Protein Alignment KaiR1D and Grik5

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_006228444.1
• Gene: Grik5 / 24407
• RGDID: 2735
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 867
• Identity: 355/867 - (40%)
• Similarity: 526/867 - (60%)
• Gaps: 60/867 - (6%)

  Fly    12 LLLQLIL-----NCRKAQSLPDIIKIGGLFHPADDH------QELAFRQAVDRINADRSILPRSK 65
            |||.||:     :|:...||    ::..:.   ||.      :.||...|.::||....:..:::
  Rat     5 LLLLLIVAFANPSCQVLSSL----RMAAIL---DDQTVCGRGERLALALAREQINGIIEVPAKAR 62

  Fly    66 LVAQIERISPFDSFHAGKRVCGLLNIGVAAIFGPQSS-HTASHVQSICDNMEIPHLE------NR 123
            :...|..:.....:.....:|.:|..||.::.||.|| .:||.|..||...||||::      .|
  Rat    63 VEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPR 127

  Fly   124 WDYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPFPIT 188
            ..| ||..|  |:|||....:|.|...|::.:.:.:.::|....:.::||:||::...::...::
  Rat   128 LQY-LRFAS--VSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRGFLISKETLS 189

  Fly   189 VRQLSDSGDYRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNL 253
            ||.|.||.|..||||:|::...:.|::|.:....|.||::|.::||.|.::.|::|::|...::|
  Rat   190 VRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLVLRKASELGMTSAFYKYILTTMDFPILHL 254

  Fly   254 DEFRYGGTNITGFRLIN--EKIVSDVVRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFAKALH 316
            |......:||.||.:.|  .....:.||..::..:....::.........|||:||||:...|:.
  Rat   255 DGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYPGPALSAALMFDAVHVVVSAVR 319

  Fly   317 DLDTSQQIDIHPISCDGQSTWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAG 381
            :|:.||:|.:.|::|...:.|.||.||:||:::||..|||..::|:.:|.||::.|.|:|.:..|
  Rat   320 ELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQG 384

  Fly   382 IRKIGTWNSTLPDGINFTRTFSQKQQEIEANLK----NKTLVVTTILSNPYCMRKESAIPLSGND 442
            .|:||.|.|        .||.:.....::.||.    ||||||||||.|||.||:.:...||||:
  Rat   385 HREIGVWYS--------NRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNE 441

  Fly   443 QFEGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTGEWNGMIRELL-EQRADLAIADLTITF 506
            :|||:.||::.|:::.|.|.|:::||.||.||: .:..|.|.||:.||: .|:||||:|..|||.
  Rat   442 RFEGFCVDMLRELAELLRFRYRLRLVEDGLYGA-PEPNGSWTGMVGELINRQKADLAVAAFTITA 505

  Fly   507 EREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTP 571
            |||:.:||:.|||.||:|||||..:.:.|..||||.|.|..||::|..|||.||.:||:.|:.:|
  Rat   506 EREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSP 570

  Fly   572 YEWPAYTD-----AHGEKVESQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMI 631
            |||  |..     |....:|:|:||.|.:||.:|..||||.:.:|:|||||.|:|:||.||||:|
  Rat   571 YEW--YNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIII 633

  Fly   632 SSYTANLAAFLTVERMDSPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESAR 696
            |||||||||||||:||:.|:|||:|||.||.|:||.:..|||..||::|:..||||||::|:|.:
  Rat   634 SSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQ 698

  Fly   697 PSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVGGMLDTKSYGIATPPNSPYRT 761
            ||||..|..||:.||...:  ||||:|||..||....||.|||:||:||||.|||..|..||:|.
  Rat   699 PSVFVKSTEEGIARVLNSR--YAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRD 761

  Fly   762 AINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVA 826
            .|...||:|||..:|.|||.|||:    ||:|..|   ....|..||:.|:||:||||:.|:.:|
  Rat   762 EITLAILQLQENNRLEILKRKWWE----GGRCPKE---EDHRAKGLGMENIGGIFVVLICGLIIA 819

  Fly   827 CVIAVCEFVWKSRKVAVEERLS 848
            ..:||.||:|.:|:.|..|.:|
  Rat   820 VFVAVMEFIWSTRRSAESEEVS 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	113/383 (30%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	204/375 (54%)
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	117/395 (30%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:473866	204/375 (54%)