Protein Alignment Ir93a and glr-2

DIOPT Version :9

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_001021114.1
• Gene: glr-2 / 175999
• WormBaseID: WBGene00001613
• Length: 977
• Species: Caenorhabditis elegans
• Alignment Length: 959
• Identity: 174/959 - (18%)
• Similarity: 336/959 - (35%)
• Gaps: 282/959 - (29%)

  Fly    85 WNAVR-----LKKDFLAAITVTDCENTWNFYKNTQETSILLIAITDSDCPRLPL----------- 133
            ||..|     :|..::..:..|:.:| :..|::.            ::..::||
 Worm    80 WNLNRIICDEMKLGYMLMLAGTNFKN-YGIYEDI------------ANHMKMPLIDWEPSKSENI 131

  Fly   134 -----NRALMVPIVENGDEFPQLILDAKVQQILNWKTAVVFVDQTILEENALLVKSIVHES---- 189
                 |..::..:..:.:   ||::|  ..|...|:..|...|....:.....:.|.:||.
 Worm   132 GKTTENNPMIFSVAPSAE---QLLID--YIQYKGWRDVVYIHDGKNADRTLRTMFSYLHEKSPKY 191

  Fly   190 ---ITNHITPISLILY-----------------EINDS---------------LRGQQKRVALRQ 219
               :.|::.|....::                 :.|||               |.|..:..|..:
 Worm   192 QLFVDNYVAPSDEEMFKEFLNEFHRRISTQHTLKSNDSSEEIDEPIPVNVIVDLEGSYRTRAFLR 256

  Fly   220 AL--SQFAPKKHEEMRQQFLV----ISAFHEDIIEI-----------------AETLNMFHVGNQ 261
            ||  |....|::..:...|.|    :|.||..:|.|                 ||..:::..|..
 Worm   257 ALEESVLVKKEYHYVFSNFDVDETDLSGFHFSLINITIFRIFDKNNKKFLKTRAEFHDVYRGGFS 321

  Fly   262 WMIFVLDMVARDFDAGTVTINLDEGANIAFALNETDPNCQDSLNCTISEISLALVNAISKITVEE 326
            ....:....|...||..|.     |..:..|:||......|.     |.:...|.|...|
 Worm   322 NTDSIPTAAAFAHDAILVA-----GKALQIAMNEHGKGIFDK-----SFVRHQLFNRGRK----- 371

  Fly   327 ESIYGEISDEEWEAIRFTKQEKQAEILEYMKEFLKTNAKCSSCARWRVETAITWGKSQENRKFRS 391
             .:|....:::.|:.:|...|...:|.|.:|:.:.|:.          :..:| |:.|.::.
 Worm   372 -GLYCRPHEDQTESRQFETFEHGKKIAEAIKKVVLTDK----------DGTLT-GRIQFDKV--- 421

  Fly   392 TPQRDAKNRNF--EFINIG-------------YWTPVLGFVCQELAFPHIEHHFRNITMD----- 436
                ..|..||  |.:.|.             .|....||:...      |.:.:....|
 Worm   422 ----TGKRTNFSAEIVEIKPGVNSLNSIWERFQWAEGEGFLLGG------ERYVQEKKKDSSQTR 476

  Fly   437 --ILTVHNPPWQ-------------ILTKNSNGVIVEHK------GIVMEIVKELSRAL-NFSY- 478
              ||.  :.|||             ::.|..|....|.|      |..::::..|::.: .|.|
 Worm   477 KGILP--SKPWQLRFNVVTVLVKPFVMLKRRNPGEPELKGNDRFEGYCIDLLNLLAKNITGFEYD 539

  Fly   479 -YLHEASAWKEEDSLSTSAGGNESDELVGSMTFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPF 542
             ::.:.:.:          |..::|   ||....|.|.:.|...     :|....|:....::..
 Worm   540 VFISDGNKY----------GSRQAD---GSWDGMIGYLLNETAD-----VAVAPLTITQERERAV 586

  Fly   543 NYTQPISVQKYSFITRKPDEVS-RIYLFTAPFTVETWFCLMGIILLTAPTLYAINRLAPLK---- 602
            ::::|......|.:.:||::.. .|:.|..|..:..|...:......:.|::.::..:|.:
 Worm   587 DFSKPFMTTGISIMIKKPEKQEFNIFSFMEPLGMTIWIFTLSSYFGVSLTIFLVSWFSPYEKRIE 651

  Fly   603 ----EMRIVGLSTVKSCFWYIFGALLQQGGMYLPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFL 663
                |..:....|:.:..|:...|.:|||...||.|.|||:....||...:::|::|..||.|||
 Worm   652 FKRGEFTVTNEFTLYNSLWFTLAAFMQQGTDILPRAVSGRIASSCWWFFTLIIVSSYTANLAAFL 716

  Fly   664 TFPKFQPGVDYLNQLEDHKDIVQYGLRNG----TFFE-----------RYVQSTTREDFKHYLER 713
            |..:..|.::.:..|.:...|: ||:..|    .|||           .::.|||::..:  ||:
 Worm   717 TLERMTPPIESVEDLANQNKIL-YGVNEGGSTAAFFEDSIVPLYKKMWNFMVSTTQKQIE--LEK 778

  Fly   714 A--------KIYGSAQEEDIEAVK--RGERINIDWRINLQLIVQRHFEREKECH----------- 757
            .        :|:.|:..:.||.|:  :|:     :...|:.....:....:.|.
 Worm   779 QSITNSTSNRIFVSSYADGIEKVRTSKGK-----YAFLLEETTNNYESGRRPCDTMKVGQNLNTL 838

  Fly   758 -----FALGRESFVDEQIAMIVPAQSAYL-HLVNRHIKSMFRMGFIERWHQMNLPSAGKCNGKSA 816
                 ..:|....|...:|::..::...| .|.|:.            |:.......|..:|.
 Worm   839 GYGIATKIGNPLRVSLNLAILYLSEKGELKKLENKW------------WYDRGQCDTGTSDGG-- 889

  Fly   817 QRQVTNHKVNMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFRASRKRRQ 865
                |:..:|:..:.|.|.:||.|..|::.....||.:|:.:.:|::.:
 Worm   890 ----TSSSLNLSKVAGIFYILLAGMVLSMCTALVEFLFRKNKENREKER 934

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	65/320 (20%)
		Lig_chan	576..836	CDD:306551	61/309 (20%)
glr-2	NP_001021114.1	Periplasmic_Binding_Protein_Type_1	7..453	CDD:299141	72/424 (17%)
		Periplasmic_Binding_Protein_Type_2	491..875	CDD:304360	78/421 (19%)
		Lig_chan	621..910	CDD:278489	63/314 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010