Protein Alignment Ir93a and gria3a

DIOPT Version :10

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: XP_073805840.1
• Gene: gria3a / 170452
• ZFINID: ZDB-GENE-020125-5
• Length: 940
• Species: Danio rerio
• Alignment Length: 891
• Identity: 149/891 - (16%)
• Similarity: 292/891 - (32%)
• Gaps: 273/891 - (30%)

  Fly   149 PQLILDAKVQQIL-----------------NWKTAVVFVD--------QTILEENALLVKSIVHE 188
            |....|..||.:|                 .|:..|...|        |.|:|...:....:...
Zfish   120 PSFPTDTDVQFVLQMRPSLRGALLSLLAHYKWEKFVYLYDTDRGFSILQAIMESAVMNNWQVTAR 184

  Fly   189 SITNHITPISL--ILYEINDSLRGQQKRVALRQALSQFAPKKHEEMRQQFLV------ISAFHED 245
            |:.|.:.|:..  |:.|::   |.|:||                     ||:      |::..|.
Zfish   185 SVGNIVDPLEYRRIIEEMD---RRQEKR---------------------FLIDCEVERINSILEQ 225

  Fly   246 IIEIAETLNMFHVGNQWMIFVLDMVARDFDAGTVTINLDE----GANIAFALNETDPNCQDSLNC 306
            ::...:....:|       ::|      .:.|...::||:    ||||.
Zfish   226 VVIAGKNSRGYH-------YIL------ANLGFTNMSLDKVFSGGANIT---------------- 261

  Fly   307 TISEISLALVNAISKITVEEESIYGEISDEEW-----EAIRFTKQEKQ------AEILEYMKEFL 360
                 ...::|..|.|..:....:..:.:.|:     ..:::|.....      ||...|::...
Zfish   262 -----GFQIINPDSPIVQQFLQRWERLDEREFPESRSSPLKYTSALTHDAILVIAEAFRYLRRQR 321

  Fly   361 KTNAKCSSCARWRVETAITWGKSQENRKFRSTPQRDAKNRNFEFIN------------------- 406
            ...::..|........|:.|.:..:..:.....|......|.:|.:
Zfish   322 VDISRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDSFGRRSNYTVDVYEMKPGGA 386

  Fly   407 --IGYWTPVLGFV-CQELAFPHIEHHFRNITMDILTVHNPPWQILTKN-----SNGVIVEHKGIV 463
              ||||.....|| ..|....:......|.|:.:.|:...|:.:..:|     .|.   .::|..
Zfish   387 RKIGYWNEFEKFVYIVEQQVTNESSSVENRTIVVTTIMEAPYVMYKRNYMQLEGND---RYEGYC 448

  Fly   464 MEIVKELSRALNFSYYLH------------EASAWKEEDSLSTSAGGNESDELVGSMTFRIPYRV 516
            :::..|:::.:...|.|.            |...|               :.:||
Zfish   449 VDLASEIAKHVGIKYKLSIVADGKYGARDPETKTW---------------NGMVG---------- 488

  Fly   517 VEMVQGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKPDEVS-RIYLFTAPFTVETWFC 580
             |:|.| :..||....|:....::..::::|......|.:.:||.:.. .::.|..|...|.|.|
Zfish   489 -ELVYG-RADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMC 551

  Fly   581 LMGIILLTAPTLYAINRLAPLKEMRIVGLSTVK---------------SCFWYIFGALLQQGGMY 630
            ::...:..:..|:.::|.:|. |..:......|               :..|:..||.:|||...
Zfish   552 IVFAYIGVSVVLFLVSRFSPY-EWHLDDNEETKDPQTPPDPPNDFGIFNSLWFSLGAFMQQGCDI 615

  Fly   631 LPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDIVQYGLRNGTFF 695
            .|.:.|||:|.|.||...::::::|..||.||||..:....::....|....:|....|.:|
Zfish   616 SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSG--- 677

  Fly   696 ERYVQSTTREDFKHYLERAKI--------YGSAQEEDI------EAVKRGERINIDWRINLQLIV 746
                  :|:|.|:    |:||        |..:.|..:      :.|.|..:....:...|:..:
Zfish   678 ------STKEFFR----RSKIAVYEKMWSYMKSAEPSVFVKTTPDGVARVRKSKGKFAFLLESTM 732

  Fly   747 QRHFEREKECHFALGRESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIER-----W------ 800
            ..:.|:.|.|.......:...:...:..|..||....||..:..:...|.:::     |
Zfish   733 NEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRSAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 797

  Fly   801 --------HQMNLPSA-----------------------------------GKCNGKSAQRQVTN 822
                    |:...|:.                                   |:|..|.:..:...
Zfish   798 GSGGGDSKHKARCPTVSLWLTDIRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGTKDSGSKDKT 862

  Fly   823 HKVNMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFRASRKRRQFTN 868
            ..:::.::.|.|.:|:.|..||:.:...||.|:..:.:::.:...|
Zfish   863 SALSLSNVAGVFYILVGGLGLAMTVALVEFCYKSHQETKRLKLAKN 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:473866	59/300 (20%)
		Lig_chan	574..836	CDD:459656	61/344 (18%)
gria3a	XP_073805840.1	None