308
              :|..|...:    :...|:||  :|:.::.:|...:..|     |...|||
  Fly   353 --QFPVGMLGVHFDTSSAALMNE--ISNAIKIYSYGVEAYLTDPANRDRRLTT------------ 401

  Fly   309 HLFAKALHDLDTSQQIDIHPISC--DGQSTWQHGFSLINYMKIVEMKGLTNV--IKFDHQGFRTD 369
                              ..:||  :|:..|.:|.....|::.|.::|..|.  |:|...|....
  Fly   402 ------------------QSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRS 448

  Fly   370 FMLDIVELTPAGIRK------IGTWNS------------------TLPDGINFTRTFSQKQQEIE 410
            ..|.|:.|.|:...|      ||.|.|                  ..|.|:  ...|..|
  Fly   449 AELKIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAPPQGV--PEKFHLK----- 506

  Fly   411 ANLKNKTLVVTTILSNPYCMRKESAIPLSG-----------------------------NDQF-- 444
                     :|.:...|| :....|.|:||                             |:.|
  Fly   507 ---------ITFLEEAPY-INLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQ 561

  Fly   445 --EGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFE 507
              .|:.:||:.:.::.|||.|::..|.||.:|:|.  .|:|||:|.:|:.::.|:.:..|.|..|
  Fly   562 CCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLE--NGKWNGLIADLVNRKTDMVLTSLMINTE 624

  Fly   508 REQAVDFTTPFMNLGVSILY--RKPIKQPPNLFSFLSPLSLDVWIYMA-TAYLGVSVLLFILAKF 569
            ||..|||:.|||..|::|:.  |..|..|.   :||.|.....|:.:. .|....:.::|:....
  Fly   625 REAVVDFSEPFMETGIAIVVAKRTGIISPT---AFLEPFDTASWMLVGIVAIQAATFMIFLFEWL 686

  Fly   570 TP--YEWPAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGCDF-LPKALSTRMVAGIWWFFTLIMI 631
            :|  |:...|.. :......:|:|....|.....|.|..... .|:..::|.:..:|..|.::.:
  Fly   687 SPSGYDMKLYLQ-NTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFL 750

  Fly   632 SSYTANLAAFLTVERMDSPIESAED------LAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWS 690
            :.||||||||:.............|      .:.:...|:|.:....|     ||.|..|   ::
  Fly   751 AIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHT-----DSTIHKY---FN 807

  Fly   691 FMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVT--ERNCELTQVGGMLDTKSYGIAT 753
            .|.:........|..:||..|..|... :|:.:.|.::|:.  :.:|.|..||.......||:|.
  Fly   808 VMHNYMRQYNKTSVADGVAAVLNGNLD-SFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAF 871

  Fly   754 PPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVV 818
            ..||.|....|..:|:.:..|.|..|:..|..     |.||....:..| ::.|.|......|::
  Fly   872 SRNSKYVQMFNKRLLEFRANGDLERLRRYWMT-----GTCRPGKQEHKS-SDPLALEQFLSAFLL 930

  Fly   819 LMGGMGVACVIAVCEFVW 836
            ||.|:.:|.::.:.|.|:
  Fly   931 LMAGILLAALLLLLEHVY 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..397	CDD:107377	72/375 (19%)
		ANF_receptor	42..378	CDD:279440	63/332 (19%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:304360	103/416 (25%)
		Lig_chan	547..823	CDD:278489	65/287 (23%)
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	70/365 (19%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	107/440 (24%)
		Lig_chan	665..928	CDD:278489	62/278 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I1556
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.960