Protein Alignment Ir93a and Grin3b

DIOPT Version :9

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: XP_006513350.1
• Gene: Grin3b / 170483
• MGIID: 2150393
• Length: 1138
• Species: Mus musculus
• Alignment Length: 895
• Identity: 170/895 - (18%)
• Similarity: 289/895 - (32%)
• Gaps: 271/895 - (30%)

  Fly    94 FLAAITVTDCENTWNFYKNTQETSILLIAITDSDCPRLPLNRALMVPIVENGDEFP-QLILDAKV 157
            ||||.|               ||.:|.:           |.|.:..|:   |...| .|.||
Mouse   198 FLAAAT---------------ETPVLSV-----------LRREVRAPL---GAPTPFHLQLD--- 230

  Fly   158 QQILNWKTAVVFVDQTILEENALLVKSIVHESITNHITPISLILYEINDSLRGQQKRVALRQALS 222
                 |.:.:    :|||:....||::...|.       |:|:|..:.|    ....|.|..:.:
Mouse   231 -----WASPL----ETILDVLVSLVRAHAWED-------IALVLCRVRD----PSGLVTLWTSRA 275

  Fly   223 QFAPK----------KHEEMRQQFLVI-------------------SAFHEDIIEIAETLNMFHV 258
            ..|||          .::.:|....::                   :|...:::|.|..
Mouse   276 SQAPKFVLDLSQLDSGNDSLRATLALLGTLEGGGTPVSAAVLLGCSTAHAHEVLEAAPP------ 334

  Fly   259 GNQWMIFVLDMVARDFDAGT-------VTINLDEGANIAFALNETDPNCQDSLNCTISEISLALV 316
            |.||::            ||       ....|..|   ...|.||.   |.||...:.::...:.
Mouse   335 GPQWLL------------GTPLPAEALPKTGLPPG---VLVLGETG---QPSLEAAVHDMVELVA 381

  Fly   317 NAISKITV---EEESIYGEISDEEWEAIRFTKQEKQAEILEYMKEFLKTNAKCSSCARWRVETAI 378
            .|:|.:.:   |...:...::.|:   ::....|..|          :|.|:..|...::..|..
Mouse   382 RALSSMALMHPERALLPAAVNCED---LKTGGSESTA----------RTLARFLSNTSFQGRTGA 433

  Fly   379 TW--GKSQ--ENRKFRSTPQRDAKNRNFEFINIGYW-------TPVLGFVCQELAFPH------- 425
            .|  |.||  .:|.|:....|........:..:|.|       .|  |.....:..|.
Mouse   434 VWVAGSSQVHVSRHFKVWSLRRDPLGAPAWATVGSWQDGQLDFQP--GAAALRVPSPSGTQARPK 496

  Fly   426 ------IEHHFRNITMDILTVHN------PPWQ---------------ILTKNSNGVIVEH---- 459
                  :||.|      :.|..:      |..|               :.|...||.:...
Mouse   497 LRVVTLVEHPF------VFTRESDEDGQCPAGQLCLDPGTNDSARLDALFTALENGSVPRTLRRC 555

  Fly   460 -KGIVMEIVKELSRALNFSYYLHEASAWKE---EDSLSTSAGGNESDELVGSMTFRIPYRVVEMV 520
             .|..:::::.|:..|.|.:.|:.....|.   .|...|...|   |.|.|.....:
Mouse   556 CYGYCIDLLERLAEDLAFDFELYIVGDGKYGALRDGRWTGLVG---DLLAGRAHMAV-------- 609

  Fly   521 QGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKPDEVSRIYLFTAPFTVETWFCLMGII 585
              ..|.|.:..:.|.|       :|.|........:.|..|..|.|..|..|.....|..:...:
Mouse   610 --TSFSINSARSQVVD-------FTSPFFSTSLGIMVRTRDTASPIGAFMWPLHWSMWVGVFAAL 665

  Fly   586 LLTA--PTLYAINR---LAPLKEMRIVGL-----STVKSCFWYIFGALLQQGGMYLPTADSGRLV 640
            .|||  .|||....   |.|....|  |.     |.:..|:..:||..:..   ..|...:||.:
Mouse   666 HLTALFLTLYEWRSPYGLTPRGRNR--GTVFSYSSALNLCYAILFGRTVSS---KTPKCPTGRFL 725

  Fly   641 VGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHK-DIVQYGLRNGTFFERYVQSTTR 704
            :..|.|..::::::|..||.|.:...|   ..:.|:.:.|.| .....|.|.||.:|...::..:
Mouse   726 MNLWAIFCLLVLSSYTANLAAVMVGDK---TFEELSGIHDPKLHHPSQGFRFGTVWESSAEAYIK 787

  Fly   705 EDFKHYLERAKIYGSAQEEDIEAVKRG--------ERIN--------IDWRINLQLIVQRHFERE 753
            ..|      .:::...:.........|        .::|        :|:.:::          :
Mouse   788 ASF------PEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMDKSLLDYEVSI----------D 836

  Fly   754 KECHFALGRESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFI----ERWHQMNLPSAGKCNGK 814
            .:|......:.|..|...:.:|..|.....::..|......|||    ::|::| :|    | ||
Mouse   837 ADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKM-VP----C-GK 895

  Fly   815 SAQRQVTNHKVNMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFRASRKRR 864
            .........::.:..:.|.|::|.||...|||...||..:.|....|.||
Mouse   896 RVFAVTETLQMGVYHLSGLFVLLCLGLGSALLTSLGEHVFYRLVLPRIRR 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	63/307 (21%)
		Lig_chan	576..836	CDD:306551	54/290 (19%)
Grin3b	XP_006513350.1	PBP1_iGluR_NMDA_NR3	141..481	CDD:380600	70/373 (19%)
		PBP2_iGluR_NMDA_Nr3	494..888	CDD:270438	79/443 (18%)
		Lig_chan	656..922	CDD:365843	56/295 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846432
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930