Protein Alignment KaiR1D and GRIN2C

DIOPT Version :9

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_016880033.1
• Gene: GRIN2C / 2905
• HGNCID: 4587
• Length: 1337
• Species: Homo sapiens
• Alignment Length: 878
• Identity: 189/878 - (21%)
• Similarity: 350/878 - (39%)
• Gaps: 206/878 - (23%)

  Fly    84 RVCGLLNIGVAAIFGPQSSHTASHVQSIC--DNMEIPHLENRWDYRLRRESCLVNLYPH------ 140
            ::||||.              |:||..|.  ||::...:....|:        ::...|
Human   155 QICGLLG--------------AAHVHGIVFEDNVDTEAVAQILDF--------ISSQTHVPILSI 197

  Fly   141 ---------PNTLSKAYVD--------------IVRHWGWKTFTIIYENNDGIVRLQELLKAHGM 182
                     |.....|::.              ::..:.|..|.:|...:.|          |.:
Human   198 SGGSAVVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPG----------HAL 252

  Fly   183 TPFPITVRQLSDS-----------------GDYRPLLKQIKNSAEAHI-VLDCSTERIHEVLKQA 229
              |...||.::|:                 |..|...:::....:|.: |..||.|....:..:|
Human   253 --FLEGVRAVADASHVSWRLLDVVTLELGPGGPRARTQRLLRQLDAPVFVAYCSREEAEVLFAEA 315

  Fly   230 QQIGMMSDYHSYLVTSLDLHTVNLD--EFRYGGTNITGFRLINEKIVSDVVRQWSIDEKGLLRSA 292
            .|.|::...|.:||.:|.|.:.:..  .|..|             ::|.|...|.:.    ||.
Human   316 AQAGLVGPGHVWLVPNLALGSTDAPPATFPVG-------------LISVVTESWRLS----LRQ- 362

  Fly   293 NLTTVRSETALMYDAVHLFAKALHDLDT-SQQIDIH--PISCDGQSTWQHGFSLINYMKIVEMKG 354
               .||...|::....|.:.:....|.. :....:|  |:|...::.::|   |:|    |..:|
Human   363 ---KVRDGVAILALGAHSYWRQHGTLPAPAGDCRVHPGPVSPAREAFYRH---LLN----VTWEG 417

  Fly   355 LTNVIKFDHQGFRTDFMLDIVELTPAGI-RKIGTWNSTLPDGINFTR--TFSQKQQEIEANLKNK 416
              ....|...|:.....:.::.|....: ..:|.|.    .|:.:.:  .:.:....::..:.::
Human   418 --RDFSFSPGGYLVQPTMVVIALNRHRLWEMVGRWE----HGVLYMKYPVWPRYSASLQPVVDSR 476

  Fly   417 TLVVTTILSNPY------------CM------RKESAIPLSGNDQ-------FEGYAVDLIHEIS 456
            .|.|.|:...|:            |:      |::|....|..|.       .:|:.:|::.:::
Human   477 HLTVATLEERPFVIVESPDPGTGGCVPNTVPCRRQSNHTFSSGDVAPYTKLCCKGFCIDILKKLA 541

  Fly   457 KSLGFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNL 521
            :.:.|:|.:.||.:|.:|  .::.|.|||||.|:..:|||:||..|||..||.:.|||:.||:..
Human   542 RVVKFSYDLYLVTNGKHG--KRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVET 604

  Fly   522 GVSILY-RKPIKQPPNLFSFLSPLSLDVWIYMATAYLG-VSVLLFILAKFTPYEWPAYTDAHGEK 584
            |:|::. |......|:  :||.|.|..||:.|....|. |::.:|:...|:|..:........:.
Human   605 GISVMVARSNGTVSPS--AFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTRGKKS 667

  Fly   585 VESQFTLLNCMWFAIGSLMQQGCDF-LPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMD 648
            ....||:...:|.....:....... .|:..:::::..:|.||.:|.::|||||||||:..|:..
Human   668 GGPAFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYI 732

  Fly   649 SPIESAED-------------LAKQT--------------RIKYGALKGGSTAAFFRDSKISTYQ 686
            ..:....|             .|.:|              ..::|.:..|||....|.:....:.
Human   733 DTVSGLSDKKSLHLENTGVAWTAFKTFCSDYFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHT 797

  Fly   687 RMWSF----MESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVT--ERNCELTQVGG--M 743
            .|..|    :|.|..|:...|..:.|.|...     ||:.::..:.|:.  :..|:|..:|.  :
Human   798 HMVKFNQRSVEDALTSLKMGSEAQPVPRKLD-----AFIYDAAVLNYMAGKDEGCKLVTIGSGKV 857

  Fly   744 LDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELG 808
            ..|..||||...:|.::.||:..:|:...:|:...|:|.|.     .|.|:.|  |:...:::|.
Human   858 FATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVWL-----SGICQNE--KNEVMSSKLD 915

  Fly   809 LANVGGVFVVLMGGMGVACVIAVCEFV--WKSR 839
            :.|:.|||.:|:..||:|.::...|.:  ||.|
Human   916 IDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLR 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..397	CDD:107377	64/367 (17%)
		ANF_receptor	42..378	CDD:279440	60/347 (17%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:304360	108/432 (25%)
		Lig_chan	547..823	CDD:278489	71/312 (23%)
GRIN2C	XP_016880033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810