Protein Alignment Ir93a and glr-5

DIOPT Version :9

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_505244.1
• Gene: glr-5 / 179251
• WormBaseID: WBGene00001616
• Length: 932
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 115/544 - (21%)
• Similarity: 220/544 - (40%)
• Gaps: 100/544 - (18%)

  Fly   381 GKSQENRKFRSTPQRDAKNRNFEFI-------NIGYWTPVLGF-----------------VCQEL 421
            |.|.:.|:....|.:...:...:.:       :||:|.|....                 |..||
 Worm   371 GLSGDLRRLNGHPLKSNFSMRIQLLGYSGRLDDIGFWEPATNVHVNMSGDSKAQLQRNVQVSDEL 435

  Fly   422 AFPHIEHHFRNITMDILTVHNPPWQILTKNSNGVIVEHK--GIVMEIVKELSRALNFSYYLHEA- 483
                 :.|||     :.|:...|:.:|.||...:....|  |..::::.|||:.|.|:|.:|..
 Worm   436 -----KPHFR-----VTTIMERPYVMLKKNHYELDANSKFEGFCIDLLAELSKDLGFTYTIHAVK 490

  Fly   484 -----------SAWKEEDSLSTSAGGNESDELVGSMTFRIPYRVVEMVQGNQFFIA---AVAATV 534
                       .:|   |.:.......|::..|..:|  :.||..|.|...:.|::   ::...|
 Worm   491 DGKYGNDKYGNGSW---DGMMGEILRGEAEMAVAPLT--VNYRRSEAVDFTKPFLSLGISILYKV 550

  Fly   535 EDPDQKP--FNYTQPISVQKYSFITRKPDEVSRIYLFTAPFTVETWFCLMGIILLTAP---TLYA 594
            .| ||:|  |::..|:|.|.::.|......|:....|.|..|...|...........|   ..:|
 Worm   551 PD-DQQPDLFSFLNPLSWQIWTAIATSIITVTLGMYFVANVTPYEWNLNFSCCTAHEPHPAAAFA 614

  Fly   595 INRLAPLKEMRIVGL-STVKSCFWYIFGALLQQGGMYLPTADSGRLVVGFWWIVVIVLVTTYCGN 658
            .|:.||:........ :||    ||:...:|:.|..:.|.|.|.||:.|.||:..:|:::.|..|
 Worm   615 TNQEAPIVMSNNYSFWNTV----WYVLSTMLKGGCDFGPRAVSTRLLGGTWWVFYLVIISAYTAN 675

  Fly   659 LVAFLTFPKFQPGVDYLNQLED--HKDIVQYG-LRNGTFFERYVQSTTREDFKHYLERAKIYGSA 720
            |.|.||..:  |.:...| |:|  ::..:.|| :|.|:..:.:.:|       ......|::...
 Worm   676 LAAVLTVSR--PYIPIKN-LDDLANQTTISYGTIRGGSTMQFFQES-------RIAAHVKMWQYM 730

  Fly   721 QEEDIEAVKRGERINIDWRINLQLIVQR---HFEREKECHF-----ALGRESFVDEQIAMIVPAQ 777
            :::|:.....|:.:.....:|...:::.   .:|.::.|:.     .||.:.:     .:.:..:
 Worm   731 KDKDVFVTSNGKGVERALSMNYAYLMESTSLEYETQQNCNLTQIGGVLGSKGY-----GIALAKK 790

  Fly   778 SAYLHLVNRHIKSMFRMGFIE----RWHQMNLPSAGKCNGKSAQRQVTNHKVNMDDMQGCFLVLL 838
            |.:...::|.|....:.|.||    :|.:   .....|...::..:.....::|.::.|.|:.|.
 Worm   791 SEWTDRISRQILLYAKRGIIEMKKTKWWR---SKGAACASTASAVKHDRFALSMYNVAGLFITLG 852

  Fly   839 LGFTLALLIVCGEFWYRRFRASRK 862
            :|..||.::|..|..:|....::|
 Worm   853 VGIVLAAIVVIFELIHRCHHIAKK 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	76/293 (26%)
		Lig_chan	576..836	CDD:306551	55/278 (20%)
glr-5	NP_505244.1	PBP1_iGluR_delta_like	26..418	CDD:107376	8/46 (17%)
		ANF_receptor	38..377	CDD:279440	2/5 (40%)
		PBP2_iGluR_Kainate	438..819	CDD:270432	92/410 (22%)
		Lig_chan	568..855	CDD:278489	62/308 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010