DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir93a and GLR2.4

DIOPT Version :9

Sequence 1:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_001328410.1	Gene:	GLR2.4 / 829299	AraportID:	AT4G31710	Length:	912	Species:	Arabidopsis thaliana

Alignment Length:	865	Identity:	154/865 - (17%)
Similarity:	280/865 - (32%)	Gaps:	264/865 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 KNTQETSILLIAITDSDCPRLPLNRALMVPIVENG----------DEFPQLILDAKVQQILNWKT 165
            :.|.:.|.::.....|..|.:..:..  .|.:::|          |:..|:...:::.::..|:.
plant   127 RTTMQASFVIEVGQKSQVPIISFSAT--SPFLDSGRSPYFFRSTYDDSSQVQAISEIIKVFGWRE 189

  Fly   166 AVVFVDQTILEENALLVKSIVHESITNHITPISLILYEINDSLRGQQKRVALRQALSQFAPKKHE 230
            .|     .:.|.||.      .|.|...:|          |:|:....|:..|..:|..|.....
plant   190 VV-----PVYENNAF------GEGIMPGLT----------DALQAINIRIPYRTVISPNATDDEI 233

  Fly   231 EM----------------RQQFLVISAFHEDIIEIAETLNMFHVGNQWMIF--VLD----MVARD 273
            .:                ..:||....|.:     |....:...|..|::.  |:|    |...|
plant   234 SVDLLKLMTKPTRVFVVHMNRFLASRVFSK-----ARETGLMKQGYAWILTNGVIDHLVLMNGTD 293

  Fly   274 FDA--GTVTINLDEGANIAFALNETDPNCQDSLNCTISEISLALVNAISKITVEEESIYGEISDE 336
            .:|  |.:      |....|.::|       .|....|.::.|       ..|.|.:|||..:.:
plant   294 IEAMQGVI------GIRTHFPISE-------ELQTFRSRLAKA-------FPVSELNIYGLRAYD 338

  Fly   337 EWEAIRFTKQEKQAEILEYMKEFLKTNAKCSSCARWRVETAITWGKSQENRK-FRSTPQRDAKNR 400
            ...|:....:|...           ||...|......:........|:...| .||..|...|..
plant   339 ATTALAMAVEEAGT-----------TNLTFSKMDGRNISDLEALSVSEYGPKLIRSLSQIQFKGL 392

  Fly   401 N--------------FEFIN--------IGYWTPVLGFVCQELA--------FPHIEHHFRNITM 435
            :              ||.:|        :|:||...|.| ::|:        |...::|...|..
plant   393 SGDYHFVDGQLHASVFEIVNVIDGGGILVGFWTQDKGLV-KDLSPSSGTTRTFSSWKNHLNPILW 456

  Fly   436 DILTVHNPP-WQILTKNSNGVIVEHKGIVMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAGGN 499
            ..:|:..|. |:|.|......|....|...:.||..:..|.     ||        ::.|....:
plant   457 PGITLTVPKGWEIPTNGKELQIGVPVGTFPQFVKVTTDPLT-----HE--------TIVTGFCID 508

  Fly   500 ESDELVGSMTFRIPYRVV----EMVQGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKP 560
            ..:.::.:|.:.:.:|.:    :..:.|...|.|..::..|       :|.|.:......:....
plant   509 FFEAVIQAMPYDVSHRFIPFGDDDGKTNDTTILANRSSYVD-------FTLPYTTSGVGMVVPLK 566

  Fly   561 DEVSRIYL-FTAPFTVETW------FCLMGIIL----------LTAPTLYAINRLAPLKEMRIVG 608
            |.|:|..| |..|.|...|      |.::|.::          .|.|..|.|:.:
plant   567 DNVARSSLIFFKPLTPGLWGMTLGSFFVVGFVVWILEHRVNSEFTGPPQYQISTM---------- 621

  Fly   609 LSTVKSCFWYIFGALLQQGGMYLP----TADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQ 669
                   ||:.|..:     ::.|    .:.:.|:||..|:.:|:||..:|..:|.:.||..:..
plant   622 -------FWFAFSIM-----VFAPRERVMSFTARVVVITWYFIVLVLTQSYTASLSSLLTTQQLN 674

  Fly   670 PGVDYLNQLEDHKDIVQYG--------------LRNGTFFE-RYVQSTTREDFKHYLERAKIYGS 719
            |....:      |:::..|              ||...|.| |.|..|:.|..:..|.:....|.
plant   675 PTETSI------KNVLAKGGPVAYQRDSFVLGKLRESGFPESRLVPFTSPEKCEELLNKGPSKGG 733

  Fly   720 AQEEDIEA----------VKRGERINIDWRINLQLIVQRHFEREKECHFALGRESFVDEQIAMIV 774
            .....:|.          .|:.:.:.:.:.::....|           |.:|.....|...|::.
plant   734 VSAAFMEVPYVRVFLGQYCKKYKMVEVPFDVDGFGFV-----------FPIGSPLVADVSRAILK 787

  Fly   775 PAQS--------AYLHLVNRHIKSMFRMGFIERWHQMNLPSAGKCNGKSAQRQVTNHKVNMDDMQ 831
            .|:|        |:...:::....           .||.|....        .|:..|:::|...
plant   788 VAESNKATQLETAWFKNIDKTCPD-----------PMNNPDPNP--------TVSFRKLSLDSFL 833

  Fly   832 GCFLVLLLGFTLALL--IVC 849
            ..|:......|||||  ::|
plant   834 LLFVAAATVCTLALLKFVIC 853

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	59/308 (19%)
Ir93a	NP_650924.3	Lig_chan	576..836	CDD:306551	52/312 (17%)
GLR2.4	NP_001328410.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100