Protein Alignment KaiR1D and nmr-1

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_495033.2
• Gene: nmr-1 / 173929
• WormBaseID: WBGene00003774
• Length: 1025
• Species: Caenorhabditis elegans
• Alignment Length: 896
• Identity: 215/896 - (23%)
• Similarity: 355/896 - (39%)
• Gaps: 192/896 - (21%)

  Fly    89 LNIGVAA----IFGPQSSHTASHVQSIC-------DNMEIPHLENRWDY---RLRRESCLVNLYP 139
            |.:.|.|    :||..|.|..:...|..       ||    .||...|.   ::...|....::.
 Worm    39 LKVSVTAAFVEVFGSTSYHLGNDTISAAFVDAKSGDN----RLELTQDIVCSQMLNHSLASVIFS 99

  Fly   140 HPNTLSKAYVDIVRHWGWKTFTIIYENNDGI---VRLQELLKAHGMTPFPITVRQLSDSGDYRPL 201
            ...|.|..::|:|..   ..:|:.:.....:   ||..|..|.:   .:|..||..:      ||
 Worm   100 PLLTSSSRFIDLVTS---SAYTLSFYKLPVVGVMVRDAEFSKKN---IYPTFVRPTA------PL 152

  Fly   202 LKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEF---------- 256
                  |.||.:.|       |.:|.        ..|...:|.|:. ..:|.|:|
 Worm   153 ------SDEAFVFL-------HMLLS--------LKYRQVVVLSVK-RDINADQFVEEFEKRRVE 195

  Fly   257 ------RY---------GGTNITGFRLINEKIV------SDVVR-------------QWSIDEKG 287
                  ||         ..|....|..:...|:      .|.||             .|.:.|..
 Worm   196 FKIIVQRYIEVELNENLNDTLAESFEEVTSNIIVLFAKKDDAVRIFANAGDLTGKGKVWIVSESA 260

  Fly   288 ----LLRSANLTTVRSETA--LMYDAVHLFAKALHDLDTSQQIDIH-PISCDGQST---WQ--HG 340
                .:.:.:|.....:||  ::.|:..:...|:..:....:|||. |:.||..|.   |.  ..
 Worm   261 GEAHNVPNGSLGCRLGQTAFSVLRDSFSILKSAMETIFRESKIDIFPPVECDRDSVDAEWNSLQA 325

  Fly   341 FSLINYMKIVEMKGL-TNVIKFDHQGFRTDFMLDIV----ELTPAGIRKIGTWNSTLPDGINFTR 400
            .:|:|     |:.|. |:.:.|:.:..|.....||:    |....| ..:|.......|.|.:..
 Worm   326 PALLN-----EICGTSTSRVHFNDKCERIGVEYDIINFHMERKQVG-NMVGDILRLDEDSIEWAG 384

  Fly   401 TFSQKQQEIEANLKNKTL-----VVTTILSNP-YCMRKESAI------------------PLSGN 441
            .....:..:..:|:..|:     |.||.:.:| .|....:.:                  ||:..
 Worm   385 GTKPLEISLPKHLRVVTVADPPFVYTTPIGSPSQCAELGNTVVEWSIFDKIVVSGPWYSCPLTLE 449

  Fly   442 DQFE-----GYAVDLIHEIS-----KSLGFNYKIQLVPDGSYG--SLNKLTG-EWNGMIRELLEQ 493
            :..|     |.|:||:..:|     .|:..::...|..:.|||  ..::.|| ..:|:|.||...
 Worm   450 NSTEYFCCAGLAIDLLSNLSLPEANNSIDTSFTFSLHLNESYGVVQASETTGITISGVIGELDGD 514

  Fly   494 RADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLG 558
            .||:||..:||..|||:.||||.|::..|:.|| .|.|.:...:.|||.||...:|..:..:.:.
 Worm   515 TADMAIGGITINPERERIVDFTEPWLYHGIRIL-EKNIPRDSPMQSFLQPLQSSLWTALFISVIL 578

  Fly   559 VSVLLFILAKFTPYEWPAYTDAHGEK-VESQFTLL------------NCMWFAIGSLMQQG-CDF 609
            |.:.::.|...:|:|.....|...|: ::.:|.|.            ..|||..|.|:..| .:.
 Worm   579 VGLAIYCLDFKSPFERFYQADKEMEQDLKKEFELWIGKDADENVNFGEAMWFVWGVLLNSGVSEK 643

  Fly   610 LPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAED---LAKQTRIKYGALKGG 671
            .|::.|.|::..:|..|.:||::||||||||||.:::.:..:....|   ........:|.:...
 Worm   644 TPRSCSARVLGIVWCGFCMIMVASYTANLAAFLVLDQPEKGLTGVTDPRLRNPSANFSFGTVLNS 708

  Fly   672 STAAFFRDSKISTYQRMWSFMESARP-SVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNC 735
            :...:|:     .:..:.|......| :|..||  |.|..:..|... ||:.:||.:|:...|:|
 Worm   709 NVYQYFK-----RHVELSSMFRKMEPHNVRRAS--EAVHSLLNGSLD-AFIWDSTRLEFEAARHC 765

  Fly   736 ELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKS 800
            ||...|.:....:|||....|||:...|.|.||::.|.|.:..|..||  ..|||..|.||..||
 Worm   766 ELRTRGSLFGRSAYGIGLQKNSPWTPHITSAILRMSESGVMEKLDQKW--IDRGGPNCVVEAHKS 828

  Fly   801 SSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKVAVEERLSAIL 851
            .:   .|||.|:..:|:::..|:.:...::..| |...|::|.:.|...|:
 Worm   829 PA---RLGLVNMKDIFILVSSGVALGIFLSFVE-VSYGRRLADKGRRRRIV 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	77/388 (20%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	117/424 (28%)
nmr-1	NP_495033.2	Periplasmic_Binding_Protein_type1	19..384	CDD:471960	77/388 (20%)
		PBP2_iGluR_NMDA_Nr1	394..822	CDD:270437	121/438 (28%)
		Lig_chan	566..844	CDD:459656	81/290 (28%)
		LITAF	949..1017	CDD:197841