Protein Alignment KaiR1D and grin2db

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: XP_073782035.1
• Gene: grin2db / 100149482
• ZFINID: ZDB-GENE-100920-7
• Length: 1984
• Species: Danio rerio
• Alignment Length: 881
• Identity: 199/881 - (22%)
• Similarity: 350/881 - (39%)
• Gaps: 198/881 - (22%)

  Fly    62 PRSKLVAQIER--------ISPFDSFHAGKRVCGLLNIGVAAIFG--PQ---------SSHTASH 107
            |...||.:.||        ::|...|.:.:....::.:|..|..|  ||         ||.||..
Zfish   143 PLQGLVYEDERPLPLATGPLAPMLEFVSAQTGLPIVAVGGGAALGRVPQESGSIFLQFSSSTALQ 207

  Fly   108 VQSICDNMEIPHLENRWDYRLRRESCLVNLYPHPNTLSKAYVDIV---------RHWGWKTFTII 163
            ::.|.:.:|    |..|           ..:...:|....|.|.:         ...||:..:|:
Zfish   208 LEVIFEVLE----EYDW-----------TAFSVVSTRHHGYQDFLSVVEGLTDGSFIGWEKKSIV 257

  Fly   164 YEN---NDGIVRLQELLKAHGMTPFPITVRQLSDSGDYRPLLKQIKNSAEAHIVLDCSTERIHEV 225
            ..|   :.|.||.|.|||                           :|.|:..: |.||.|...:|
Zfish   258 MLNLTDDPGGVRTQRLLK---------------------------ENEAQVRL-LYCSQEEAEQV 294

  Fly   226 LKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLINEKIVSDVVRQWSIDE--KGL 288
            ...|...|.....|.:......|..:.|          ||   :.:::.:...:.|. ||  :.:
Zfish   295 FLAAWAAGQAGASHIWFAVGPALSELGL----------TG---LPKRLFAVRPQGWR-DEPRRRI 345

  Fly   289 LRSANLTTVRSETALMYD-----AVHLFAKALHDLDTSQQIDIHPISCDGQSTWQHGFSLINYMK 348
            .|..::.| ....||..|     ..|.......|.:.:|:|.                ..:.|..
Zfish   346 ARGVSILT-HGAVALRKDYGATGGPHFVTNCQTDGNRTQRIR----------------GRMRYFS 393

  Fly   349 IVEMKGLTNVIKFDHQGFRTDFMLDIVELTP-AGIRKIGTW-NSTL----------------PDG 395
            .:.:.|  ....|.::|:..:..||::..|| :|...:|.| |..|                ||.
Zfish   394 NITLGG--RDYSFSNEGYLANPFLDVISYTPGSGWEDVGWWENGVLRLRYPAWSRYGPFLQPPDD 456

  Fly   396 INFTRTFSQKQQEIEANLKNKTLVV---------TTILSNPYCMR-------KESAIPLSGNDQF 444
            ....|.         ..|:.:..|:         |.|..:..|.|       :|...|:  ....
Zfish   457 AQHLRV---------VTLEERPFVIVELADAASGTCIRDSVPCRRPLNASALQEGVAPV--KQCC 510

  Fly   445 EGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFERE 509
            :|:.:|::..:::.:||.|.:.||.:|.:|  .|:.|.||||:.|::.:|||:||..|||..||.
Zfish   511 KGFCIDILKRLARIVGFTYDLYLVTNGKHG--KKIDGVWNGMVGEVVYKRADMAIGSLTINEERS 573

  Fly   510 QAVDFTTPFMNLGVSILY-RKPIKQPPNLFSFLSPLSLDVWIYMATAYLG-VSVLLFILAKFTPY 572
            :.|||:.||:..|:|::. |......|:  :||.|.|..||:.|....|. |:|.:||...|:|.
Zfish   574 EVVDFSVPFVETGISVMVSRSNGTVSPS--AFLEPYSPAVWVMMFVMCLTVVAVTVFIFEFFSPV 636

  Fly   573 EWPAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGCDF-LPKALSTRMVAGIWWFFTLIMISSYTA 636
            .:.....:..:...|:||:...:|.....:....... .||..:::::..:|.||.:|.::||||
Zfish   637 GYNRSLQSGKKAGGSKFTIGKSIWLLWALVFNNSVPVENPKGTTSKIMVLVWAFFAVIFLASYTA 701

  Fly   637 NLAAFLTVERMDSPIESAEDLAKQ------TRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESA 695
            |||||:..|.....:....|...|      ..:|:|.:..|||....|.:....:|.|..:.:.
Zfish   702 NLAAFMIQEEYIDTVSGLSDKKFQHPTEQYPPLKFGTVPNGSTEKNIRSNYPDMHQYMVKYNQK- 765

  Fly   696 RPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERN--CELTQVGG--MLDTKSYGIATPPN 756
                   |..:.:..:..||.. ||:.::..:.|:..::  |::..:|.  :..|..||||...|
Zfish   766 -------SVEDAISHLKTGKLD-AFIYDAAVLNYMARKDEGCKVMTIGSGKVFATTGYGIALIKN 822

  Fly   757 SPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMG 821
            |.::..::..:|:|..:.::.:|:..|.     .|.|  ...|....:::|.:.|:.|||.:|:.
Zfish   823 SRWKRPLDLALLQLVGDDEIEMLERLWL-----SGIC--HNDKIEVMSSKLDIDNMAGVFYMLLV 880

  Fly   822 GMGVACVIAVCEFV--WKSR----KVAVEERLSAIL 851
            .||::.::...|.:  |:.|    |:....:|..:|
Zfish   881 AMGLSLLVFAWEHLVYWRLRHCMSKMGQSGKLDFLL 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	75/393 (19%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	105/398 (26%)
grin2db	XP_073782035.1	None