Protein Alignment KaiR1D and grin3bb

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_017213803.2
• Gene: grin3bb / 100333101
• ZFINID: ZDB-GENE-131122-77
• Length: 1114
• Species: Danio rerio
• Alignment Length: 938
• Identity: 211/938 - (22%)
• Similarity: 364/938 - (38%)
• Gaps: 194/938 - (20%)

  Fly    11 LLLLQLILNCRKAQSLPD----------IIKIGGLFHPADDHQELAFRQAVDR-----INADRSI 60
            :.||..:|..:.|.|.|.          .:::|.|..|   .|.:..|.|:.|     ..:..:.
Zfish    18 IFLLHTLLLLQPAHSHPQPCHILARIGHTVRLGALLPP---RQSVRVRAALHRALSGLAESGNNF 79

  Fly    61 LPRSKLVAQIERIS----PFDSFHAGKRVC-GLLNIGVAAIFG-PQSSHTASHVQSICDNMEIPH 119
            ||.:..:..:.|.:    |...|..   || .::..||:|:.. ||:......::.:...:|||.
Zfish    80 LPYNLSLDVVAREAQSGDPESLFRC---VCQDIVVQGVSAVLAFPQTQEEIVQMEFMSSFLEIPF 141

  Fly   120 L-----------ENRWDYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGW-KTFTIIYE--NNDGI 170
            :           :||:..:      :....| |:.|.:..:.:::..|| ::..::..  .:.|:
Zfish   142 ISIIEHGEPLKTQNRFHLQ------MTTRIP-PSGLVELLLAVLQRSGWEESMAVLCHGWEDAGL 199

  Fly   171 VRLQELLKAHGMTPFPITVRQLSDSGDYRPLLKQIKNSAEAHIVLDCS-----------TERIHE 224
            :.|.:|....|..|....:|...:.......:..|.:....|..||.|           .|....
Zfish   200 LDLLKLQGRFGWGPSQWHLRAALNLSHSTARMANISDFLSEHFNLDHSPPASVLLFGADPECASS 264

  Fly   225 VLKQAQQIGM-MSDYHSYLVTSLD---LHTVN--LDEFRYGGTN--------ITGFRLINEKIVS 275
            ||:.|..:|: :...|..:...|.   ||::.  |....||..:        ....:|||..:.:
Zfish   265 VLRSAHDLGLTLPTVHWIMGHPLSPDALHSIGLPLGLLAYGEVDHKPLDFYISDALQLINRAVTA 329

  Fly   276 DVVRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFAKA-LHDLDTSQQI------DIHPISCDG 333
                              .|.||.:.||:.:.|:.|.|. .|:|.:|.|.      :...:...|
Zfish   330 ------------------ATVVRPDLALIQNMVNCFDKPNKHELPSSGQYIARFLSNTSFVGLTG 376

  Fly   334 QSTWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAGIRKIGTWNSTLPDGINF 398
            ....|...|.::....|.:..|    :.|..|..|...:...|.....:.:.|.|..:.|.
Zfish   377 PVIVQRNLSRVHTSHKVHIWSL----RRDAVGQPTWVTVGSWEGGRLNVEEQGLWQGSSPR---- 433

  Fly   399 TRTFSQKQQE-----IEANLKNKTLVVTTILSNPYCMRKE------------------------- 433
            .||..|..:|     ....:....|.|.|::.:|:...:|
Zfish   434 QRTEGQMGREGRRWRAGFPVSGSRLRVVTLVEHPFVFTREVDEDGNCPAGQYCLDAGTNSSETLD 498

  Fly   434 --SAIPLSGNDQF---------EGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTGEWNGMI 487
              .|....||..|         .||.:||:.::|:.:.|.:.:.:|.||.||::.  .|:|.|::
Zfish   499 HLYAERAQGNKSFLPPDYSKCCYGYCIDLLEKLSEDMNFEFDLYIVGDGKYGAVK--GGQWTGLV 561

  Fly   488 RELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYM 552
            .:||...||:|:...:|...|.:.:|||:||.:..:.||.|......| :.:|:.||...:|
Zfish   562 GDLLSGVADMAVTSFSINSARSKVIDFTSPFFSTSLGILVRSKDTAAP-IGAFMWPLHWSMW--- 622

  Fly   553 ATAYLGVSVLLFILAKF-TPYEW--PAYTDAHGE---KVESQFTLLN-CMWFAIGSLMQQGCDFL 610
                :|:.|.|.|.|.| |.|||  |.....||.   ||.|..:.|| |.....|..:...   .
Zfish   623 ----MGIFVALHITALFLTLYEWKSPFGMTPHGRNRVKVFSYSSALNLCYAILFGRTVSSK---T 680

  Fly   611 PKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAK----QTRIKYGALKGG 671
            ||..:.|.:..:|..|.|:::|||||||||.:..|:....:....| ||    ....::|.::..
Zfish   681 PKCWTGRFLMNLWAIFCLLVLSSYTANLAAVMVGEKTFEEVSGIHD-AKLHHPSQGFRFGTVRES 744

  Fly   672 STAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSY-AFLMESTSIEYVT--ER 733
            |...:.:.|....::.|..|.|...|        :||..:....... ||:|:...::|..  :.
Zfish   745 SAEDYMKKSFPEMHEYMRKFNEPTTP--------DGVATLKTDPPQLDAFIMDKALLDYEVSIDA 801

  Fly   734 NCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETS 798
            :|:|..||.....:.|||..|.|||..:.|:..:.:.:.:|.:.:|..||:|.        |...
Zfish   802 DCKLLTVGKPFAIEGYGIGLPQNSPLTSNISEFVSRYKSDGYMDMLHDKWYKV--------VPCG 858

  Fly   799 KSSSAANE---LGLANVGGVFVVLMGGM 823
            |...|..|   :|:.:..|:||:|..|:
Zfish   859 KRVFAVTETLQMGIRHFSGLFVLLCVGV 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	79/425 (19%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	111/419 (26%)
grin3bb	XP_017213803.2	Periplasmic_Binding_Protein_type1	39..427	CDD:471960	77/422 (18%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	110/416 (26%)
		Lig_chan	618..885	CDD:459656	79/293 (27%)