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Protein Alignment Ir93a and Gria3

DIOPT Version :9

Sequence 1:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_001268858.2	Gene:	Gria3 / 53623	MGIID:	95810	Length:	888	Species:	Mus musculus

Alignment Length:	955	Identity:	166/955 - (17%)
Similarity:	323/955 - (33%)	Gaps:	294/955 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 GGINVKYFSWNAVRLKKDFLAAITVTDCENTWNFYKNTQETSILL------------IAITDSDC 128
            ||:    |..|.|:....|..|:.:      :|..:||.|....|            .::|::.|
Mouse    31 GGL----FMRNTVQEHSAFRFAVQL------YNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFC 85

  Fly   129 PRL------------------------PLNRALMVPIVENGDEFPQLILDAKVQQIL-------- 161
            .:.                        .|:.:.:.|      .||   .||.||.::
Mouse    86 SQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTP------SFP---TDADVQFVIQMRPALKG 141

  Fly   162 ---------NWKTAVVFVDQTILEENALLVKSIVHESITNHITPISLILYEINDSLRGQQKRVAL 217
                     .|:..|...|   .|....::::|:..::.|:        :::.....|..|.:
Mouse   142 AILSLLGYYKWEKFVYLYD---TERGFSILQAIMEAAVQNN--------WQVTARSVGNIKDI-- 193

  Fly   218 RQALSQFAPKKHEEMRQQFLV------ISAFHEDIIEIAETLNMFHVGNQWMIFVLDMVARDFDA 276
             |...:...:......:::|:      |:...|.::.:.:....:|.          |:|   :.
Mouse   194 -QEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHY----------MLA---NL 244

  Fly   277 GTVTINLDE----GANI-AFAL-NETDPNCQ---------------DSLNCTISEISLALVNAIS 320
            |...|.|:.    |||| .|.: |..:|..|               ::.|..:...|....:||.
Mouse   245 GFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAIL 309

  Fly   321 KITVEEESIYGEISDEEWEAIRFTKQEKQAEILEYMKEFLKTNAKCSSCARWRVETAITWGKSQE 385
            .|.               ||.|:.::::..         :........|.   ...|:.|.:..:
Mouse   310 VIA---------------EAFRYLRRQRVD---------VSRRGSAGDCL---ANPAVPWSQGID 347

  Fly   386 NRKFRSTPQRDAKNRNFEF----------INI-----------GYWTPVLGFVCQELAFPHIEHH 429
            ..:.....|......|.:|          |::           |||.....||      |..:..
Mouse   348 IERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFV------PFSDQQ 406

  Fly   430 F-------RNITMDILTVHNPPWQILTKNSNGV--IVEHKGIVMEIVKELSRALNFSYYLH---- 481
            .       .|.|:.:.|:...|:.:..||...:  ...::|..:::..|:::.:...|.|.
Mouse   407 ISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGD 471

  Fly   482 --------EASAWKEEDSLSTSAGGNESDELVGSMTFRIPYRVVEMVQGNQFFIAAVAATVEDPD 538
                    |...|               :.:||           |:|.| :..||....|:....
Mouse   472 GKYGARDPETKIW---------------NGMVG-----------ELVYG-RADIAVAPLTITLVR 509

  Fly   539 QKPFNYTQPISVQKYSFITRKPDEVS-RIYLFTAPFTVETWFCLMGIILLTAPTLYAINRLAPLK 602
            ::..::::|......|.:.:||.:.. .::.|..|...|.|.|::...:..:..|:.::|.:|.:
Mouse   510 EEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 574

  Fly   603 ---------------------EMRIVGLSTVKSCFWYIFGALLQQGGMYLPTADSGRLVVGFWWI 646
                                 |..|.      :..|:..||.:|||....|.:.|||:|.|.||.
Mouse   575 WHLEDNNEEPRDPQSPPDPPNEFGIF------NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWF 633

  Fly   647 VVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDIVQYGLRNGTFFERYVQSTTREDFKHYL 711
            ..::::::|..||.||||..:....::....|....:|....|.:|         :|:|.|:
Mouse   634 FTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSG---------STKEFFR--- 686

  Fly   712 ERAKI--------YGSAQEEDI------EAVKRGERINIDWRINLQLIVQRHFEREKECHFALGR 762
             |:||        |..:.|..:      :.|.|..:....:...|:..:..:.|:.|.|......
Mouse   687 -RSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVG 750

  Fly   763 ESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIER-----WHQMNLPSAGKCNGKSAQRQVTN 822
            .:...:...:..|..||....||..:..:...|.:::     |:     ..|:|..|.:..:...
Mouse   751 GNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWY-----DKGECGAKDSGSKDKT 810

  Fly   823 HKVNMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFRASRKRRQFT 867
            ..:::.::.|.|.:|:.|..||:::...||.|:. ||..||.:.|
Mouse   811 SALSLSNVAGVFYILVGGLGLAMMVALIEFCYKS-RAESKRMKLT 854

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.