Protein Alignment Ir93a and Ekar

DIOPT Version :10

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 778
• Identity: 151/778 - (19%)
• Similarity: 285/778 - (36%)
• Gaps: 210/778 - (26%)

  Fly   145 GDEFPQLILDAKVQQILNWKTAVVFVDQTILEENALLVKSIVHESITNH-----ITPISLILYEI 204
            |.|...:|:|.....|                  ::|:|:|:.:.:..:     .|...|..|::
  Fly   192 GKEIHNIIIDTNSNGI------------------SILLKNILQQQMNEYKYHYLFTSFDLETYDL 238

  Fly   205 ND---------SLR-GQQKRVALRQALSQFAPKKHEEMRQQFLVISAFHEDIIEIAETLNMFHVG 259
            .|         |.| .....|.::|.|.......|...::.:|.:......|:| :|...||.
  Fly   239 EDFKYNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTILE-SEPALMFD-- 300

  Fly   260 NQWMIFVLDMVARDFDAGTVTINLDEGANIAFALNETDPNCQDSLNCTISEISLALVNAISKITV 324
               .::|       |..|..|:....                          ||.|:|    |:.
  Fly   301 ---SVYV-------FAIGLQTLEQSH--------------------------SLTLLN----ISC 325

  Fly   325 EEE-------SIYGEISDEEWEAIRFTKQEKQAEILEYMKEFLKTNAKCSSCARWRVETAITWGK 382
            |||       |:...::..||:.:....|.|..:.:::..:.:|.
  Fly   326 EEENSWDGGLSLINYLNAVEWKGLTGPIQFKDGQRVQFKLDLIKL-------------------- 370

  Fly   383 SQENRKFRSTPQRDAKNRNFEFINIGYWTP--VLGFVCQELAFPHIEHHFRNITMDILTVHNPPW 445
                             :....:.:|.|||  .|......:.|   :....|:|:.::|:...|:
  Fly   371 -----------------KQHSIVKVGEWTPHGHLNITEPSMFF---DAGSMNVTLVVITILETPY 415

  Fly   446 QILTKNSNGVIVEH-KGIVMEIVKELSRALNFSYYLH------------EASAWKEEDSLSTSAG 497
            .::....|....|. .|..::|::.:||.:.|.|.|.            |...|   :.:.....
  Fly   416 VMMHYGKNFTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEW---NGMVAQLM 477

  Fly   498 GNESDELVGSMTFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKP-D 561
            ..::|..|||||  |.|....::                      ::|:|......|.:.:.| .
  Fly   478 KYKADLAVGSMT--ITYARESVI----------------------DFTKPFMNLGISILFKVPTS 518

  Fly   562 EVSRIYLFTAPFTVETWFCLMGIILLTAPTLYAINRLAP----------LKEMRIVGLSTVKSCF 616
            |.:|::.|..|..:|.|..::....|.:..:|.:.:|:|          |:.:.|....::...|
  Fly   519 EPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSF 583

  Fly   617 WYIFGALLQQGGMYLPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDH 681
            |:..|..:||.....|.|.|.|::...|....:::|.:|..||.||||..:.      :|.:|:.
  Fly   584 WFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERM------INPIENA 642

  Fly   682 KDI-----VQYG-LRNG---TFFERYVQSTTREDFKHY-LERAKIYGSAQEEDIEAVKRGERINI 736
            :|:     :.|| |.:|   |||...|..|.::.::.. .::...:.:..|:.|:.|.:|....:
  Fly   643 EDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRVNQGNYAFL 707

  Fly   737 DWRINLQLIVQRHFEREKECHFA-LGRESFVDEQ-IAMIVPAQSAYLHLVNRHIKSMFRMGFI-- 797
            .....|..||||      :|:.. :|  ..:|.: ..:..|..|.:...::..|..:...|.|
  Fly   708 MESTMLDYIVQR------DCNLTQIG--GLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQM 764

  Fly   798 --ERWHQMNLPSAGKCNGKSAQRQVTNHKVNMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFR 858
              ::|.: |....  |..|:..:|...:.:.::.:.|.|:||:.|..:|.::...|||| .||
  Fly   765 LYDKWWK-NTDET--CTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWY-NFR 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:473866	67/300 (22%)
		Lig_chan	574..836	CDD:459656	62/287 (22%)
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	47/295 (16%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	87/409 (21%)
		Lig_chan	532..806	CDD:459656	64/290 (22%)