Protein Alignment Ir93a and GluRIA

DIOPT Version :9

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Alignment Length: 922
• Identity: 171/922 - (18%)
• Similarity: 311/922 - (33%)
• Gaps: 267/922 - (28%)

  Fly    95 LAAITVTDCENTWNFYKNTQETSILLIAITDSDCPRLPLNRALMVP-------IVENGDEFPQLI 152
            |.|:: .|..:|.:.|.||.:...:        .|..|  ..::.|       .:....::.|.|
  Fly   106 LGAVS-PDSFDTLHSYSNTFQMPFV--------TPWFP--EKVLAPSSGLLDFAISMRPDYHQAI 159

  Fly   153 LDAKVQQILNWKTAVVFVD--------QTILEE--------NALLVKSIVHESITNHITPISLIL 201
            :|  ..|...|::.:...|        |.|.:|        ...:||.|.      ::|.....|
  Fly   160 ID--TIQYYGWQSIIYLYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIA------NVTMAIEFL 216

  Fly   202 YEINDSLRGQQKRVALRQALSQFAPKKHEEMRQQFLVISAFHEDIIEIAETLNMFH-------VG 259
            :.:.|..|..:||:.|.      .|   .||.::.:|     :.:.:|......:|       :.
  Fly   217 HTLEDLGRFSKKRIVLD------CP---AEMAKEIIV-----QHVRDIKLGRRTYHYLLSGLVMD 267

  Fly   260 NQWMIFVLDMVA----------------RDFDAGTVTINLDEGANIAFALNETDPNCQDSLNCTI 308
            |.|...|::..|                |||......:   |.:..:.:.|...||...:::...
  Fly   268 NHWPSDVVEFGAINITGFRIVDSNRRAVRDFHDSRKRL---EPSGQSQSQNAGGPNSLPAISAQA 329

  Fly   309 S---EISLALVNAISKI------------------------------------------------ 322
            :   :....||.|.::|
  Fly   330 ALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRSHGGSSSSSATGTNESSALLDCNTSKGWVTPW 394

  Fly   323 -----------TVEEESIYGEIS-DEEWEAIRFTKQEKQAEILEYMKEFLKTNAKCSSCARWRVE 375
                       .||.:.:.|||. ||:...|.:|     ..::|     :..|:.....|.||.:
  Fly   395 EQGEKISRVLRKVEIDGLSGEIRFDEDGRRINYT-----LHVVE-----MSVNSTLQQVAEWRDD 449

  Fly   376 TAI------TWGKSQENRKFRSTPQRDAKNRNFEFINIGYWTPVLGFVCQELAFPHIEHHFRNIT 434
            ..:      .:..|..:.. .||...|   ||..:|           |...|..|::.  .:..|
  Fly   450 AGLLPLHSHNYASSSRSAS-ASTGDYD---RNHTYI-----------VSSLLEEPYLS--LKQYT 497

  Fly   435 MDILTVHNPPWQILTKNSNGVIVEHKGIVMEI--VKELSRALNFSYYLHEASAWKEEDSLSTSAG 497
            .....|.|..::...|:...::....||..||  |::.:......|                :.|
  Fly   498 YGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQY----------------APG 546

  Fly   498 GNESDELVGSMTFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKP-D 561
            |  .|.:||           |::: .:..||..|.|:....::..::::|......|.:.:|| .
  Fly   547 G--WDGMVG-----------ELIR-KEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVK 597

  Fly   562 EVSRIYLFTAPFTVETWFCLMGIILLTAPTLYAINRLAPLKEMRIV-------------GL---- 609
            :...::.|..|.:.|.|..::...:..:..||.:.|..|. |.|||             |:
  Fly   598 QTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPY-EWRIVRRPQADSTAQQPPGIIGGA 661

  Fly   610 ----------------STVKSCFWYIFGALLQQGGMYLPTADSGRLVVGFWWIVVIVLVTTYCGN 658
                            .|:.:.|||...|.:|||....|.:.:||:....||...|:|:::|..|
  Fly   662 TLSEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTAN 726

  Fly   659 LVAFLTFPKFQPGVDYLNQLEDHKDIVQYG--LRNGTF-FERYVQSTTREDFKHYLERAKIYGSA 720
            |.||||..:....:.....|....| |.||  |...|: |.|..|.........|: .|..:.|.
  Fly   727 LAAFLTVERMVAPIKTPEDLTMQTD-VNYGTLLYGSTWEFFRRSQIGLHNKMWEYM-NANQHHSV 789

  Fly   721 QEEDIEAVKRGERINIDWRINLQLIVQRHFEREKECH-FALGRESFVDEQ-IAMIVPAQSAYLHL 783
            ...| |.::|..:....:.:.::.....:......|. ..:||.  :|.: ..:..|..|.....
  Fly   790 HTYD-EGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRN--IDTKGFGVATPIGSPLRKR 851

  Fly   784 VNRHIKSMFRMGFIER-----WHQMNLPSAGKCNGKSAQRQVTNHKVNMDDMQGCFLVLLLGFTL 843
            :|..:.::...|.:.|     |....     :||  ..|...|.:::::.::.|.:.:|:.|..|
  Fly   852 LNEAVLTLKENGELLRIRNKWWFDKT-----ECN--LDQETSTPNELSLSNVAGIYYILIGGLLL 909

  Fly   844 ALLIVCGEFWYR 855
            |:::...||:.|
  Fly   910 AVIVAIMEFFCR 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	67/306 (22%)
		Lig_chan	576..836	CDD:306551	64/302 (21%)
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375	64/392 (16%)
		ANF_receptor	53..434	CDD:279440	60/373 (16%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	90/455 (20%)
		Lig_chan	612..907	CDD:278489	65/307 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462533
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940