| Sequence 1: | NP_650921.1 | Gene: | CG15696 / 42469 | FlyBaseID: | FBgn0038833 | Length: | 179 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_082292.1 | Gene: | Nanog / 71950 | MGIID: | 1919200 | Length: | 305 | Species: | Mus musculus |
| Alignment Length: | 180 | Identity: | 34/180 - (18%) |
|---|---|---|---|
| Similarity: | 64/180 - (35%) | Gaps: | 60/180 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 38 PYAHPASYVSKESGGSPPASAAEAQIPVYDWLQYTRYHPPKL-----------------PRALRQ 85
Fly 86 NAPAKRTPG-----------------------------RLPRIPFTPQQLQALENAYKESNYLSA 121
Fly 122 EDANKLADSLELTNTRVKIWFQNRRARERREKREKDESCDSTFSSNASSP 171 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG15696 | NP_650921.1 | Homeodomain | 95..144 | CDD:459649 | 16/48 (33%) |
| Nanog | NP_082292.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..30 | 6/35 (17%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 46..95 | 4/48 (8%) | |||
| Sufficient for interaction with SALL4. /evidence=ECO:0000269|PubMed:16840789 | 96..155 | 20/58 (34%) | |||
| Homeodomain | 98..153 | CDD:459649 | 19/54 (35%) | ||
| Required for DNA-binding. /evidence=ECO:0000250|UniProtKB:Q9H9S0 | 123..152 | 10/28 (36%) | |||
| PTZ00395 | <190..>250 | CDD:185594 | |||
| 10 X repeats starting with a Trp in each unit | 198..247 | ||||
| Sufficient for transactivation activity | 198..247 | ||||
| Sufficient for strong transactivation activity | 248..305 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||