Protein Alignment KaiR1D and grid1

DIOPT Version :10

• Sequence 1: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_001096470.1
• Gene: grid1 / 100125089
• XenbaseID: XB-GENE-990290
• Length: 1009
• Species: Xenopus tropicalis
• Alignment Length: 931
• Identity: 266/931 - (28%)
• Similarity: 445/931 - (47%)
• Gaps: 131/931 - (14%)

  Fly     8 VLPLLLLQLILNCRKAQSLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRSKLVAQIER 72
            :|.|.|...|..|...:: ..||.||.:|.......:..|:.||..::.:..||...|:...|:.
 Frog     3 MLMLCLFPWIFQCLSVRA-DSIIHIGAIFEENAVKDDEVFQLAVSDLSLNDDILQSEKITYSIKF 66

  Fly    73 ISPFDSFHAGKRVCGLLNIGVAAIFGPQSSHTASHVQSICDNMEIPHLENRWDYRLRRES----- 132
            |...:.|.|.:..|.|:..|:.|:.......:|:.:||:.|.|.|||:      .::|.|
 Frog    67 IEANNPFQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHI------FVQRNSGGSPR 125

  Fly   133 --CLVNLYPH----------PNTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPF 185
              |..|..|.          |..|:...:.:|....|:.|.:.|:::..|..||..|........
 Frog   126 TVCQFNPSPEGEEYTLAARPPVRLNDVMLKLVTELRWQKFIVFYDSDYDIRGLQGFLDQASRLGL 190

  Fly   186 PITVRQL-----------------SDSGDYRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIG 233
            .::::::                 .:...||..|::        .:|..|.......:.:|.:..
 Frog   191 DVSLQKVDRNISRVFATLFTSMKTEELNRYRDTLRR--------AILLLSPRGAQSFISEAVETN 247

  Fly   234 MMSDYHSYLVTSLDLHTVNLDEFRYGGT-NITGFRLI-------NEKIVSDVVRQWSI---DEKG 287
            :.|....::..:.:::...:.|..:... .||..|.|       |.:.|.:..|..|:   .::|
 Frog   248 LASKDSHWVYVNEEINDAEIVELVHSALGRITVIRQIFPSLKDNNIRCVRNNHRIASLPCDPQEG 312

  Fly   288 LLRSANLTTVRSETALMYDAVHLFAKALH-DLDTSQQIDIHPISCDGQST--WQHGFSLINYMKI 349
            .|:...::.:     .:||:|.:.|.|.| .|:..:...:..::|..:||  |..|.|:::.:|.
 Frog   313 YLQMLQVSNL-----YLYDSVLMLANAFHRKLEDRKWHSMASLNCMRKSTKPWNGGRSMLDTIKK 372

  Fly   350 VEMKGLTNVIKFDHQGFRTDFMLDIV-----ELTPAGIRKIGTWNSTLPDGINFTRTFSQKQQEI 409
            ..:.|||.:::|...|.......:|:     |.....:|::.||:|.  .|.|    .|.:::.:
 Frog   373 GRITGLTGIMEFKEAGANPHVQFEILGTSYSETFGKDVRRLATWDSM--KGFN----GSLQEKPL 431

  Fly   410 EANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVPDGSYG 474
            ..:|:..||.|.|:|..|:.|..|:.  |....:::|::::::.|:|..|||.|:|...|||.||
 Frog   432 NNDLQGLTLKVVTVLEEPFVMVAENI--LGQPKRYKGFSIEILDELSNRLGFKYEIYQAPDGKYG 494

  Fly   475 SLNKLT-GEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLF 538
              ::|: |.|||||.||:.:|||:||:.:|||.|||..||||..:::..|.||.:|| ::..|:|
 Frog   495 --HQLSNGSWNGMIGELINKRADIAISAITITPERENVVDFTKRYLDYSVGILIKKP-EERINIF 556

  Fly   539 SFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVESQ---FTLLNCMWFAIG 600
            |..:|....||..:|.....|.||:|:|.:.....      |......||   .||.:.:|...|
 Frog   557 SLFAPFDFAVWACIAAVIPVVGVLIFVLNRIQAVR------AQNSSQTSQSTSSTLHSAIWIVYG 615

  Fly   601 SLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTRIKY 665
            :.:|||.:....:::.|:|.|.||.||||:.|||||||||||||.|||:||.:.:|||||..:.|
 Frog   616 AFVQQGGESAANSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLAKQVDLPY 680

  Fly   666 GALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNG---------EGVERVAKGKGSYAFL 721
            |.:|..|...:|:....:|..:..:|.|..|  ....:||         ||: |.|| :|:||||
 Frog   681 GTVKDSSVYEYFKSKGTNTLVQDRTFAELWR--TIGKNNGSDNCVSSPSEGI-RKAK-RGNYAFL 741

  Fly   722 MESTSIEY--VTERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWW 784
            .:.|.:||  :|:..|.:...|..:.:|.||||....||||...:..||:.|:.|:|.:||.|||
 Frog   742 WDVTVVEYAALTDDECSVAVTGNTISSKGYGIALQHGSPYRDIFSQRILEFQDSGRLDVLKEKWW 806

  Fly   785 KEKRGGGKCRVETSKSSSAANE---LGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKV----- 841
            ...   |:|  :.:..::|.|:   |.|.:..|||.:|..|:.:||::|..|..|.|.:.
 Frog   807 PRT---GRC--DLNSHNNAQNDGKALKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCRQDSP 866

  Fly   842 ---------AVEERLSAILNE 853
                     .|..||:::::|
 Frog   867 KEDKEVNLEQVHRRLNSLIDE 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	85/421 (20%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	150/384 (39%)
grid1	NP_001096470.1	PBP1_iGluR_delta_1	25..426	CDD:380615	85/425 (20%)
		PBP2_iGluR_delta_1	437..807	CDD:270448	150/384 (39%)