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Protein Alignment KaiR1D and Gria1

DIOPT Version :9

Sequence 1:	NP_650925.1	Gene:	KaiR1D / 42473	FlyBaseID:	FBgn0038837	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus

Alignment Length:	846	Identity:	335/846 - (39%)
Similarity:	512/846 - (60%)	Gaps:	63/846 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 SLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRSKLVAQIERISPFDSFHAGKRVCGLL 89
            :.|:.|:|||||......:..|||.|:.::.....:||      ||:.::..|||....|.|...
Mouse    20 NFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLP------QIDIVNISDSFEMTYRFCSQF 78

  Fly    90 NIGVAAIFGPQSSHTASHVQSICDNMEIPHL--------ENRWDYRLRRESCLVNLYPHPNTLSK 146
            :.||.||||.....|.:.:.|.|..:.:..:        .|::..:||.|            |.:
Mouse    79 SKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPE------------LQE 131

  Fly   147 AYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPFPIT---VRQLSDSGDYRPLLKQIKNS 208
            |.:.|:.|:.|:||..||:.:.|:..||.:|.......:.:|   :...::.| ||.|.:.::..
Mouse   132 ALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEG-YRMLFQDLEKK 195

  Fly   209 AEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLIN--E 271
            .|..:|:||.:||::.:|.|..::......:.|::.:|....::|::|:..|.|:|||:|:|  :
Mouse   196 KERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTD 260

  Fly   272 KIVSDVVRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPISCDGQS- 335
            .|.:.:::||...:.......:....:..:||.||.|.:.|:|...| ..|:|||......|..
Mouse   261 TIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSL-RRQRIDISRRGNAGDCL 324

  Fly   336 -----TWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAGIRKIGTWNSTLPDG 395
                 .|..|..:...::.|..:|||..::|:.:|.||::.|.::|:...||||||.||.  .|.
Mouse   325 ANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNE--DDK 387

  Fly   396 INFTRTFSQKQQEIEANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLG 460
            .....|.:|...: .::::|:|.:|||||.:||.|.|::|....|||::|||.|:|..||:|.:|
Mouse   388 FVPAATDAQAGGD-NSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVG 451

  Fly   461 FNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSI 525
            ::|::::|.||.||:.:..|..||||:.||:..|||:|:|.||||..||:.:||:.|||:||:||
Mouse   452 YSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISI 516

  Fly   526 LYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVE---- 586
            :.:||.|..|.:||||.||:.::|:.:..||:||||:||::::|:||||      |.|:.|
Mouse   517 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW------HSEEFEEGRD 575

  Fly   587 -------SQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTV 644
                   ::|.:.|.:||::|:.||||||..|::||.|:|.|:|||||||:||||||||||||||
Mouse   576 QTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 640

  Fly   645 ERMDSPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVE 709
            |||.|||||||||||||.|.||.|:.|||..|||.|||:.:::||::|:||.||||..:..||:.
Mouse   641 ERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMI 705

  Fly   710 RVAKGKGSYAFLMESTSIEYVTERN-CELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEE 773
            ||.|.||.||:|:|||..||:.:|. |:..:|||.||:|.||||||..|..|..:|..:|||.|:
Mouse   706 RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQ 770

  Fly   774 GKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKS 838
            |.|..||:|||.:|   |:|..:.|.|....:.|.|:||.|||.:|:||:|:|.::|:.||.:||
Mouse   771 GVLDKLKSKWWYDK---GECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKS 832

  Fly   839 R 839
            |
Mouse   833 R 833

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.