Protein Alignment KaiR1D and GRIN2A

DIOPT Version :9

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_016878661.1
• Gene: GRIN2A / 2903
• HGNCID: 4585
• Length: 1516
• Species: Homo sapiens
• Alignment Length: 915
• Identity: 220/915 - (24%)
• Similarity: 365/915 - (39%)
• Gaps: 213/915 - (23%)

  Fly     7 LVLPLLLLQLILNCRKAQSL----PDII---KIGGLFHPADDHQELAFRQAVDRINADRSILPRS 64
            |.|.:.::.|::|....:||    .|::   :|.||....|..|| |..|.:|.|::...:
Human   115 LPLDVNVVALLMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQE-AVAQMLDFISSHTFV---- 174

  Fly    65 KLVAQIERISPFDSFHAGKRVCGLLNIGVAAIFGPQSSHTASHVQ---SICDNMEIPHLENRWDY 126
                      |....|.|           |::.......|::..|   ||.....: .|:...||
Human   175 ----------PILGIHGG-----------ASMIMADKDPTSTFFQFGASIQQQATV-MLKIMQDY 217

  Fly   127 RLRRESCLVNLYPH--------PNTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMT 183
            .....|.:..::|.        ..|:..::|      ||        :...::.|.        |
Human   218 DWHVFSLVTTIFPGYREFISFVKTTVDNSFV------GW--------DMQNVITLD--------T 260

  Fly   184 PFPITVRQLSDSGDYRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDL 248
            .|.....|:.        ||:|.:|.   |:|.||.:....:|.:|:.:|:......::|.||..
Human   261 SFEDAKTQVQ--------LKKIHSSV---ILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVS 314

  Fly   249 HTVNL--DEFRYGGTNITGFRLINEKIVSDVVRQWSIDEKGLLRS--ANLTTVRSETALMYDAVH 309
            ....|  .||..|             ::|.....|....:..:|.  ..|||..|..
Human   315 GNTELIPKEFPSG-------------LISVSYDDWDYSLEARVRDGIGILTTAASSM-------- 358

  Fly   310 LFAKALHDLDTSQQIDIHPISCDGQ----STWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDF 370
                    |:....|.....||.||    ....|  :|..:|..|...|  ..:.|..:|::...
Human   359 --------LEKFSYIPEAKASCYGQMERPEVPMH--TLHPFMVNVTWDG--KDLSFTEEGYQVHP 411

  Fly   371 MLDIVELT-PAGIRKIGTW-NSTL-------PDGINFTRTFSQKQQEIEANLKNKTL-------- 418
            .|.::.|. .....|:|.| |.||       |.    .::||..:.: :.:|...||
Human   412 RLVVIVLNKDREWEKVGKWENHTLSLRHAVWPR----YKSFSDCEPD-DNHLSIVTLEEAPFVIV 471

  Fly   419 -----VVTTILSNPYCMRKESAIPLSGNDQF------EGYAVDLIHEISKSLGFNYKIQLVPDGS 472
                 :..|.:.|....||...|..|.|:..      :|:.:|::.::|:::.|.|.:.||.:|.
Human   472 EDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGK 536

  Fly   473 YGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILY-RKPIKQPPN 536
            :|  .|:...|||||.|::.|||.:|:..|||..||.:.|||:.||:..|:|::. |......|:
Human   537 HG--KKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPS 599

  Fly   537 LFSFLSPLSLDVWIYMATAYLGVS-VLLFILAKFTPYEW---------PAYTDAHGEKVESQFTL 591
              :||.|.|..||:.|....|.|| :.:|:...|:|..:         |     ||    ..||:
Human   600 --AFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAP-----HG----PSFTI 653

  Fly   592 LNCMWFAIGSLMQQGCDFL-PKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAE 655
            ...:|...|.:........ ||..:::::..:|.||.:|.::|||||||||:..|.....:....
Human   654 GKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLS 718

  Fly   656 DLAKQ------TRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVE----R 710
            |...|      ...::|.:..|||....|::    |..|..:|        |..|.:|||    .
Human   719 DKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYM--------TKFNQKGVEDALVS 771

  Fly   711 VAKGKGSYAFLMESTSIEYVTERN--CELTQVGG--MLDTKSYGIATPPNSPYRTAINSVILKLQ 771
            :..||.. ||:.::..:.|...|:  |:|..:|.  :..|..||||....||::..|:..:|:..
Human   772 LKTGKLD-AFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFV 835

  Fly   772 EEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCE--F 834
            .:|::..|:|.|..     |.|..|  |:...:::|.:.|:.|||.:|...|.::.:..:.|  |
Human   836 GDGEMEELETLWLT-----GICHNE--KNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLF 893

  Fly   835 VWKSR 839
            .||.|
Human   894 YWKLR 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..397	CDD:107377	78/393 (20%)
		ANF_receptor	42..378	CDD:279440	66/354 (19%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:304360	116/414 (28%)
		Lig_chan	547..823	CDD:278489	79/300 (26%)
GRIN2A	XP_016878661.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810