DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir93a and Ir7d

DIOPT Version :9

Sequence 1:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_001138175.1	Gene:	Ir7d / 7354416	FlyBaseID:	FBgn0259190	Length:	594	Species:	Drosophila melanogaster

Alignment Length:	549	Identity:	95/549 - (17%)
Similarity:	177/549 - (32%)	Gaps:	170/549 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 STPQRDAKNRNFEF-------INIGYWTPVLGFV------------CQEL--------------A 422
            |.|:|....:.|.:       ||:....|.|..|            |..|              .
  Fly   135 SQPERPIMTKIFTYFMQERYNINVVILVPRLHGVQAFNVRPYTPTSCSSLEPVEIDIKDGDLWDV 199

  Fly   423 FPHIEHHFRNITMDILTVHNPPWQILTKNSNGVIVEHKGIVMEIVKELSRALNFSYYLHEASAWK 487
            ||....:.....:.::....||:..:...|:..:....|:...:::.::|.:||:..|..
  Fly   200 FPRRLKNLHGCPLSVIVWDIPPYMRINWKSSDPMDGLDGLDGLLLRIVARKMNFTLKLIP----- 259

  Fly   488 EEDSLSTSAGGNESDELVGSM-----TFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPF-NYTQ 546
                       ||.:.|:|..     ||...|:::...:.| ..|...|.|   |::..| ..|.
  Fly   260 -----------NEPNGLIGGSSFMNGTFTGAYKMLRERRAN-ITIGCAACT---PERSTFLEATS 309

  Fly   547 PISVQKYSFI--TRKPDEVSRIYLFTAPFTVETWFCLMGIILLTAPTLYAINRLAPLKEMRIVGL 609
            |.|...|..:  .|....:..:.||  ||...||..                            |
  Fly   310 PYSQMSYIIVLQARGGYSIYEVMLF--PFEKYTWLL----------------------------L 344

  Fly   610 STVKSCFWYIFGALLQQGGMY-LPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVD 673
            ||:....|.:       |..: :|:.     ::..|.:.:.|:..:|..::..|:.....:|...
  Fly   345 STILGLHWIV-------GSRWRMPSP-----ILAGWMLWIFVIRASYEASVFNFIQNSPVKPSPR 397

  Fly   674 YLNQLEDHKDIVQYGLRNGTFFERYVQSTTREDFKHYLERAKIYGSAQEEDIEAVKRGERINI-- 736
            .|:|           ..:|.|  |::  |....::..|:.....|..      .:..|:.:::
  Fly   398 TLDQ-----------ALSGGF--RFI--TDHASYRMTLKIPSFQGKT------LISAGQPVDVFD 441

  Fly   737 -----DWR---INLQLIVQRHFEREKECH---FALGRESFVDEQIAMIVPAQSAYLHLVNRHIKS 790
                 .|:   ...:..:..|..|.:: |   ..:..|..||..:.|..|..|.:...:|:.:.:
  Fly   442 ALLKAPWKTGAFTSRAFLADHLVRHRK-HRNQLVILAEKIVDNMLCMYFPHGSYFAWEINKLLFN 505

  Fly   791 MFRMGFIERWHQM----NLPSA------GKCNGKSAQRQVTNHKVNM-------DDMQGCFLVLL 838
            |...|..:...|:    |||:.      ||....|.:...|....:|       :.:.|...:.:
  Fly   506 MRSFGIFQHHSQILAWDNLPTTTDTDTPGKRIHSSTESVATGFAESMSFVVAALNCLMGALCISI 570

  Fly   839 LGFTLALLIVCGEFWYRRFRASRKRRQFT 867
            :.|.|.||              .:||.:|
  Fly   571 VVFGLELL--------------SRRRHWT 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	47/276 (17%)
Ir93a	NP_650924.3	Lig_chan	576..836	CDD:306551	45/290 (16%)
Ir7d	NP_001138175.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462912
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930