Protein Alignment KaiR1D and Ir93a

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_061512014.1
• Gene: Ir93a / 1272000
• VectorBaseID: AGAMI1_007780
• Length: 876
• Species: Anopheles gambiae
• Alignment Length: 970
• Identity: 208/970 - (21%)
• Similarity: 359/970 - (37%)
• Gaps: 238/970 - (24%)

  Fly     1 MRSSGVLVLPLLLLQLILNCRKAQSLPDIIKIGGLFHPA--DDHQELAFRQAVDRINADRSILPR 63
            :|..|:..:.||||.|:|.       ||         ||  ||...|....|...|     ||.|
Mosquito     3 LRLVGLWSILLLLLLLVLR-------PD---------PAVGDDFPSLLSTNASMAI-----ILDR 46

  Fly    64 SKLVAQIERISPFDSFHAGKRVC------GLLNIGVAAIFGPQSSHTASHVQSICDNMEIPHLEN 122
            ..|.|..||     :....|.|.      .|.|.|:...:...:|.......|..  :.:...:|
Mosquito    47 EYLGADYER-----TLDETKNVVEKLIREHLKNGGLIVKYYSWTSINLKRDFSAV--LSVSSCKN 104

  Fly   123 RWD-YRLRRESCLVNL---------YPHPNTL---------SKAYVDI---------VRHWGWKT 159
            .|| |:......||.|         .|..|.:         |.|:.::         .|...|.|
Mosquito   105 TWDIYQEAVRERLVMLSITDPDCPRLPTNNAIMIPRSDGSGSNAFDEVSQIILDMKSSRAINWHT 169

  Fly   160 FTIIYENNDGIVRLQELLKAHGMTPFPITVRQLSDSGDYRPL-LKQIKNSAEAHIVLDCSTERIH 223
            .|::|:.    |...|:.:.        .:..|.|....:|| |.:.|.:|..|     |.|:..
Mosquito   170 ATLLYDQ----VYDAEISRC--------ILSLLEDREGIKPLTLTEFKINAPTH-----SWEKRK 217

  Fly   224 EVLKQAQQIGMMSDYHS--------------YLVTSLDLHTVN-LDEFRYGGTNITGFRLINEKI 273
            |:.:..  :|:.:.|..              .:..|.||..|| ..::.|...|       .||.
Mosquito   218 EIRRTL--LGIPTAYTGRNFIAIVNIATLTLLMEISKDLKLVNPFAQWLYLIPN-------TEKA 273

  Fly   274 VSDVVRQWSIDEKG-----LLRSANLTTVRSETALMYDAVHL--FAKALHDLDTSQQIDIHPIS- 330
            .|:...|.::..:|     :..|.:.....:.:.|.|...:|  |.::|..|...:|:....||
Mosquito   274 NSNFTTQSTLINEGDNVAFVYNSGSKAQNCTVSVLCYIESYLLHFIRSLSKLIREEQVVFGQISD 338

  Fly   331 ------------------------------CDGQSTWQHGFSLINYMKIVEMKGLTNVIKFDHQG 365
                                          |:..|.|:        ::..|..|..
Mosquito   339 EEWEIIRPSKQERKTKFLQMIKAAITSKDECNKCSQWK--------IQSAETWGYV--------- 386

  Fly   366 FRTDFMLDIVELTPAGIRK-----IGTWNSTLPDGINFTRTFSQKQQEIEANLKNKTLVVTTILS 425
            :||||:.|..:|...  ||     ||.|:.  .||...|.......|   ...:...|:..:..:
Mosquito   387 YRTDFLTDGADLQER--RKYTMLDIGYWSP--QDGFMLTDALFPHTQ---YGFRGVQLIFYSYHN 444

  Fly   426 NP--YCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQL---------VPDGSYGSLNKL 479
            .|  :....:|..|:..:    |...|:::|:|:.|.|.|.:.:         :.:|:..|:..|
Mosquito   445 PPWQFVAYNDSGSPVISS----GVVYDILNELSRKLNFTYTMVISQPAEINGSLVEGNTSSVYDL 505

  Fly   480 TGEWNGMIRE----LLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSF 540
            ....:.:.:|    |:..:..||....|:..::::.|.||.|......|.:..:| ::...:..|
Mosquito   506 KTISSDIPQEIFSTLVNNKILLAAVGATVNEKQKKFVSFTDPISIQTYSFVISRP-RELSRVLLF 569

  Fly   541 LSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVESQF-TLLNCMWFAIGSLMQ 604
            |||...|.|:.:|.|...:..:|..:.|.:|     |.:.|.:..::.. .:.||.|:..|:|:|
Mosquito   570 LSPFGSDTWLCLAAAVALMGPILCAINKLSP-----YYEVHNKPTDTGLGKVNNCFWYIYGALLQ 629

  Fly   605 QGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTR-IKYGAL 668
            ||..:||.|.|.|::.|.||...|:::::|..||.||||..::|.|:.....|.:..| :.:...
Mosquito   630 QGGLYLPYADSGRIIIGTWWLVVLVIVTTYCGNLVAFLTFPKIDIPVNRVMQLLRNDRGMTWSIR 694

  Fly   669 KGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKG-------KGSYAFLMESTS 726
            :|........||....|.:::...:     :......|.|||:..|       :.:..:||:.
Mosquito   695 RGTFLEEMLMDSTEPKYMQLYKGSQ-----IIGELTDELVERIEAGQHVHIDWRNNLRYLMKR-- 752

  Fly   727 IEYVTERNCELT-QVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKW------W 784
             :::....|:.. .....|| :...:..|.:|||...:|..|.::.:.|.:.    :|      .
Mosquito   753 -QFLRTDRCDFALSTDEFLD-EQIALVMPKDSPYLELVNEEIKRMHQFGFIQ----RWVAQYLPA 811

  Fly   785 KEKRGGGKCRVETSKSSSAANE-LGLANVGGVFVVLMGGMGVACVIAVCEF--VW--KSR 839
            |:|..|      |.:.....|. :..:::.|.:.:|:.|......:.||||  .|  |||
Mosquito   812 KDKCSG------TGRVMDVQNHTVNSSDMAGSYWILLLGFVSGLFVFVCEFAVAWYRKSR 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	92/463 (20%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	88/400 (22%)
Ir93a	XP_061512014.1	None