DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir93a and Ir85a

DIOPT Version :9

Sequence 1:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_649833.1	Gene:	Ir85a / 41052	FlyBaseID:	FBgn0037630	Length:	605	Species:	Drosophila melanogaster

Alignment Length:	808	Identity:	140/808 - (17%)
Similarity:	245/808 - (30%)	Gaps:	273/808 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 ILLIAI-------TDSDCPRLPLNRALMVPIVENGDEFPQLILDAKVQQILNWKTAVVFVDQTIL 175
            |||:||       .::..| |.|.::.:|.:     :..|::..|:::.:.     |.|.:||..
  Fly     9 ILLLAILVNLAGTRENHIP-LDLKKSSIVMV-----KMSQILCKARIKVLF-----VYFENQTSH 62

  Fly   176 EENALLVKSIVHESITNHITPISLILYEINDSLRGQQKRVALRQALSQFAPKKHEEMRQQFLVIS 240
            |....::|.:....|:|..||:..:                           |.:.:....::|:
  Fly    63 EHTGQILKEVTKCDISNQNTPLEAV---------------------------KDDGILMYMVMIT 100

  Fly   241 AFHEDIIEIAETLNMFHVGNQWMIFVLDMVARDFDAGTVTINLDEGANIAFALNETDPNCQDSLN 305
            ......:|::.........::..:|:|   .||.|
  Fly   101 TNISQPLELSLIRKKSAAKHRSHVFLL---VRDAD------------------------------ 132

  Fly   306 CTISEISLALVNAISKITVEEESIYGEISDEEWEAIRFTKQEKQAEILEYMKEFLKTNAKCSSCA 370
             |:|                          :.|....|             ::|.|.
  Fly   133 -TVS--------------------------DAWMRASF-------------RQFWKI-------- 149

  Fly   371 RWRVETAITWGKSQENRKFRSTPQRDAKNRNFEFINIGYWTPVLGFVCQELAFPHIEHHFRNITM 435
             |.:...|.:.:......:|..|..|           .|..||..   :....|.:|..|..
  Fly   150 -WLLNIVILYWRDGRLNAYRYNPFMD-----------NYLIPVDN---KPNEVPTLEQLFPK--- 196

  Fly   436 DILTVHNPPWQILTKNSNGVIVEHKGIVMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAGGNE 500
               |:.|              ::.|.:.|.|.|:..||:          .|::...|.|
  Fly   197 ---TIPN--------------MQRKPLRMCIYKDDVRAI----------FWRQGTILGT------ 228

  Fly   501 SDELVGSMTFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKPDEVSR 565
             |.|:.:.       |.|.:......            .:|.:|..........|:     ||::
  Fly   229 -DGLLAAY-------VAERLNATMMI------------TRPHSYNNHNLSSDICFL-----EVAK 268

  Fly   566 IYL-------FTAPFTVETW-----------FCLMGIILLTAPTLYAINR-LAPLKEMRIVGLST 611
            .|:       |..|.|....           .|::.....||||.:.|.| ...|....|:....
  Fly   269 EYVDVAMNIRFLVPDTFRKQAESTVSHTRDDLCVIVPKAKTAPTFWNIFRSFGSLVWALILVSVL 333

  Fly   612 VKSCFWYI------------FGALLQQGGMYLPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLT 664
            |.:.|.||            |...|......:|...|.||.:.||....:::.:.:.|||.:.:.
  Fly   334 VANVFCYILKSEVGRVPMQLFAGALTMPMTQIPPNHSIRLFLIFWLYFGLLICSAFKGNLTSMMV 398

  Fly   665 FPKFQPGVDYLNQL-EDHKDI---------VQYGLRNGTFFERYVQSTTREDFKHYLERAKIYGS 719
            |..:.|.::.|..| ..|..|         :|:.|..|...|..::....|     :...::|..
  Fly   399 FQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTLGHKHESRIREQMLE-----VSDTQMYEM 458

  Fly   720 AQEEDIEAVKRGERINIDWRINLQLIVQRHFEREKECHFALGRESF-------VDEQIAMIVPAQ 777
            .:..||..... |:.:|           ..|:.....|..|||..|       |......|||..
  Fly   459 MRNNDIRFAYL-EKYHI-----------ARFQVNSRVHMHLGRPLFHLMNSCLVPFHAVYIVPYG 511

  Fly   778 SAYLHLVNRHIKSMFRMGFIERWHQMNLPSAGKCNGKSAQRQVTNHK-----VNMDDMQGCFLVL 837
            |.||..::..|:|....||...|.::...:..|...|...|:..:..     :.:......|.:.
  Fly   512 SPYLGFLDSLIRSSHEFGFERYWDRIMNSAFIKSGVKVVNRRRGSGNDEPVVLKLQHFHAVFALW 576

  Fly   838 LLGFTLALLIVCGEFWYRRFR-ASRKRR 864
            |:|..:|.:::..|.....:. |..|||
  Fly   577 LVGIGMACIVLAWEHLTHNYNLAVTKRR 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	58/308 (19%)
Ir93a	NP_650924.3	Lig_chan	576..836	CDD:306551	62/305 (20%)
Ir85a	NP_649833.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462903
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840