DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir93a and Ir84a

DIOPT Version :9

Sequence 1:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	702	Identity:	141/702 - (20%)
Similarity:	262/702 - (37%)	Gaps:	164/702 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 EEMRQQFLVISAFHEDIIEIAETLNMFHVGNQWMIFVLDMVARDFDA-GTVTINLDEG--AN--I 289
            |.:...||.::|| ||.:. :|.|:  ||          :|.|..|| |...|...:.  ||  :
  Fly    26 ESINTNFLELAAF-EDFLR-SEHLS--HV----------LVVRGDDADGDWKIECHQKLLANYRV 76

  Fly   290 AFALNETDPNCQDSLNCTISEISLALVNAISKITVEEESIYGEISDE-------EWEAIRFTKQE 347
            .|...|...|.:|.:.......::.::|  |:..:....::|..|:.       .|..:...::.
  Fly    77 QFYRPEMSANFEDLMFYGSPRTAVLVLN--SEHVLVRRQVFGVASEAGYFNNSLAWFILGSGRES 139

  Fly   348 KQAEILEYMKEFLKTNAKCSSCARWRVETAIT---WGKSQENRKFRSTPQRDAKNRNFEFI--NI 407
            ...|  :.:.:.|       |..|..::..||   .|....:..|... .|.::..|...|  ..
  Fly   140 LPVE--QLIDQLL-------SGYRMGIDADITVALRGPDNASMLFYDV-YRISRQANTPLIIEKK 194

  Fly   408 GYWTPVLGFVCQELAFPHIEH-------HFRNITMDILTVHNPPWQILTKNSNG-----VIVEHK 460
            |.||...|:    ..|.:.::       :|.|:|:...||       ||:...|     .:.:.|
  Fly   195 GLWTHSGGY----QKFGNFKNTWVIRRRNFLNVTLIGSTV-------LTEKPPGFGDMEYLADDK 248

  Fly   461 GI---------VMEIVKELSRALNFSYYLHEASAWKE-EDSLSTSAGGNESDELVGSMTFR---- 511
            .:         ..::.:.:.|..|.|..:.....|.| .|:.|.|.       ::|.:|.|
  Fly   249 QLQQLDPMQRKTYQLFQLVERMFNLSLAISLTDKWGELLDNGSWSG-------VMGQVTSREADF 306

  Fly   512 --IPYRVVEMVQGNQFFIAAVAATVEDPDQKPF-NYTQPISVQKYSFITRKPDEVSRIYLFTAPF 573
              .|.|.|                   .|::|: .|:..:..|...|:.|.|.......:|..|.
  Fly   307 AVCPIRFV-------------------LDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNIFFEPL 352

  Fly   574 TVETWFCLMGIILLTAPTLYAINRLAPLKEMRIVGLSTVKSCFWYIFGAL----LQQGGMYLPTA 634
            :.:.|:|::.  |:|..|:..:..:. |:.|    ||.:::.|.:::..:    ||||    |..
  Fly   353 SNQVWWCVLA--LVTGSTILLLFHVR-LERM----LSNMENRFSFVWFTMLETYLQQG----PAN 406

  Fly   635 D-----SGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDIVQYGLRNGTF 694
            :     |.||::....|...:|:..|...:|..|.....:..|: |..|.|..  :..|:.|.::
  Fly   407 EIFRLFSTRLLISLSCIFSFMLMQFYGAFIVGSLLSESARSIVN-LQALYDSN--LAIGMENISY 468

  Fly   695 -FERYVQSTTREDFKHYLERAKIYGSAQEEDIEAVKRG-ERINIDWRINLQLIVQRHFEREKECH 757
             |..:..::.:.....|::  ||..|. |.:|.::::| ||| |..|......:.|.:....|
  Fly   469 NFPIFTNTSNQLVRDVYVK--KICKSG-EHNIMSLQQGAERI-IQGRFAFHTAIDRMYRLLLE-- 527

  Fly   758 FALGRESFVDEQIAM---------IVPAQSAYL-HLVNR--HIKSMFRMGFIERWHQMNLPSAGK 810
            ..:....|.|.|..|         ::|..|.:. ||.:.  |.::...:.:.::...:..|.
  Fly   528 LQMDEAEFCDLQEVMFNLPYDSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPD--- 589

  Fly   811 CN-GKSAQRQVTNHKVNMDDMQGCFLVLLLGFTLALLIVCGEF---WYRRFR 858
            |: .|::|.:     |:::........|.|....:.|:...|.   |...||
  Fly   590 CSLFKTSQAE-----VDLEHFAPALFALALAMVASALVFLLELFLHWLPDFR 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	62/299 (21%)
Ir93a	NP_650924.3	Lig_chan	576..836	CDD:306551	58/283 (20%)
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020	13/59 (22%)
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	84/413 (20%)
		Lig_chan	355..602	CDD:278489	58/274 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462890
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940