Protein Alignment KaiR1D and Grid1

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_032192.2
• Gene: Grid1 / 14803
• MGIID: 95812
• Length: 1009
• Species: Mus musculus
• Alignment Length: 919
• Identity: 275/919 - (29%)
• Similarity: 446/919 - (48%)
• Gaps: 110/919 - (11%)

  Fly     9 LPLLLLQLILNCRKAQSLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRSKLVAQIERI 73
            |.|.||..|..|...:: ..||.||.:|.......:..|:.||..::.:..||...|:...|:.|
Mouse     4 LTLWLLPWICQCVTVRA-DSIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVI 67

  Fly    74 SPFDSFHAGKRVCGLLNIGVAAIFGPQSSHTASHVQSICDNMEIPHL-ENRWDYRLRRESCLVNL 137
            ...:.|.|.:..|.|:..|:.|:.......:|:.:||:.|.|.|||| ..|......|.:|.:|.
Mouse    68 EANNPFQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNP 132

  Fly   138 YPH----------PNTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLK-------------- 178
            .|.          |..|:...:.:|....|:.|.:.|::...|..||..|.
Mouse   133 SPDGEAYTLASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKV 197

  Fly   179 ----AHGMTPFPITVRQLSDSGDYRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMS-DY 238
                :|..|.. .|..:..:...||..|::        .:|..|.:..|..:.:|.:..:.| |.
Mouse   198 DKNISHVFTSL-FTTMKTEELNRYRDTLRR--------AILLLSPQGAHSFINEAVETNLASKDS 253

  Fly   239 HSYLVTS--LDLHTVNLDEFRYGGTNITGFRLI------NEKIVSDVVRQWSI---DEKGLLRSA 292
            |...|..  .|...::|.....|  .:|..|.|      |:|.:.:..|..|:   .::|.|:..
Mouse   254 HWVFVNEEISDPEILDLVHSALG--RMTVVRQIFPSAKDNQKCMRNNHRISSLLCDPQEGYLQML 316

  Fly   293 NLTTVRSETALMYDAVHLFAKALH-DLDTSQQIDIHPISCDGQST--WQHGFSLINYMKIVEMKG 354
            .::.:     .:||:|.:.|.|.| .|:..:...:..::|..:||  |..|.|:::.:|...:.|
Mouse   317 QISNL-----YLYDSVLMLANAFHRKLEDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGHITG 376

  Fly   355 LTNVIKFDHQGFRTDFMLDIVELTPA-----GIRKIGTWNSTLPDGINFTRTFSQKQQEIEANLK 414
            ||.|::|...........:|:..|.:     .:||:.||:|  ..|:|    .|.:::.:.:.|:
Mouse   377 LTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDS--EKGLN----GSLQERPMGSRLQ 435

  Fly   415 NKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKL 479
            ..||.|.|:|..|:.|..|:.  |....:::|:::|::..::|:|||.|:|...|||.||.....
Mouse   436 GLTLKVVTVLEEPFVMVAENI--LGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHN 498

  Fly   480 TGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPL 544
            | .|||||.||:.:||||||:.:|||.|||..|||:..:|:..|.||.:|| ::..::||..:|.
Mouse   499 T-SWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYSVGILIKKP-EEKISIFSLFAPF 561

  Fly   545 SLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGCDF 609
            ...||..:|.|...|.||:|:|.:.......:.|.   .:..:..||.:.:|...|:.:|||.:.
Mouse   562 DFAVWACIAAAIPVVGVLIFVLNRIQAVRSQSATQ---PRPSASATLHSAIWIVYGAFVQQGGES 623

  Fly   610 LPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTRIKYGALKGGSTA 674
            ...:::.|:|.|.||.||||:.|||||||||||||.|||:||.:.:||:||..:.||.::..:..
Mouse   624 SVNSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLSKQLEMSYGTVRDSAVY 688

  Fly   675 AFFRD------SKISTYQRMWSFMESARPSVFTASN-GEGVERVAKGKGSYAFLMESTSIEY--V 730
            .:||.      .:.||:..:|..:.....:....|| .||: |.|| ||:||||.:...:||  :
Mouse   689 EYFRAKGTNPLEQDSTFAELWRTISKNGGADNCVSNPSEGI-RKAK-KGNYAFLWDVAVVEYAAL 751

  Fly   731 TERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRV 795
            |:.:|.:|.:|..:.:|.||||....||||...:..||:||:.|.|.:||.|||...   |:|.:
Mouse   752 TDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHT---GRCDL 813

  Fly   796 ETSKSS--SAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKV--------------AVE 844
             ||.||  :....|.|.:..|||.:|..|:.:||::|..|..|.|.:.              .|.
Mouse   814 -TSHSSTQTEGKSLKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCHQETPKEDKEVNLEQVH 877

  Fly   845 ERLSAILNE 853
            .|::::::|
Mouse   878 RRINSLMDE 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	95/417 (23%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	147/378 (39%)
Grid1	NP_032192.2	Interaction with CBLN1. /evidence=ECO:0000269|PubMed:27418511	21..436		99/436 (23%)
		PBP1_iGluR_delta_1	25..425	CDD:380615	95/421 (23%)
		PBP2_iGluR_delta_1	436..806	CDD:270448	147/378 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..960