Protein Alignment CG15696 and HOXA1

DIOPT Version :10

• Sequence 1: NP_650921.1
• Gene: CG15696 / 42469
• FlyBaseID: FBgn0038833
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_005513.2
• Gene: HOXA1 / 3198
• HGNCID: 5099
• Length: 335
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 50/190 - (26%)
• Similarity: 80/190 - (42%)
• Gaps: 50/190 - (26%)

  Fly     5 SIEYILNRAGDRYVGTNASLGVLQRLRASLPFHPYAHPASYVSKESGGSPPASAAEAQIPVYDWL 69
            |.:||.:..|..:    .||.:.....:..|.|        .|.:.....|||...:....:||:
Human   156 SPQYIHHSYGQEH----QSLALATYNNSLSPLH--------ASHQEACRSPASETSSPAQTFDWM 208

  Fly    70 QYTRYHPPKL-----------PRALRQNAPAKRTPGRLPRIPFTPQQLQALENAYKESNYLSAED 123
            :..| :|||.           |.|:|.|              ||.:||..||..:..:.||:...
Human   209 KVKR-NPPKTGKVGEYGYLGQPNAVRTN--------------FTTKQLTELEKEFHFNKYLTRAR 258

  Fly   124 ANKLADSLELTNTRVKIWFQNRRARERREKRE------------KDESCDSTFSSNASSP 171
            ..::|.||:|..|:|||||||||.::::.::|            .||..:.:...::|||
Human   259 RVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAEESSEKSSSSP 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15696	NP_650921.1	Homeodomain	95..144	CDD:459649	18/48 (38%)
HOXA1	NP_005513.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..80
		Interaction with OGT. /evidence=ECO:0000250|UniProtKB:P09022	75..203		12/58 (21%)
		COG5576	176..>286	CDD:227863	38/132 (29%)
		Antp-type hexapeptide	204..209		2/4 (50%)
		Homeodomain	233..286	CDD:459649	24/66 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..335		7/38 (18%)