Protein Alignment KaiR1D and Nmdar2

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_061504088.1
• Gene: Nmdar2 / 1275196
• VectorBaseID: AGAMI1_003064
• Length: 910
• Species: Anopheles gambiae
• Alignment Length: 846
• Identity: 194/846 - (22%)
• Similarity: 349/846 - (41%)
• Gaps: 175/846 - (20%)

  Fly   100 QSSHTASHVQSICDNMEIPHLENRW-------DYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGW 157
            :|:.:|.:...:...:.||.:.  |       :.|..:.:..:.|.|.....|.|.:.|:..:.|
Mosquito     9 RSTASAQYFLQLAGYLGIPVIS--WNADNSGLERRASQSALQLQLAPSIEHQSAAMLSILERYKW 71

  Fly   158 KTFTIIYE----NNDGIVRLQELLKAHGMTPFPITVRQLSDSGDYRPL-LKQIKNSAEAHIVLDC 217
            ..|:::..    ::|.:..::|.:.|  |..|..|:  |:.....||. |.::.||....::|.|
Mosquito    72 HQFSVVTSQIAGHDDFVQAVREQVGA--MDHFKFTI--LNSIIVTRPSDLLELVNSEARVMLLYC 132

  Fly   218 STERIHEVLKQAQQIGMMSDYHSYLVT-SLDLHTVNLDEFRYGGTNI----TGFRLINEKIVSDV 277
            :.....|:|..|:::.:..:.:.::|| |:..:|....:|..|...:    :...|:||  ::..
Mosquito   133 TKSEAIEILHAAEELQITGENYVWVVTQSVIENTQTHPQFPIGMLGVHFDTSSGALVNE--IATA 195

  Fly   278 VRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPISCD--GQSTWQHG 340
            :|.::...:..|....                         :|.:::|.|.:||:  |:..|..|
Mosquito   196 IRVYAYGVEYYLNDVK-------------------------NTGRRLDTHQLSCEDQGRGRWDSG 235

  Fly   341 FSLINYMKIVEMKGLTNV--IKFDHQGFRTDFMLDIVELTPA----GI--RKIGTWNS------- 390
            .....|::.|.::..:|.  |:|...|......|.|:.|.|:    |:  .:||.|.|
Mosquito   236 EVFFKYLRNVSLESESNKPNIEFTADGDLKSAELKIMNLRPSVNSKGLVWEEIGIWKSWQQQKLD 300

  Fly   391 -----------TLPDGINFTRTFSQKQQEIEANLKNKTLVVTTILSNPYCMRKESAIPLSG---- 440
                       |.|.|:  ...|..|              :|.:...|| :....|.|:||
Mosquito   301 IRDIAWPGNSHTPPQGV--PEKFHLK--------------ITFLEEAPY-INLSPADPVSGKCLM 348

  Fly   441 ------------------------NDQF----EGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLN 477
                                    |..|    .|:.:||:.:.::.|||.|::..|.||.:|:|.
Mosquito   349 DRGVLCRVAADHEMTDIDMGQAHKNGSFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLE 413

  Fly   478 KLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILY--RKPIKQPPNLFSF 540
              .|:|||:|.||:.::.|:.:..|.|..|||..|||:.|||..|::|:.  |..|..|.   :|
Mosquito   414 --NGKWNGLIHELVNRKTDMVLTSLMINAEREAVVDFSEPFMETGIAIVVAKRTGIISPT---AF 473

  Fly   541 LSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEW--PAYTD-----AHGEKVESQFTLLNCMWFA 598
            |.|.....|:.:....:..:..:..|     :||  |:..|     .:|:....:|:|....|..
Mosquito   474 LEPFDTASWMLVGIFAIQAATFMIFL-----FEWLSPSGYDMKTVLQNGQTTPYRFSLFRTYWLV 533

  Fly   599 IGSLMQQGCDF-LPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAED------ 656
            ...|.|..... .|:..::|.:..:|..|.::.::.||||||||:............:|
Mosquito   534 WAVLFQAAVHVDSPRGFTSRFMTNVWAMFAVVFLAIYTANLAAFMITREEFHEFTGLDDSRLSHP 598

  Fly   657 LAKQTRIKYGALKGGSTAAFFRDSKISTY-QRMWSFMESARPSVFTASNGEGVERVAKGKGSYAF 720
            .:.:..||:|.:....|     ||.||.| :.|..:|:....|    |..:||..|..|:.. ||
Mosquito   599 FSHKPTIKFGTIPWSHT-----DSTISKYFKEMHYYMKQYNRS----SVADGVTAVLSGQLD-AF 653

  Fly   721 LMESTSIEYVTER--NCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKW 783
            :.:.|.::|:.::  :|.|..||.......||:|...||.|....|..:|:.:..|.|..|:..|
Mosquito   654 IYDGTVLDYLVQQDEDCRLLTVGQWYAMTGYGLAFSRNSKYVGMFNKRLLEFRANGDLERLRRFW 718

  Fly   784 WKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCE---FVWKSRKVAVEE 845
            ..     |.||....:..| ::.|.|......|::||.|:.:|.::.:.|   |.:..:::|.::
Mosquito   719 MT-----GTCRPGKQEHKS-SDPLALEQFLSAFLLLMAGILLAALLLLLEHLYFKYFRKRLAKKD 777

  Fly   846 R 846
            |
Mosquito   778 R 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	67/344 (19%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	110/420 (26%)
Nmdar2	XP_061504088.1	None