Protein Alignment Ir93a and grin2b

DIOPT Version :9

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: XP_017948700.2
• Gene: grin2b / 100490580
• XenbaseID: XB-GENE-949327
• Length: 1449
• Species: Xenopus tropicalis
• Alignment Length: 906
• Identity: 169/906 - (18%)
• Similarity: 329/906 - (36%)
• Gaps: 256/906 - (28%)

  Fly   115 ETSILLIAITD----------SDCPRLPLN-RALMVPIVENGDE-----FPQLILDAKVQQILNW 163
            :.:::|:..||          .|...||:. |..:|.:.|:..:     ...|:.|.|||
 Frog    31 DIAVILVGTTDEVAIKDVHEKDDFHHLPVTPRVALVTMNESDPKSIITRICDLMSDKKVQ----- 90

  Fly   164 KTAVVFVDQTILEENALLVKSIVHESITNHITPI-------SLILYEINDSLRGQQKRVALRQAL 221
              .|||.|.|..|..|.::..|..::    :|||       |:|:.:..::           ...
 Frog    91 --GVVFGDDTDQEAIAQILDFISVQT----LTPILGIHGGSSMIMADKEEA-----------SMF 138

  Fly   222 SQFAPKKHEEMRQQFLVISAFHEDIIEIAETLNMFHVGNQWMIFVL------------DMVARDF 274
            .||.|    .:.||..|:....|:.              .|.||.:            :.|....
 Frog   139 FQFGP----SIEQQASVMLNIMEEY--------------DWYIFSIVTTYFPGYQDFENKVRSTI 185

  Fly   275 DAGTVTINLDEGANIAFALNETDPNCQDSLN----------CTISEI--------SLALVN---- 317
            :...|...|:|..::..:|::.|...|:.|.          ||..|.        |:.|..
 Frog   186 ENSFVGWELEEVIHLDMSLDDNDSKIQNQLKKLQSPVILLYCTKEEATYIFEVAHSVGLTGYGYT 250

  Fly   318 --AISKITVEEESIYGE-------ISDEEWE-----------AIRFTKQEKQAEILEYMKEFLKT 362
              ..|.:..:.:::..|       :|.:||:           ||..|   ..:.:|.......::
 Frog   251 WIVPSLVAGDTDTVPAEFPTGLISVSYDEWDYDLPARVRDGIAIITT---AASTMLSEHNSIPQS 312

  Fly   363 NAKCSSCARWRVETAITWGKSQENRKFRSTPQRDAKNRNFEFINIGY----------------WT 411
            .:.|.:....||..|....:...|..|        :.||..|...||                |.
 Frog   313 KSSCYNIQESRVYEAHMLKRYLINVTF--------EGRNLSFSEDGYQMHPKLVIILLNQQRKWE 369

  Fly   412 PVLGFVCQEL-----------AFPHIEHHFRNITMDILTVHNPPW-------------------- 445
            .|..:..:.|           .:|:.|.| ::..:.|:|:...|:
 Frog   370 RVGKYKDRSLKMKYYVWPVFELYPNSEEH-KDEHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPC 433

  Fly   446 --QILTKN---SNGVIVEH--KGIVMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAGGNESDE 503
              ||.|:|   ..|..::.  ||..::|:|::::.:.|:|.|:..:..|....::.:..|
 Frog   434 RKQIRTENRTEEGGNYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKINGTWNG----- 493

  Fly   504 LVGSMTFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPFNYTQP-----ISVQKYSFITRKPDEV 563
            ::|.:..:..|            :|..:.|:.:...:..:::.|     |||    .::|....|
 Frog   494 MIGEVVTKRAY------------MAVGSLTINEERSEVVDFSVPFIETGISV----MVSRSNGTV 542

  Fly   564 SRIYLFTAPFTVETWFCLMGIILL-TAPTLYAINRLAPLKEMRIV-------GLS-TVKSCFWYI 619
            |. ..|..||:.:.|..:..::|: :|..::.....:|:...|.:       |.| |:....|.:
 Frog   543 SP-SAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIWLL 606

  Fly   620 FGALLQQG-GMYLPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHK- 682
            :|.:.... .:..|...:.:::|..|....::.:.:|..||.||:...::   ||.::.|.|.|
 Frog   607 WGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEY---VDQVSGLSDKKF 668

  Fly   683 -------DIVQYG-LRNGTFFERYVQSTTREDFKHYLE----RAKIYGSAQEEDIEAVKRGERIN 735
                   ...::| :.||        ||.|....:|||    ..|....:.::.:.::|.|:
 Frog   669 QRPNDFSPAFRFGTVPNG--------STERNIRNNYLEMHSYMVKFNQRSVQDALLSLKTGK--- 722

  Fly   736 IDWRINLQLIVQRHFEREKECHF-ALGR-ESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIE 798
            :|..|....::.....|::.|.. .:|. :.|......:.:...|.:...|:..|..:|..|.:|
 Frog   723 LDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEME 787

  Fly   799 RWHQMNLPSAGKCNGKSAQRQVTNHKVNMDDMQGCFLVLLLGFTLALLIVCGE---FWYRR 856
            ....:.|  .|.|:.:  :.:|.:.::::|:|.|.|.:|.....|:|:....|   ||..|
 Frog   788 ELEALWL--TGICHNE--KNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFFWQLR 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	58/318 (18%)
		Lig_chan	576..836	CDD:306551	55/284 (19%)
grin2b	XP_017948700.2	PBP1_iGluR_NMDA_NR2	28..383	CDD:380601	73/402 (18%)
		PBP2_iGluR_NMDA_Nr2	400..800	CDD:270436	81/437 (19%)
		NMDAR2_C	837..1449	CDD:402274	3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910