DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir93a and ATGLR1.2

DIOPT Version :9

Sequence 1:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_199651.1	Gene:	ATGLR1.2 / 834895	AraportID:	AT5G48400	Length:	867	Species:	Arabidopsis thaliana

Alignment Length:	904	Identity:	160/904 - (17%)
Similarity:	282/904 - (31%)	Gaps:	295/904 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 AITVTDCENTWNFYKNTQETSILLIAITDSDCPRLPLNRALMVPIVENGDEFPQLILDAKVQQIL 161
            ::.::|..:..|.||..     |.:.:.||                 :|:  |.|.||:.|..:
plant    61 SMALSDFYDNHNDYKTR-----LSLLVRDS-----------------HGE--PLLALDSVVDLL- 100

  Fly   162 NWKTAVVFVDQTILEENALLVKSIVHE-------SITNHITPISLILYEINDSLRGQQKRVALRQ 219
              :|..|   |.|:..|:||...::.|       .:.:..:|:||.|.:....::......:..:
plant   101 --QTEGV---QAIIGGNSLLEAKLLAELGEKARVPVISLNSPMSLSLSKYTHLIQATHNSASEVK 160

  Fly   220 ALSQF-----------APKKHEEMRQQF-LVISAFHEDIIEI----------------------- 249
            .::.|           ..:.|::.|:.. .::..|||:.:.:
plant   161 GITAFLHGFDWNSVALVLEDHDDWRESMHFMVDHFHENNVHVQSKVAFSVTSSEDSLMDRLRELK 225

  Fly   250 ----------------------AETLNMFHVGNQWMI-----------FVLDMVARDFDAGTVTI 281
                                  ||.|.|...|..|::           |:.|:.....: |.|..
plant   226 DLGTTVFVVHLSEVIATRLFPCAEKLGMMGEGFAWILTSRSMSSFHDQFIDDLTKEAME-GVVGF 289

  Fly   282 N-----LDEGANIAFALNETDP----NCQDSLNCTISEI-------SLALVNAISKITVEEESIY 330
            .     ..|..|......:|.|    ...:....:||.:       |||....::::.....::.
plant   290 KSYIPMSKELHNFTLRWRKTLPVEEVTGSEITRLSISGVWAHDVAWSLASAAEVTRMPTVTSTLL 354

  Fly   331 GEISDEEWEAIRFTKQEKQAEILEYMKEFLK------------------TNAKCSSCARWRVETA 377
            ..|.:..::.:....|....::|....|.:.                  :|.:..|.....:||.
plant   355 EAIKESRFKGLSGNFQLDDMKLLSDKFEIVNMIGSGERRVGFWNSNGSFSNRRQLSSTHDNLETI 419

  Fly   378 ITWGKSQENRKFRSTPQRDAKNRNFEFINIGYWTPVLGFVCQELAFPHIEHHFRNITMDILTVHN 442
            |..|.|.::.|.||.  |::..:....:           |.....||.:        |.:.|  :
plant   420 IWPGGSAQSPKGRSL--RESGRKKLRVL-----------VTSSNRFPRL--------MKVET--D 461

  Fly   443 PPWQILTKNSNGVIVEHKGIVMEIVK----------ELSRALNFSYYLHEASAWKEEDSLSTSAG 497
            |....:|      |||  |..:|:.:          |..|.||.:.|...|.|...:.
plant   462 PITHEIT------IVE--GFCIEVFQASIAPFNYEVEYIRWLNGTNYTKLAYALHSQK------- 511

  Fly   498 GNESDELVGSMT----------FRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPFNYTQPISVQK 552
             ::.|..||.:|          |.:||  .||..|      .|||
plant   512 -DKYDAAVGDITITSDRSMYVDFTLPY--TEMGLG------IVAA-------------------- 547

  Fly   553 YSFITRKPDEVSRIYLFTAPFTVETWFCLMGIILLTAPTLYAINRLAPLKEMRIVGLSTVKSCFW 617
                     :...:::|..|.|...|.......:||...::.|.| |..||.:......:....|
plant   548 ---------KERSMWVFFQPLTPNLWITSAAFFVLTGIIVWLIER-AENKEFQGSWPQQIGVVIW 602

  Fly   618 YIFGAL-------LQQGGMYLPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFP--KFQPGVD 673
            :.|..|       ||.        :..|.||..|...|::|||:|...|.:.:|..  :|....|
plant   603 FGFSTLVYAHREKLQH--------NLSRFVVTVWVFAVLILVTSYTATLTSMMTVQQIRFNANED 659

  Fly   674 YLNQLEDHKDIVQYGLRNGTF-FERYVQSTTREDFKHYLERAKIYGSAQEEDIEAVKRGERINID 737
            |:..|.... |....|.|.:. ..|.:...|.||:...|....:.....|.....:..||...
plant   660 YVGHLSGSL-IANAALTNSSLRAMRLLGLNTSEDYAQALMNKSVSYIVSELPYLKILLGENPG-- 721

  Fly   738 WRINLQLIVQRHFEREKECHFALGRESFVDEQIAMIVPAQSAYLHLVNRHI---KSMFRMGFIE- 798
                               ||.:.:..........:....|.....|:|.|   ::..|:..:|
plant   722 -------------------HFLMVKTQSTTNGFGFMFQKGSELAPNVSREIAKLRTSERLNEMER 767

  Fly   799 RWHQMNLPSAGKCNGKSAQRQVTNHKVNMDDMQGCFLV--LLLGFTLALLIVCGEFWYR 855
            ||....||..         ...|::.:.:...:|.|::  :...|.||:|::   .|.|
plant   768 RWFDKQLPYT---------TDDTSNPITLYRFRGLFMITGVSFAFALAVLLI---LWLR 814

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	63/297 (21%)
Ir93a	NP_650924.3	Lig_chan	576..836	CDD:306551	54/273 (20%)
ATGLR1.2	NP_199651.1	PBP1_GABAb_receptor	41..407	CDD:107361	55/376 (15%)
		ANF_receptor	55..387	CDD:279440	54/356 (15%)
		GluR_Plant	440..770	CDD:270404	83/434 (19%)
		Lig_chan	563..801	CDD:278489	54/277 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100