Protein Alignment Ir93a and Nmdar1

DIOPT Version :9

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 929
• Identity: 173/929 - (18%)
• Similarity: 335/929 - (36%)
• Gaps: 257/929 - (27%)

  Fly    35 LSANASLAVVVDHEY----MTVHGENILAHFEKILSDVIRENLRNGGINVKYFSWNAVRLKKDFL 95
            |..|...||||.||.    ::....:..:.|..|  .||..:.|:...:.|....:.:|....:.
  Fly    96 LIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSI--PVIGISSRDAAFSDKNIHVSFLRTVPPYY 158

  Fly    96 AAITVTDCENTW-NFYKNTQETSILLIAITDSDCPRLPLNRALMVPIVENGDE-FPQLILDAKVQ 158
            ....|      | ....:...|.:::|..:|:|      .||::......... :..:.:.|.|:
  Fly   159 HQADV------WLEMLSHFAYTKVIIIHSSDTD------GRAILGRFQTTSQTYYDDVDVRATVE 211

  Fly   159 QILNWKTAVVFVDQTILEENALLVKSIVHESITNHITPISLILYEINDSLRGQQKRVALRQALSQ 223
            .|:.::..:                    ||.|.|:.           .::..|.||.|..|.::
  Fly   212 LIVEFEPKL--------------------ESFTEHLI-----------DMKTAQSRVYLMYASTE 245

  Fly   224 FAPKKHEEMRQQFLVISAFHEDIIEIAETLNMFHVGNQWMIFVLDMVARDFDAGTVTINLDEGAN 288
            .|                  :.|...|...||...|:.|::....:.:.:...|.:.:.|:...:
  Fly   246 DA------------------QVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPDGVLGLQLEHAHS 292

  Fly   289 -----------IAFALNETDPN---------CQDS-LNCTISEISLALVNAISKITVEEESIYGE 332
                       :|.|:.|...|         |.|| :|.   |....|...:....:..|:  |:
  Fly   293 DKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNW---ESGKRLFQYLKSRNITGET--GQ 352

  Fly   333 ISDEE--------WEAIRFTKQEKQAEILEYMKEFLKTNAKCSSCARWRV-ETAITWGKSQENRK 388
            ::.::        ::.|...:|:|:..:.::..:.::..      .|.|: ::.|.|...|
  Fly   353 VAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAK------MRMRINDSEIIWPGKQ---- 407

  Fly   389 FRSTPQRDAKNRNFEFINIGYWTPVLGFVCQELAFPHIEHHFRNITMDILTVHNPPWQI------ 447
             |..|:             |...|.               |.|     :||:...|:..
  Fly   408 -RRKPE-------------GIMIPT---------------HLR-----LLTIEEKPFVYVRRMGD 438

  Fly   448 -------------LTKNSNGVIVEH--KGIVMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAG 497
                         |..||:....|.  :|..::::.|||:.:||:|            .|:.|..
  Fly   439 DEFRCEPDERPCPLFNNSDATANEFCCRGYCIDLLIELSKRINFTY------------DLALSPD 491

  Fly   498 GNESDELV----GSMTFRIPYR--VVEMVQGNQFFIAAVAATVEDPDQKPF-NYTQPISVQKYSF 555
            |.....::    |:||.|..:.  :.|:|  |:.....||....:|::..: .:::|...|..:.
  Fly   492 GQFGHYILRNNTGAMTLRKEWTGLIGELV--NERADMIVAPLTINPERAEYIEFSKPFKYQGITI 554

  Fly   556 ITRKPDEVSRIYLFTAPFTVETWFCLMGIILLTAPTLYAINRLAPL----------KEMRIVGLS 610
            :.:||...|.:..|..||:...|..:|..:.:.|..||.::|.:|.          .|.:.:.||
  Fly   555 LEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEEKALNLS 619

  Fly   611 TVKSCFWYIFGALLQQG-GMYLPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTF--PKFQPGV 672
               |..|:.:|.||..| |...|.:.|.|::...|....:::|.:|..||.|||..  ||.:
  Fly   620 ---SAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTK--- 678

  Fly   673 DYLNQLEDHKDIVQYGLRN-----------GTFFERYVQSTTREDFKHYLERAKIYGSAQ----- 721
              |:.:.|.:      |||           |:..:.|        |:..:|.:.:|.:.:
  Fly   679 --LSGINDAR------LRNTMENLTCATVKGSSVDMY--------FRRQVELSNMYRTMEANNYA 727

  Fly   722 --EEDIEAVKRGERINIDWRINLQLIVQRHFEREKECHFALGRESFVDEQIAMIVPAQSAYLHLV 784
              |:.|:.||:|:.:...|..:     :..:|..|:|......|.|......:.:...|.:...|
  Fly   728 TAEQAIQDVKKGKLMAFIWDSS-----RLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAV 787

  Fly   785 NRHIKSMFRMGFIERWHQMNLPSAGKCNGKSAQR----QVTNHKVNMDDMQGCFLVLLLGFTLAL 845
            ...|......||:|:     |......:|...|.    :.|.:.:.:.:|.|.|:::.:|....:
  Fly   788 TLAILEFHESGFMEK-----LDKQWIFHGHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGV 847

  Fly   846 LIVCGEFWYRRFRASRKRR 864
            .::..|..|::.:..:::|
  Fly   848 GLIIIEVIYKKHQVKKQKR 866

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	73/319 (23%)
		Lig_chan	576..836	CDD:306551	64/294 (22%)
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	12..405	CDD:107374	63/382 (16%)
		ANF_receptor	58..371	CDD:279440	57/342 (17%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	98/466 (21%)
		HisJ	451..>558	CDD:223904	26/120 (22%)
		Periplasmic_Binding_Protein_Type_2	<516..651	CDD:304360	34/139 (24%)
		Lig_chan	575..838	CDD:278489	64/294 (22%)
		CaM_bdg_C0	854..882	CDD:287524	2/13 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462916
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940