Protein Alignment CG15696 and Tlx2

DIOPT Version :10

• Sequence 1: NP_650921.1
• Gene: CG15696 / 42469
• FlyBaseID: FBgn0038833
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_033418.1
• Gene: Tlx2 / 21909
• MGIID: 1350935
• Length: 284
• Species: Mus musculus
• Alignment Length: 216
• Identity: 52/216 - (24%)
• Similarity: 80/216 - (37%)
• Gaps: 72/216 - (33%)

  Fly     4 FSIEYILN------------RAGDRYVGTNASLGVLQRLRASLPFH---PYAHPASYVSKESGGS 53
            |.|:.||:            ::|..: |.:|:.        |..||   .||...|..|...|..
Mouse    19 FGIDQILSGPEPPGGGLGPGQSGQSH-GESAAF--------SSGFHGASGYAPAGSLASLPRGSG 74

  Fly    54 -----------------PPASAAEAQIP--------------VYDWLQY-TRYHPPKLPRAL--- 83
                             ||.|.|...:|              .:.|:.. .|:...:|..||
Mouse    75 VGPGGVIRVPAHRPLPVPPPSGAAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPF 139

  Fly    84 ----------RQNAPAKRTPGRLPRIPFTPQQLQALENAYKESNYLSAEDANKLADSLELTNTRV 138
                      :...|.||   :.||..|:..|:..||..:....||::.:...||.:|.:|:.:|
Mouse   140 SGTRRIGHPYQNRTPPKR---KKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQV 201

  Fly   139 KIWFQNRRARERREKREKDES 159
            |.||||||.:.||:..|:.|:
Mouse   202 KTWFQNRRTKWRRQTAEEREA 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15696	NP_650921.1	Homeodomain	95..144	CDD:459649	16/48 (33%)
Tlx2	NP_033418.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..52		6/40 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..104		5/25 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..166		6/28 (21%)
		Homeodomain	158..214	CDD:459649	20/55 (36%)