Protein Alignment KaiR1D and Grin2c

DIOPT Version :9

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_036707.3
• Gene: Grin2c / 24411
• RGDID: 2739
• Length: 1250
• Species: Rattus norvegicus
• Alignment Length: 898
• Identity: 199/898 - (22%)
• Similarity: 369/898 - (41%)
• Gaps: 162/898 - (18%)

  Fly     1 MRSSGVLVLPLLLLQLILNCRKAQSLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRSK 65
            :.|...|.|||.:..|.:..........:.:|.||...|..| .:.|...||           ::
  Rat    63 LTSQNFLDLPLEIQPLTVGVNNTNPSSILTQICGLLGAARVH-GIVFEDNVD-----------TE 115

  Fly    66 LVAQIERISPFDSFHAGKRVCGLLNI--GVAAIFGPQSSHTASHVQSICDNMEIPHLENRWDYRL 128
            .|||:.      .|.:.:....:|:|  |.|.:..|:...:|.        :::.
  Rat   116 AVAQLL------DFVSSQTHVPILSISGGSAVVLTPKEPGSAF--------LQLG---------- 156

  Fly   129 RRESCLVNLYPHPNTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPF------PI 187
                  |:|......|.|    ::..:.|..|.:|...:.|.....|.::|.....:      .:
  Rat   157 ------VSLEQQLQVLFK----VLEEYDWSAFAVITSLHPGHALFLEGVRAVADASYLSWRLLDV 211

  Fly   188 TVRQLSDSGD---YRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLH 249
            ...:|...|.   .:.||:|:....   :|..||.|....:..:|.|.|::...|.:||.:|.|.
  Rat   212 LTLELGPGGPRARTQRLLRQVDAPV---LVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALG 273

  Fly   250 TVNLD--EFRYGGTNITGFRLINEKIVSDVVRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFA 312
            :.:..  .|..|             ::|.|...|.:.    ||.    .||...|::....|.:.
  Rat   274 STDAPPAAFPVG-------------LISVVTESWRLS----LRQ----KVRDGVAILALGAHSYR 317

  Fly   313 KALHDLDT-SQQIDIH--PISCDGQSTWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDI 374
            :....|.. :.....|  |:|...::.::|   |:|    |..:|  ....|...|:.....:.:
  Rat   318 RQYGTLPAPAGDCRSHPGPVSPAREAFYRH---LLN----VTWEG--RDFSFSPGGYLVRPTMVV 373

  Fly   375 VELTPAGI-RKIGTWNSTLPDGINFTR--TFSQKQQEIEANLKNKTLVVTTILSNPY-------- 428
            :.|....: ..:|.|:    .|:.:.:  .:.:....::..:.::.|.|.|:...|:
  Rat   374 IALNRHRLWEMVGRWD----HGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPDP 434

  Fly   429 ----CM------RKESAIPLSGNDQ-------FEGYAVDLIHEISKSLGFNYKIQLVPDGSYGSL 476
                |:      |::|....|..|.       .:|:.:|::.:::|.:.|:|.:.||.:|.:|
  Rat   435 GTGGCVPNTVPCRRQSNHTFSSGDLTPYTKLCCKGFCIDILKKLAKVVKFSYDLYLVTNGKHG-- 497

  Fly   477 NKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILY-RKPIKQPPNLFSF 540
            .::.|.|||||.|:..:|||:||..|||..||.:.:||:.||:..|:|::. |......|:  :|
  Rat   498 KRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVSRSNGTVSPS--AF 560

  Fly   541 LSPLSLDVWIYMATAYLG-VSVLLFILAKFTPYEWPAYTDAHGEKVESQFTLLNCMWFAIGSLMQ 604
            |.|.|..||:.|....|. |::.:|:...|:|..:........:.....||:...:|.....:..
  Rat   561 LEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKPGGPSFTIGKSVWLLWALVFN 625

  Fly   605 QGCDF-LPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQ------TR 662
            ..... .|:..:::::..:|.||.:|.::|||||||||:..|:....:....|...|      ..
  Rat   626 NSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPP 690

  Fly   663 IKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSI 727
            .::|.:..|||....|.:....:..|..|.:.:.....|:        :..||.. ||:.::..:
  Rat   691 FRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTS--------LKMGKLD-AFIYDAAVL 746

  Fly   728 EYVT--ERNCELTQVGG--MLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKR 788
            .|:.  :..|:|..:|.  :..|..||||...:|.::.||:..:|:|..:|:...|:|.|.
  Rat   747 NYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQLLGDGETQKLETVWL---- 807

  Fly   789 GGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFV--WKSR 839
             .|.|:.|  |:...:::|.:.|:.|||.:|:..||:|.::...|.:  ||.|
  Rat   808 -SGICQNE--KNEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLR 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..397	CDD:107377	71/382 (19%)
		ANF_receptor	42..378	CDD:279440	63/351 (18%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:304360	105/407 (26%)
		Lig_chan	547..823	CDD:278489	68/287 (24%)
Grin2c	NP_036707.3	PBP1_iGluR_NMDA_NR2	41..397	CDD:380601	77/416 (19%)
		PBP2_iGluR_NMDA_Nr2	413..813	CDD:270436	107/417 (26%)
		NMDAR2_C	850..>925	CDD:402274	3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810