Protein Alignment KaiR1D and grik3

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_017206939.1
• Gene: grik3 / 100334689
• ZFINID: ZDB-GENE-211021-1
• Length: 991
• Species: Danio rerio
• Alignment Length: 850
• Identity: 397/850 - (46%)
• Similarity: 573/850 - (67%)
• Gaps: 54/850 - (6%)

  Fly    26 LPDIIKIGGLFHPAD------DHQELAFRQAVDRINADRSILPRSKLVAQIERISPFDSFHAGKR 84
            :|.:|:|||:|...|      ..:||||:.||:.||.:|::||.:.|...|:||:.:|||.|.::
Zfish    27 MPHVIRIGGIFEQTDGPVALVSSEELAFKFAVNNINRNRTLLPNTTLTYDIQRINIYDSFEASRK 91

  Fly    85 VCGLLNIGVAAIFGPQSSHTASHVQSICDNMEIPHLENRWDYRL--RRESCLVNLYPHPNTLSKA 147
            .|..|::||.|||||..|.:::.|||||:.:|:||::.||.:..  .|::...||||..::||.|
Zfish    92 ACDQLSLGVVAIFGPSHSSSSNAVQSICNALEVPHIQVRWKHHPMDNRDTFYANLYPDYSSLSYA 156

  Fly   148 YVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPFPITVRQL-SDSGDYRPLLKQIKNSAEA 211
            .:|:|:...|||.|::|:::.|::|||||:.|.......:.:||| .|:.|.|||||::|.|.|.
Zfish   157 ILDLVQFLKWKTATVVYDDSTGLIRLQELIMAPSRYNIRLKIRQLPMDTVDTRPLLKEMKRSREF 221

  Fly   212 HIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLIN--EKIV 274
            .|:.|||.....::|||||.:|||::|:.|:.|:|||..:||:.:|:.|.|:||||::|  ...|
Zfish   222 RIIFDCSHTMAAQILKQAQMMGMMTEYYHYIFTTLDLMAINLEPYRFCGVNMTGFRILNVDNPQV 286

  Fly   275 SDVVRQWSID-------EKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPISCD 332
            :.:|.:||::       :.|||... :||   :.||.|||||:.:.:...   :.|:.::.:.|.
Zfish   287 ASIVEKWSLERQIPPKPDSGLLEGI-MTT---DAALTYDAVHIVSVSYQH---APQMTVNSLQCH 344

  Fly   333 GQSTWQHGFSLINYMKIVEMKGLTNVIKFDH-QGFRTDFMLDIVELTPAGIRKIGTWNSTLPDGI 396
            ....|:.|...::::|.....|||..:.|:. .|.||||.||||.|...|::|:|.|:::  .|:
Zfish   345 RHKPWRFGGRFMSFIKESHWDGLTGRLCFNRTTGLRTDFDLDIVSLKEDGLQKVGKWSAS--GGL 407

  Fly   397 NFTRTFSQKQQEIEANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGF 461
            |.|....|....|..:|.|::||:||||..||.|.|:|...|.|||:|||:.:||:.|::..|||
Zfish   408 NITEVPRQNGMNITDSLSNRSLVITTILEEPYVMLKKSDKALVGNDRFEGFCIDLLKELASILGF 472

  Fly   462 NYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSIL 526
            :|:|.|||||.||..:. .|:||||||||:|.|||||:|.|||||.||:|:||:.||:|.|:|||
Zfish   473 SYEIHLVPDGKYGFQDD-KGQWNGMIRELMEHRADLAVAPLTITFMREKAIDFSKPFLNTGISIL 536

  Fly   527 YRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAH-----GEKVE 586
            ||||.......||||:|::.|:|:|:..||||||.:||::|:|:||||   .|||     .:.||
Zfish   537 YRKPNSTNSGFFSFLNPMTPDIWVYILLAYLGVSCVLFVIARFSPYEW---YDAHPCNPGSDVVE 598

  Fly   587 SQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPI 651
            :.|||||..||.:|||||||.:.:|||||||::.|||||||||:||||||||||||||||||||:
Zfish   599 NNFTLLNSFWFGVGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMDSPV 663

  Fly   652 ESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKG 716
            :||:||||||:|:||.:|.|:|.:||:.|::||:::||:||.|.:.:.|..|..:|::||.  |.
Zfish   664 DSADDLAKQTKIEYGVVKDGATMSFFKKSRVSTFEKMWAFMSSRQSTSFVKSIEDGIQRVL--KS 726

  Fly   717 SYAFLMESTSIEYVTERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKT 781
            .||.|||||:|||||.|||.||||||::|:|.|||.||..||||..|...||.:.|:|:||:||.
Zfish   727 DYALLMESTTIEYVTRRNCNLTQVGGIIDSKGYGIGTPKGSPYRDKITIAILGILEDGRLHMLKE 791

  Fly   782 KWWKEKRGGGKC----RVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKVA 842
            |||    .|..|    |.||       ..:|:.|:||:|:||..|:.::..:|:.||::|.||.|
Zfish   792 KWW----SGSSCLEDERYET-------GPMGIQNLGGIFIVLASGLVLSVFVAIGEFIYKLRKTA 845

  Fly   843 VEERL 847
            ..|::
Zfish   846 EREQV 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	148/387 (38%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	221/374 (59%)
grik3	XP_017206939.1	PBP1_iGluR_Kainate	32..410	CDD:380605	148/386 (38%)
		Periplasmic_Binding_Protein_Type_2	426..794	CDD:473866	220/373 (59%)