Protein Alignment Ir93a and grin2ab

DIOPT Version :9

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: XP_009304490.1
• Gene: grin2ab / 570493
• ZFINID: ZDB-GENE-070424-223
• Length: 1445
• Species: Danio rerio
• Alignment Length: 767
• Identity: 143/767 - (18%)
• Similarity: 292/767 - (38%)
• Gaps: 155/767 - (20%)

  Fly   175 LEENALLVKSIVHE------SITNHITP-----ISLILYEINDS-LRGQQKRVALRQALSQFAPK 227
            |::.|||:.:|:.|      |:.....|     |:.:...::.| :|...:.|.....:.:...:
Zfish   140 LQQEALLMLAIMEEYDWHVFSVVTTKFPGFQEFIATVRVTVDHSFVRWDLQSVVTLDGVGEPEDR 204

  Fly   228 KHEEMR--QQFLVISAFHED----IIEIAETLNMFHVGNQWMI-----FVLDMVARDFDAGTVTI 281
            .|.:::  |..:::....:|    ::|.|.:|.:...|..|::     ..|:.:...|.||.:::
Zfish   205 AHVQLKRIQSPVILLYCSKDEAALVMEEARSLGLTGAGFVWIVPSLTTGNLEHIPEAFPAGMISV 269

  Fly   282 NLDEGANIAFALNETDPNCQDSLNCTISEISLALVNAISKITVEEESIYGEISDEEW--EAIR-- 342
            ..||.   .:.|   :...||::. .||..:.|:.....:|.....|.||:....|.  .|:|
Zfish   270 TYDEW---DYPL---ETRLQDAVG-IISSAAAAMFREEGRIPDGTASCYGQSEKPEVPPSALRRY 327

  Fly   343 -----------------FTKQEKQAEILEYMKEFLKTNAKCSSCARW-----RVETAITWGKSQE 385
                             :....|...|:      |.|..:.....||     |::..: |
Zfish   328 MMGVNLGGKDHSFMDDGYQVNPKLVVIV------LNTEREWEKMGRWENHSLRLKFPV-W----- 380

  Fly   386 NRKFRSTPQRDAKNRNFEFINIGYWTPVLGFVCQELAFPHIEHHFRNITMDILT----VHNPPWQ 446
             .::.|....||...:...:.:           :|..|..::      .:||||    .::.|.:
Zfish   381 -PRYNSFGDMDADENHLSIVTL-----------EERPFVIVD------DVDILTGTCMRNSVPCR 427

  Fly   447 --ILTKNSNGVIVEH--KGIVMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAGGNESDELVGS 507
              |....:.|..|:.  ||..::|:|:::|.:.|:|.|:..:..|.         |.:.:.:...
Zfish   428 KHIKDNTTEGSYVKKCCKGFCIDILKKIARNVKFTYDLYLVTNGKH---------GKKINNVWNG 483

  Fly   508 MTFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPFNYTQP-----ISVQKYSFITRKPDEVSRIY 567
            |...:.|:...|..|        :.|:.:...:..:::.|     |||    .::|....||. .
Zfish   484 MVGEVVYKKAVMAVG--------SLTINEERSEAIDFSVPFVETGISV----MVSRSNGTVSP-S 535

  Fly   568 LFTAPFTVETWFCLMGIILL-TAPTLYAINRLAPLKEMRIVGLS--------TVKSCFWYIFGAL 623
            .|..||:...|..:..::|: ||..::....::||...|.:...        |:....|.::|.:
Zfish   536 AFLEPFSASVWVMMFVMLLIVTAIAVFLFEFISPLGFNRNLAQGKDPHGPSFTIGKAVWLLWGLV 600

  Fly   624 LQQG-GMYLPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDIVQY 687
            .... .:..|...:.:.:|..|....::.:.:|..||.||:...:|   ||.:..|.|.|....|
Zfish   601 FNNSVPVQNPRGTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEF---VDQVTGLSDRKFQSPY 662

  Fly   688 G----LRNGTFFERYVQSTTREDF---KHYLERAKIYGSAQEEDIEAVKRGERINIDWRINLQLI 745
            .    .|.||......:...|:::   ..|:  .|.:.:...:.:.::|.|:   :|..|....:
Zfish   663 SYSPPFRFGTVPNGSTERNIRKNYPAMHQYM--VKYHQTGVVDALVSLKTGK---LDAFIYDAAV 722

  Fly   746 VQRHFEREKECHFALGRESFVDEQIAMIVPAQ--SAYLHLVNRHIKSMFRMGFIERWHQMNLPSA 808
            :.....|:..|........::.......:..|  |.:..||:..|..:...|.:|......|  .
Zfish   723 LNYMAGRDDGCKLVTIGSGYIFATTGYGIAMQKGSYWKRLVDLAILGIIGDGEMEELEAQWL--T 785

  Fly   809 GKCNGKSAQRQVTNHKVNMDDMQGCFLVLLLGFTLALLIVCGE---FWYRRF 857
            |.|:.:  :.:|.:.::::|:|.|.|.:|.....|:|:....|   :|..|:
Zfish   786 GICHNE--KNEVMSSQLDVDNMAGVFYMLAAAMALSLITFVWEHLFYWRLRY 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	61/294 (21%)
		Lig_chan	576..836	CDD:306551	52/278 (19%)
grin2ab	XP_009304490.1	PBP1_iGluR_NMDA_NR2	25..382	CDD:107373	47/261 (18%)
		ANF_receptor	48..358	CDD:279440	42/230 (18%)
		PBP2_iGluR_NMDA_Nr2	393..790	CDD:270436	82/445 (18%)
		Lig_chan	544..816	CDD:278489	53/283 (19%)
		NMDAR2_C	827..1445	CDD:287527	2/9 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591354
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840