| Sequence 1: | NP_650921.1 | Gene: | CG15696 / 42469 | FlyBaseID: | FBgn0038833 | Length: | 179 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_079141.2 | Gene: | NANOG / 79923 | HGNCID: | 20857 | Length: | 305 | Species: | Homo sapiens |
| Alignment Length: | 171 | Identity: | 43/171 - (25%) |
|---|---|---|---|
| Similarity: | 69/171 - (40%) | Gaps: | 37/171 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 35 PFHPYAHPASYVS--KESGGSPPASAAEAQIPVYDWLQYTRYHPP------KLPRA---LRQNAP 88
Fly 89 AKRT--PGRLP------------RIP---------FTPQQLQALENAYKESNYLSAEDANKLADS 130
Fly 131 LELTNTRVKIWFQNRRARERREKREKDESCDSTFSSNASSP 171 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG15696 | NP_650921.1 | Homeodomain | 95..144 | CDD:459649 | 16/69 (23%) |
| NANOG | NP_079141.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..96 | 22/93 (24%) | |
| COG5576 | 74..191 | CDD:227863 | 24/99 (24%) | ||
| Homeodomain | 97..152 | CDD:459649 | 17/54 (31%) | ||
| Required for DNA-binding. /evidence=ECO:0000269|PubMed:25825768 | 122..151 | 10/28 (36%) | |||
| 8 X repeats starting with a Trp in each unit | 196..240 | ||||
| Sufficient for transactivation activity. /evidence=ECO:0000250 | 196..240 | ||||
| Sufficient for strong transactivation activity. /evidence=ECO:0000250 | 241..305 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||