Protein Alignment CG15696 and MSX2

DIOPT Version :10

• Sequence 1: NP_650921.1
• Gene: CG15696 / 42469
• FlyBaseID: FBgn0038833
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 193
• Identity: 59/193 - (30%)
• Similarity: 83/193 - (43%)
• Gaps: 37/193 - (19%)

  Fly     4 FSIEYILN-----RAGDRYVGTNASLGVLQR--------LRASLPFHPYAHPASYVSKESGGSPP 55
            ||:|.:::     :........:||.|...|        .|.:....|...|....|.:|..|..
Human    47 FSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSED 111

  Fly    56 ASAAEAQIPVYDWLQYT-RYHPPKLPRALRQNAPA-----KRTPGRLPRIPFTPQQLQALENAYK 114
            .:|         |:|.. ||.||  ||.:   :|.     |....|.||.|||..||.|||..::
Human   112 GAA---------WMQEPGRYSPP--PRHM---SPTTCTLRKHKTNRKPRTPFTTSQLLALERKFR 162

  Fly   115 ESNYLSAEDANKLADSLELTNTRVKIWFQNRRARERR----EKREKDESCDSTFSSNASSPEP 173
            :..|||..:..:.:.||.||.|:||||||||||:.:|    |..:...:......|:.|.|.|
Human   163 QKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFP 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15696	NP_650921.1	Homeodomain	95..144	CDD:459649	24/48 (50%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		3/23 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		11/35 (31%)
		Homeodomain	143..199	CDD:459649	29/55 (53%)