Protein Alignment CG15696 and TLX3

DIOPT Version :10

• Sequence 1: NP_650921.1
• Gene: CG15696 / 42469
• FlyBaseID: FBgn0038833
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_066305.2
• Gene: TLX3 / 30012
• HGNCID: 13532
• Length: 291
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 56/215 - (26%)
• Similarity: 75/215 - (34%)
• Gaps: 78/215 - (36%)

  Fly    23 SLGVLQRLRA----SLPFHPYAHPASYVSKESGGSP-------PASAAEAQIPVYDWLQYT---- 72
            |.|:.|.|.:    |.|.......|||:....||.|       |||.|....|..|...|:
Human    17 SFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLS 81

  Fly    73 ---------RYH-------PPKLPRAL-----------------------------RQNAPAKRT 92
                     ..|       ||.||.||                             |..|.|..|
Human    82 LAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALT 146

  Fly    93 P------------------GRLPRIPFTPQQLQALENAYKESNYLSAEDANKLADSLELTNTRVK 139
            |                  .:.||..|:..|:..||..:....||::.:...||.||::|:.:||
Human   147 PFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVK 211

  Fly   140 IWFQNRRARERREKREKDES 159
            .||||||.:.||:..|:.|:
Human   212 TWFQNRRTKWRRQTAEEREA 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15696	NP_650921.1	Homeodomain	95..144	CDD:459649	17/48 (35%)
TLX3	NP_066305.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		12/38 (32%)
		Homeodomain	167..223	CDD:459649	21/55 (38%)