DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir93a and Ir68a

DIOPT Version :9

Sequence 1:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_648455.2	Gene:	Ir68a / 39269	FlyBaseID:	FBgn0036150	Length:	704	Species:	Drosophila melanogaster

Alignment Length:	620	Identity:	124/620 - (20%)
Similarity:	216/620 - (34%)	Gaps:	148/620 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   345 KQEKQAEILEYMKEFLKTNAKCSSCA--------RWRVETAITWGKSQENRKFRSTPQ----RDA 397
            :..:|.|:      |:|. .|.|.|.        .|:|:..:  |...:||......:    .|.
  Fly    94 RPSRQVEL------FVKA-IKSSDCELNVITILNGWQVQRFL--GYIYDNRSLNMQKKFVLLHDL 149

  Fly   398 KNRNFEFINIGYWTPVLG-----------FVCQELAFPHIEHHFRNITMDILTVHN-PPWQILTK 450
              |.||...|..|:..:.           :....:|||       .|...:|.:.| ..|: |.|
  Fly   150 --RLFESDMIHLWSVFIDAIFLKRQLDNKYTISTIAFP-------GILSGVLVMKNIANWE-LGK 204

  Fly   451 NSNG------------------VIVEH-------------KGIVMEIVKELSRALNFS--YY--- 479
            ..||                  .|.||             :|:.:||:..|.:||||.  ||
  Fly   205 GLNGRILFADKTSNLFGTSLPVAISEHVPMVLWANATKSFQGVEVEIMNALGKALNFKPVYYKPN 269

  Fly   480 LHEASAWKEEDSLSTSAGGNESDELVGSMTFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPFNY 544
            ..|...|.|.|..::.|.|:.:.:........|...:|:.|..:....|.....:.....|....
  Fly   270 QTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGDLHLFQVYLKLVEL 334

  Fly   545 TQPISVQKYSFITRKPDEVSRIYLFTAPFTVETWFCLMGIILLTAPTLYAI-------------- 595
            :.|.:.:..:|:|.:....:....|..||:...|..::..:.:.....|||
  Fly   335 SAPHNFECLTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSE 399

  Fly   596 -------NRLAPLKE---MRI---VGLSTVKS----------------CFWYIFGALLQQGGMYL 631
                   ||..|:..   .||   :.:|..:|                |....:..||......:
  Fly   400 FFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALPRM 464

  Fly   632 PTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQ-LEDHKDIVQYGLRNGTFF 695
            |.....|::.|::||..|:||.||..:..|.|..|..:..:|.|.. |..|.........|..||
  Fly   465 PRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLRSHIPPSTGATENRQFF 529

  Fly   696 ERYVQSTTREDFKHYLERAKIYGSAQEEDIEA-VKRGERINIDWRINLQLIVQRHFEREKECHFA 759
            ........|:    ..|:.:::|  ..:|:.: :.:|:....|....|     |:.....|...|
  Fly   530 LEANDEVARK----VGEKMEVFG--YSDDLTSRIAKGQCAYYDNEFYL-----RYLRVADESGSA 583

  Fly   760 LG--RESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIERWHQ---MNLPSAGKCNGKSAQRQ 819
            |.  :|..:...:.:.:...||....|:..|:.:...|.|.:|.:   .:||:..     .||::
  Fly   584 LHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAEGGLIAKWLKDAIEHLPAEA-----LAQQE 643

  Fly   820 VTNHKVNMDDMQGCFLVLLLGFTLALLIVCGEFWY 854
            ..   :|:......|:.||:|:.:::|.:..|.|:
  Fly   644 AL---MNIQKFWSSFVALLIGYVISMLTLLAERWH 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	72/348 (21%)
Ir93a	NP_650924.3	Lig_chan	576..836	CDD:306551	59/309 (19%)
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	51/250 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462709
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840