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Protein Alignment KaiR1D and Grik1

DIOPT Version :9

Sequence 1:	NP_650925.1	Gene:	KaiR1D / 42473	FlyBaseID:	FBgn0038837	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001104587.1	Gene:	Grik1 / 29559	RGDID:	2732	Length:	949	Species:	Rattus norvegicus

Alignment Length:	886	Identity:	424/886 - (47%)
Similarity:	583/886 - (65%)	Gaps:	69/886 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRSSGVLVLP-----------LLLLQLILNCRKAQSLPDIIKIGGLFHPADDH----QELAFRQA 50
            |..|.||:.|           |..|..||    .|:.|.:::|||:|...::.    :||||:.|
  Rat     1 MERSTVLIQPGLWTRDTSWTLLYFLCYIL----PQTSPQVLRIGGIFETVENEPVNVEELAFKFA 61

  Fly    51 VDRINADRSILPRSKLVAQIERISPFDSFHAGKRVCGLLNIGVAAIFGPQSSHTASHVQSICDNM 115
            |..||.:|:::|.:.|...|:||:.||||.|.:|.|..|.:||||:|||..|.:.|.|||||:.:
  Rat    62 VTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNAL 126

  Fly   116 EIPHLENRWDYRL--RRESCLVNLYPHPNTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLK 178
            |:||::.||.:..  .|:...:||||....:|:|.:|:|.::.|||.|::||::.|::|||||:|
  Rat   127 EVPHIQTRWKHPSVDSRDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIK 191

  Fly   179 AHGMTPFPITVRQLSDSG-DYRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYL 242
            |.......|.:|||..:. |.:||||::|.|.|.:::.|||.|...|:|||...:|||::|:.|.
  Rat   192 APSRYNIKIKIRQLPPANKDAKPLLKEMKKSKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYF 256

  Fly   243 VTSLDLHTVNLDEFRYGGTNITGFRLIN--EKIVSDVVRQWSID--------EKGLLRSANLTTV 297
            .|:|||..::|:.:||.|.|:|||||:|  ...||.::.:||::        |.||| ...:||
  Rat   257 FTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLL-DGMMTT- 319

  Fly   298 RSETALMYDAVHLFAKALHDLDTSQQIDIHPISCDGQSTWQHGFSLINYMKIVEMKGLTNVIKFD 362
              |.|||||||::.|.|.|   .:.|:.:..:.|.....|:.|...:|.:|.....|||..|.|:
  Rat   320 --EAALMYDAVYMVAIASH---RASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGRITFN 379

  Fly   363 H-QGFRTDFMLDIVELTPAGI---------------RKIGTWNSTLPDGINFTRTFSQKQQEIEA 411
            . .|.|.||.|||:.|...|.               :|||.|||.  .|:|.|.....:...|..
  Rat   380 KTDGLRKDFDLDIISLKEEGTEKASGEVSKHLYKVWKKIGIWNSN--SGLNMTDGNRDRSNNITD 442

  Fly   412 NLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVPDGSYGSL 476
            :|.|:||:|||||..||.|.::|..||.|||:||||.:||:.|:|..|||.|.::|||||.||:.
  Rat   443 SLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQ 507

  Fly   477 NKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFL 541
            |. .||||||::||::.|||||:|.||||:.||:.:||:.|||.||:|||||||....|.:||||
  Rat   508 ND-KGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFL 571

  Fly   542 SPLSLDVWIYMATAYLGVSVLLFILAKFTPYEW--PAYTDAHGEKVESQFTLLNCMWFAIGSLMQ 604
            :|||.|:|:|:..|.||||.:||::|:||||||  |...:...:.||:.|||||..||.:|:|||
  Rat   572 NPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQ 636

  Fly   605 QGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTRIKYGALK 669
            ||.:.:|||||||:|.|||||||||:|||||||||||||||||:|||:||:||||||:|:|||::
  Rat   637 QGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVR 701

  Fly   670 GGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERN 734
            .|||..||:.||||||::||:||.|.:.|....::.||::||.  ...||.|||||||||||:||
  Rat   702 DGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVL--TTDYALLMESTSIEYVTQRN 764

  Fly   735 CELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSK 799
            |.|||:||::|:|.||:.||..||||..|...||:||||||||::|.|||   ||.| |..|.||
  Rat   765 CNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWW---RGNG-CPEEDSK 825

  Fly   800 SSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRK 840
            .:||   ||:.|:||:|:||..|:.::..:|:.||::||||
  Rat   826 EASA---LGVENIGGIFIVLAAGLVLSVFVAIGEFLYKSRK 863

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.