Protein Alignment Ir93a and gria4

DIOPT Version :10

• Sequence 1: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: XP_031751480.1
• Gene: gria4 / 100125052
• XenbaseID: XB-GENE-5838893
• Length: 902
• Species: Xenopus tropicalis
• Alignment Length: 781
• Identity: 151/781 - (19%)
• Similarity: 290/781 - (37%)
• Gaps: 157/781 - (20%)

  Fly   163 WKTAVVFVDQTILEENALLVKSIVHESITNHITPISLILYEIND-SLRGQQKRVALRQALSQFAP 226
            |...|...|   .:....::::|:.::..|.....::.:...|| |.|...:.:..||. ::|..
 Frog   151 WNHYVFLYD---TDRGYSILQAIMEKAGQNGWQVSAICVENFNDASYRRLLEDLDRRQE-NKFVI 211

  Fly   227 KKHEEMRQQFLVISAFHEDIIEIAETLNMFHVGNQWMIFVLDMVARDFDAGTVTINLDE----GA 287
            ....|..|..|      |.|:.:.:.:..:|.          ::|   :.|...|:||.    ||
 Frog   212 DCEVERLQNIL------EQIVSVGKHVKGYHY----------IIA---NLGFKDISLDRFMHGGA 257

  Fly   288 NIAFALNETDPNCQDSLNCTISEISLALVNAISK--ITVEEESIYGEISDEEW-EAIRFTKQEKQ 349
            |:.              ...:.:.:..:|..:.:  .|:::....|..|..:: .|:.:......
 Frog   258 NVT--------------GFQLVDFNTPIVTELMQRWKTLDQREYPGSESPPKYTSALTYDGVLVM 308

  Fly   350 AE---ILEYMKEFLKTNAKCSSCARWRVETAITWGKSQENRKFRSTPQRDAKNRNFEF------I 405
            ||   ||...|..|........|.   ...|..||:..:..:.....:......|.:|      :
 Frog   309 AEAFRILRRQKIDLSRRGNAGDCL---ANPAAPWGQGIDMERTLKQVRIQGLTGNIQFDHYGRRV 370

  Fly   406 N---------------IGYWTPV--LGFVCQELAFPHIEHHFRNITMDILTVHNPPWQILTKNSN 453
            |               ||||..:  |..:..|.||.:......|.|:.:.|:...|:.:..||..
 Frog   371 NYTMDVLELKSNGLRKIGYWNDMDKLVLLQHEPAFKNDSSGIENRTVIVTTILEAPYVMYKKNHE 435

  Fly   454 GVIVE----HKGIVMEIVKELSRALNFSYYLHEASAWKEEDSLSTSAGGNESD-ELVGSMTFRIP 513
              ::|    .:|..:::..|:::.:...|.:......|        .|..:|: ::...|...:.
 Frog   436 --LLEGNDKFEGYCVDLAYEIAKHIGIKYKIAIVPDGK--------YGARDSETKIWNGMVGELV 490

  Fly   514 YRVVEMVQGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKPDEVS-RIYLFTAPFTVET 577
            |...|        ||....|:....::..::::|......|.:.:||.:.. .::.|..|...|.
 Frog   491 YGKAE--------IAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEI 547

  Fly   578 WFCLMGIILLTAPTLYAINRLAPL----------KEMRIVGLST-------VKSCFWYIFGALLQ 625
            |.|::...:..:..|:.::|.:|.          ||    |.|.       :.:..|:..||.:|
 Frog   548 WMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKE----GPSDQPPNEFGIFNSLWFSLGAFMQ 608

  Fly   626 QGGMYLPTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDIVQYGLR 690
            ||....|.:.|||:|.|.||...::::::|..||.||||..:....::....|....:|. ||..
 Frog   609 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA-YGTL 672

  Fly   691 NGTFFERYVQSTTREDFKHYLERAKI--------YGSAQEEDI------EAVKRGERINIDWRIN 741
            :.        .:|:|.||    |:||        |..:.|..:      |.|.|..:....:...
 Frog   673 DA--------GSTKEFFK----RSKIAVYEKMWTYMKSAEPSVFTKTTAEGVARVRKSKGKFAFL 725

  Fly   742 LQLIVQRHFEREKECHFALGRESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIER-----WH 801
            |:..:..:.|:.|.|.......:...:...:..|..|...:.||..:..:...|.:::     |:
 Frog   726 LESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKHSQLRNAVNLAVLKLNEQGLLDKLKNKWWY 790

  Fly   802 QMNLPSAGKCNGKSAQRQVTNHKVNMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFRASRKRRQF 866
                 ..|:|.......:.....:::.::.|.|.:|:.|..||:|:...||.|:. ||..||.:.
 Frog   791 -----DKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS-RAEAKRMKL 849

  Fly   867 T 867
            |
 Frog   850 T 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:473866	60/290 (21%)
		Lig_chan	574..836	CDD:459656	61/297 (21%)
gria4	XP_031751480.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611	49/288 (17%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	83/420 (20%)