Protein Alignment Ir93a and gria3b

DIOPT Version :10

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_938174.1
• Gene: gria3b / 368416
• ZFINID: ZDB-GENE-030616-53
• Length: 883
• Species: Danio rerio
• Alignment Length: 818
• Identity: 140/818 - (17%)
• Similarity: 295/818 - (36%)
• Gaps: 192/818 - (23%)

  Fly   149 PQLILDAKVQQIL-----------------NWKTAVVFVDQTILEENALLVKSIVHESITNHITP 196
            |...:|:.||.::                 .|...|...|   .:....::::|:..::.|:...
Zfish   117 PSYPIDSDVQFVIQMRPPLKGAVLSLLSHYKWDKFVYLYD---TDRGFSILQAIMEAAVANNWQV 178

  Fly   197 ISLILYEINDSLRGQQKRVALRQALSQFAPKKHEEMRQQFLV------ISAFHEDIIEIAETLNM 255
            .:..:..|.|.           |...:...:......:::|:      |:...|.::.:.:....
Zfish   179 TARSVGSITDP-----------QEFRRIIEEMDRRQEKRYLIDCEVDRINVILEQVVTLGKNSRG 232

  Fly   256 FHVGNQWMIFVLDMVARDFDAGTVTINLDE----GANIAFALNETDPNCQDSLNCTISEISLALV 316
            :|.          ::|   :.|...|:||:    ||||:                     ...::
Zfish   233 YHY----------IIA---NLGFTNISLDKVFLGGANIS---------------------GFQII 263

  Fly   317 NAISKITVEEESIYGEISDEEW-EA----IRFTKQEKQ------AEILEYMKEFLKTNAKCSSCA 370
            |..:.:..:....:..:.:.|: ||    :::|.....      ||...|::......::..|..
Zfish   264 NPENLVVQQFLQRWDRLDEREFPEAKNTPLKYTSALSYDAILVIAEAFRYLRRQRVDVSRRGSAG 328

  Fly   371 RWRVETAITWGKSQENRKFRSTPQRDAKNRNFEFIN---------------------IGYWTPVL 414
            ......|:.|.:..:..:.....|......|.:|.:                     ||||....
Zfish   329 DCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDSFGRRTNYTIDVYEMKTGGPRKIGYWNEFE 393

  Fly   415 GFV-CQELAFPHIEHHFRNITMDILTVHNPPWQILTKN-----SNGVIVEHKGIVMEIVKELSRA 473
            .|| ..:..|.:......|.|:.:.|:...|:.:..||     .|   .:::|..:::..|:::.
Zfish   394 RFVNIMDQQFTNDSSSVENRTIVVTTIMEAPYVMYKKNHMHLEGN---EKYEGYCVDLASEIAKH 455

  Fly   474 LNFSYYLH------------EASAWKEEDSLSTSAGGNESDELVGSMTFRIPYRVVEMVQGNQFF 526
            :...|.|.            |..:|               :.:||           |:|.| :..
Zfish   456 VGIKYRLSIVMDGKYGARDPETKSW---------------NGMVG-----------ELVYG-RAD 493

  Fly   527 IAAVAATVEDPDQKPFNYTQPISVQKYSFITRKPDEVS-RIYLFTAPFTVETWFCLMGIILLTAP 590
            ||....|:....::..::::|......|.:.:||.:.. .::.|..|...|.|.|::...:..:.
Zfish   494 IAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 558

  Fly   591 TLYAINRLAPLKEMRIVGLSTVK---------------SCFWYIFGALLQQGGMYLPTADSGRLV 640
            .|:.::|.:|. |.::.....||               :..|:..||.:|||....|.:.|||:|
Zfish   559 VLFLVSRFSPY-EWQLDETDEVKDPQTPPDPPNDFGIFNSLWFSLGAFMQQGCDISPRSLSGRIV 622

  Fly   641 VGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDIVQYGLRNGT---FFERYVQST 702
            .|.||...::::::|..||.||||..:....::....|....:|....|.:|:   ||.| .:..
Zfish   623 GGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRR-SKIA 686

  Fly   703 TREDFKHYLERAK--IYGSAQEEDIEAVKRGERINIDWRINLQLIVQRHFEREKECHFALGRESF 765
            ..|....|::.|:  ::.....:.:..|::.:.   .:...|:..:..:.|:.|.|.......:.
Zfish   687 VYEKMWSYMKSAEPSVFAKTTPDGVARVRKSKG---KFAFLLESTMNEYIEQRKPCDTMKVGGNL 748

  Fly   766 VDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIER-----WHQMNLPSAGKCNGKSAQRQVTNHKV 825
            ..:...:..|..||..:.||..:..:...|.:::     |:     ..|:|.......:.....:
Zfish   749 DSKGYGVATPKGSALRNAVNLAVLKLNEQGLLDKLKNKWWY-----DKGECGSGGGDSKDKTSAL 808

  Fly   826 NMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFRASRKR 863
            ::.::.|.|.:|:.|..||:::...||.|:. ||..||
Zfish   809 SLSNVAGVFYILVGGLGLAMMVALIEFCYKS-RAEAKR 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:473866	63/303 (21%)
		Lig_chan	574..836	CDD:459656	56/286 (20%)
gria3b	NP_938174.1	Periplasmic_Binding_Protein_type1	25..398	CDD:471960	45/328 (14%)
		PBP2_iGluR_AMPA	412..794	CDD:270433	80/421 (19%)