Protein Alignment KaiR1D and nmr-2

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_001256640.1
• Gene: nmr-2 / 180002
• WormBaseID: WBGene00003775
• Length: 990
• Species: Caenorhabditis elegans
• Alignment Length: 962
• Identity: 216/962 - (22%)
• Similarity: 380/962 - (39%)
• Gaps: 206/962 - (21%)

  Fly    12 LLLQLILNCRKAQSLPDIIKIGG---LFHPADDHQ--------------------ELAFRQAVDR 53
            :||.|.....|.||    |.:||   :..|.:|.:                    :.||::.:.:
 Worm     8 ILLLLATFFEKNQS----IDLGGSRKVQKPKEDPKREDVNIAVVYQHYAGRSKSYDKAFKEVIRK 68

  Fly    54 INADRSILPRSKLVAQ-----IERISPFDSFHAGKRV--CGLLNI---GVAAIFGPQSSHT---- 104
            ||...::....:|..:     ::.|.|..:|.. |.|  |...|:   .||.|....:|.|
 Worm    69 INDATAVSSLRRLATRYNFQAVDCILPTGTFFV-KEVLDCLCNNVTSNNVALIIFVTASETYDST 132

  Fly   105 ----------ASH-----VQSICDNMEIPHLENRWDYRLRRESCLVNLYPHPNTLSKAYVDIVRH 154
                      ||:     :....||.......:...||      ::.:.|.....::|.:.::|.
 Worm   133 TAAEQYFLTAASYTGIPIIAWNADNAGFTFENDLGPYR------IIQMAPPIEHQARAMLALLRR 191

  Fly   155 WGWKTFTII---YENNDGIVRL--QEL-LKAHGMTPFP-ITVRQLSDSGDYRPLLK--QIKNSAE 210
            :.|..|.::   ...||..|..  :|| |.::..|.|. |....::...|....||  .:|.:..
 Worm   192 YNWPKFGVVTSEMAGNDRFVTAIREELELFSNKSTKFEMIHFSHMNTKNDTDVDLKLADVKKNQA 256

  Fly   211 AHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNIT-------GFRL 268
            ..|:|..:..:...:...|:::.|:.:.:.::.|.           ...||..|       |...
 Worm   257 KIILLYANAAQAGTIFSHAEKMDMIGEKYLWIGTQ-----------SVKGTQTTVKAPAQAGMLC 310

  Fly   269 INEKIVSDVVRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHP-ISC- 331
            :|...||:.:.....|...|              ::..|..||..||..|..::...:.. :||
 Worm   311 VNFHTVSNAMFAPRDDILPL--------------IIQLAPKLFGAALLQLRPNEMFSLKSNVSCK 361

  Fly   332 --DGQSTWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDF------MLDIVELTPAGIRKIG-- 386
              ||...|.:|..:..:||...:||....:...|..|...|      ...|::::.......|
 Worm   362 SEDGDPYWDNGKYIYEHMKAAFVKGNPFHVDDGHDSFFYTFEKTGRLRNSILQISNLRTNSKGEK 426

  Fly   387 TWNSTLPDGINFTRTFSQKQQEIE-----AN----LKNKTLV-VTTILSNPY------------C 429
            ||...   || ||.. ..|..:::     ||    ..:|..| |.|:...|:            |
 Worm   427 TWEKV---GI-FTNN-ELKMADVQWPGEKANPPQGAADKFHVKVVTLHEPPFIAVSDVDPDTQKC 486

  Fly   430 MRKESAIPLSGNDQF----------------EGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNK 478
            ...:.:|...|:.::                .||.|||:::::..:||.|.:..|.|..:|.  |
 Worm   487 PGNQGSICDWGDVEYTDGAGVKKNRTLLKCCSGYCVDLLNKLANDIGFTYTLYKVRDEKWGL--K 549

  Fly   479 LTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSIL--YRKPIKQPPNLFSFL 541
            ....|||:|.:|:..:||:.:..|.:..||.:.:||:.||::.|:||:  .|..:..|.   :||
 Worm   550 TENGWNGLIADLMHNKADMCVTSLKLNSERARDIDFSLPFLDTGISIIVKIRSGVLSPT---AFL 611

  Fly   542 SPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKV---ESQFTLLNCMWFAIGSLM 603
            .|.....|:.:....:.|:.:...|     :||.:....:.:|.   |.:|:|....|....:|.
 Worm   612 EPFEYSTWVIILFVCIHVAAISIFL-----FEWVSPYSFNMQKYPPPEHKFSLFRSYWLVWATLF 671

  Fly   604 QQGCDF-LPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERM---------DSPIESAEDLA 658
            ...... :||:..:|::|.:|..|.|..::.||||||||: :.|:         |..:....|
 Worm   672 SASVSTDVPKSTVSRLMALVWAAFGLTFLAVYTANLAAFM-ITRVQYYDLSGIHDPMLNFPHD-- 733

  Fly   659 KQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMES--ARPSVFTASNGEGVERVAKGKGSYAFL 721
            ::...::|.:.||:|.        .|.:|.|..|..  .....|..:...|:|.| |.:...||:
 Worm   734 QKPPFRFGTVDGGNTH--------ETMKRNWHKMHEYVKHNKYFRMNISAGIEAV-KNEELDAFI 789

  Fly   722 MESTSIEYVT--ERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWW 784
            .::..::|..  :.||.|..||.......|||..|.|||:.:.:|..:|:.|::|.|..|:..|.
 Worm   790 YDAVVLDYWAGKDANCALMTVGKWASMTGYGIGFPKNSPHTSLVNHYMLQYQQKGDLERLQNFWL 854

  Fly   785 KEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVW 836
            .     |.|..: |.|.:.:..||:.|....||:|.||:.|:.::...|.::
 Worm   855 T-----GACTPD-SHSQTQSAPLGIENFLSAFVLLAGGIIVSVIVLGFEHIY 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	85/448 (19%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	106/417 (25%)
nmr-2	NP_001256640.1	Periplasmic_Binding_Protein_type1	102..443	CDD:471960	75/376 (20%)
		Periplasmic_Binding_Protein_Type_2	460..860	CDD:473866	108/426 (25%)